Extract
Cadmium is a metal that is widely spread in the environment and human populations are exposed to it through food, mainly grains and vegetables. The tobacco plants accumulate cadmium, and tobacco smokers accumulate the cadmium in tobacco smoke, which is absorbed in the lungs [1]. Occupational exposure to cadmium has been linked to the development of emphysema and impaired lung function [2, 3]. Increased levels of blood cadmium (B-Cd) or urinary cadmium are associated with lower lung function, and it has been suggested that cadmium, in the low-dose interval, is a risk factor for impaired lung function [1, 4].
Abstract
In this general population sample with detailed control for smoking habits there is an association between blood cadmium and emphysema based on lung computed tomography http://bit.ly/2K9S39J
Footnotes
The study is based on random population sample, which needs a Swedish ethical application to be analysed. The lead author (K. Torén) affirms that the manuscript is an honest, accurate, and transparent account of the study being reported; that no important aspects of the study have been omitted; and that any discrepancies from the study as planned have been explained.
Conflict of interest: K. Torén has nothing to disclose.
Conflict of interest: A-C. Olin has nothing to disclose.
Conflict of interest: Å. Johnsson has nothing to disclose.
Conflict of interest: J. Vikgren reports reports personal fees from Boehringer Ingelheim outside the submitted work.
Conflict of interest: N. Forsgard has nothing to disclose.
Conflict of interest: G. Bergström has nothing to disclose.
Conflict of interest: G. Sallsten has nothing to disclose.
Conflict of interest: L. Barregård has nothing to disclose.
Support statement: The main funding body of the Swedish Cardiopulmonary Bioimage Study (SCAPIS) was the Swedish Heart and Lung Foundation. The study was also funded by the Knut and Alice Wallenberg Foundation, the Swedish Research Council (VR), VINNOVA and the Swedish Council for Working Life, Health, and Welfare (FORTE). In addition, there was support from the Sahlgrenska University Hospital, strategic grants from ALF/LUA in Western Sweden and from the Sahlgrenska Academy at University of Gothenburg. Funding information for this article has been deposited with the Crossref Funder Registry.
- Received April 18, 2019.
- Accepted July 27, 2019.
- Copyright ©ERS 2019
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