Abstract
Published prevalence data on restrictive lung function (rLF) in the general population vary widely from 5-20% and are obtained by spirometry only. Therefore, the aim of our study was to determine the prevalence and severity of rLF in a general population according to both spirometric and bodyplethsymographic excepted equations.
Data was obtained from the Austrian LEAD Study, a longitudinal, observational, population-based cohort study. In total 9998 participants (46.6% male) were included in this analysis. rLF was defined spirometrically by FEV1/FVC>LLN and FVC<LLN and bodyplethysmographically by TLC<LLN. Severity of rLF was defined as mild (>60%pred), moderate (40-60%pred) and severe (<40%pred).
Overall, the prevalence of rLF by spirometric criteria is 3.4% (N=337) and by bodyplethysmographic criteria 0.9% (N=85; p<0.001). rLF is more prevalent in male vs. female (1.6 vs 0.2; p<0.001; Table1) and independent of age, although no rLF was found in age <18years. Nearly all rLF were mild, independently from the parameter used (FVC% or TLC%), which both are highly correlated (R=0.6, p<0.001).
The prevalence of rLF in our general population is significantly less than previously reported; especially when bodyplethysmographic criteria are applied. Therefore, existing prevalence data on rLF may be interpreted with caution and should be validated by bodyplethysmography in the future.
Footnotes
Cite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA358.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2019
