Extract
We thank B. Hartley and co-workers for their correspondence on our analysis of the IMPACT triple therapy trial [1]. We welcome this opportunity to correct some misunderstanding of the computation of monthly rates of exacerbation, when converted from the cumulative incidence curve, as applied to the IMPACT trial.
Abstract
The IMPACT trial of triple therapy in COPD confirms that benefit on exacerbations is only in first month with no benefit in following 11 months, likely due to inclusion of asthma-like patients, suggesting a precision medicine opportunity in COPD treatment http://bit.ly/2YxQpH0
Footnotes
Conflict of interest: S. Suissa reports personal fees for board membership from Novartis and Boehringer Ingelheim, grants from Boehringer Ingelheim/Pfizer, personal fees for lectures from AstraZeneca, outside the submitted work.
Conflict of interest: A. Ariel reports personal fees from AstraZeneca and Teva, personal fees and non-financial support from Boehringer Ingelheim, outside the submitted work.
- Received June 26, 2019.
- Accepted June 27, 2019.
- Copyright ©ERS 2019
INDIVIDUALS
Log in using your username and password
LIBRARY USERS
Log in through your institution
Purchase access
CONTACT US
If you have any questions about the ERS publications website, please contact journals@ersnet.org
