Abstract
Among 30-70% of surgically treated lung cancer (LC) will have a recurrence in the first 5 years after treatment. It has also been documented that as time passes, the relapse rates decrease, but the probability of second tumors increase. The aim was to characterise LC recurrence and second tumors after being surgically treated.
Cross-sectional retrospective study from patients who have undergone surgical treatment for primary LC from 2009 to 2016. We analysed characteristics of recurrences and second tumors and their association with the 7th edition TNM, histopathologic type, and mortality.
208 patients were included with surgically treated LC. The most frequent TNM stage was IB (32%) and the most frequent histologic type was adenocarcinoma (AC) (57%) followed by squamous cell LC (SCC) (27%). Mortality rate was 36%.
75 patients had LC recurrences (36%). IB stage was the most common (37%), as was AC type (60%). Recurrences were 13% local, 31% regional, and 56% distant. Mortality rate in these patients was 68%. Within the non-recurrence group the most common stage was IA (38%) and histologic type was AC (55%). Mortality was 21%.
Moreover, second tumors were seen in 12 patients (6%). The most frequent histologic type was AC (50%) and stages IA and IB were more commonly seen. All second tumors were pulmonary and mortality was 42%. We observed that AC recurrences were more often than SCC, however the later were more commonly seen as second tumors.
From the data obtained of surgically treated LC, the most commonly seen recurrence was AC type and there was an increased mortality in the recurrence group. The other variables pertaining the different groups studied did not differ from one another.
Footnotes
Cite this article as: European Respiratory Journal 2019; 54: Suppl. 63, PA3035.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2019