European Respiratory Journal: 53 (6)

01 June 2019; volume 53, issue 6

Editorials

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A guide for respiratory physiotherapy postgraduate education: presentation of the harmonised curriculum
Thierry Troosters, Daniel Langer, Chris Burtin, Michelle Chatwin, Enrico M. Clini, Margareta Emtner, Rik Gosselink, Kathleen Grant, Deniz Inal-Ince, Agnieszka Lewko, Eleanor Main, Beatrice Oberwaldner, Nathalie Tabin, Fabio Pitta

European Respiratory Journal 53 (6) 1900320; DOI: 10.1183/13993003.00320-2019 Published 5 June 2019
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GINA 2019: a fundamental change in asthma management
Helen K. Reddel, J. Mark FitzGerald, Eric D. Bateman, Leonard B. Bacharier, Allan Becker, Guy Brusselle, Roland Buhl, Alvaro A. Cruz, Louise Fleming, Hiromasa Inoue, Fanny Wai-san Ko, Jerry A. Krishnan, Mark L. Levy, Jiangtao Lin, Søren E. Pedersen, Aziz Sheikh, Arzu Yorgancioglu, Louis-Philippe Boulet

European Respiratory Journal 53 (6) 1901046; DOI: 10.1183/13993003.01046-2019 Published 27 June 2019
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The discovery of novel mechanisms for lymphangioleiomyomatosis pathogenesis through GWAS: a rarity in rare respiratory disorders
Arnold S. Kristof, Victor E. Ortega

European Respiratory Journal 53 (6) 1900863; DOI: 10.1183/13993003.00863-2019 Published 27 June 2019
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Surgery or stereotactic body radiotherapy for early-stage lung cancer: two sides of the same coin?
Lawek Berzenji, Paul E. Van Schil

European Respiratory Journal 53 (6) 1900711; DOI: 10.1183/13993003.00711-2019 Published 20 June 2019
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A journey to the centre of the mediastinal lymph nodes
Beatriz Amat, Sandra Sapia

European Respiratory Journal 53 (6) 1900850; DOI: 10.1183/13993003.00850-2019 Published 20 June 2019
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Towards precision medicine in bronchiectasis: what is the role of neutrophilic elastase determination?
Grace Oscullo Yepez, Jesus María Sierra-Párraga, Tomás Posadas Blazquez, Miguel Ángel Martínez-García

European Respiratory Journal 53 (6) 1900765; DOI: 10.1183/13993003.00765-2019 Published 13 June 2019
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The evolution of COPD species; or, something is changing for good in COPD
Joan B. Soriano

European Respiratory Journal 53 (6) 1900762; DOI: 10.1183/13993003.00762-2019 Published 27 June 2019
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New evidence on the chemoprevention of inhaled steroids and the risk of lung cancer in COPD
Luis M. Seijo, Joan B. Soriano, Germán Peces-Barba

European Respiratory Journal 53 (6) 1900717; DOI: 10.1183/13993003.00717-2019 Published 5 June 2019
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Pulmonary hypertension at high altitude
Robert Naeije

European Respiratory Journal 53 (6) 1900985; DOI: 10.1183/13993003.00985-2019 Published 27 June 2019
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Repurposing benzbromarone for pulmonary arterial hypertension: can channelling the past deliver the therapy of the future?
Anne L. Theilmann, Mark L. Ormiston

European Respiratory Journal 53 (6) 1900583; DOI: 10.1183/13993003.00583-2019 Published 5 June 2019

ERS Official Document

ERS statement
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  ERS statement on respiratory muscle testing at rest and during exercise
  Pierantonio Laveneziana, Andre Albuquerque, Andrea Aliverti, Tony Babb, Esther Barreiro, Martin Dres, Bruno-Pierre Dubé, Brigitte Fauroux, Joaquim Gea, Jordan A. Guenette, Anna L. Hudson, Hans-Joachim Kabitz, Franco Laghi, Daniel Langer, Yuan-Ming Luo, J. Alberto Neder, Denis O'Donnell, Michael I. Polkey, Roberto A. Rabinovich, Andrea Rossi, Frédéric Series, Thomas Similowski, Christina M. Spengler, Ioannis Vogiatzis, Samuel Verges
  
  European Respiratory Journal 53 (6) 1801214; DOI: 10.1183/13993003.01214-2018 Published 13 June 2019

WHO Consensus Document

Tuberculosis
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  Reducing tuberculosis transmission: a consensus document from the World Health Organization Regional Office for Europe
  Giovanni Battista Migliori, Edward Nardell, Askar Yedilbayev, Lia D'Ambrosio, Rosella Centis, Marina Tadolini, Martin van den Boom, Soudeh Ehsani, Giovanni Sotgiu, Masoud Dara
  
  European Respiratory Journal 53 (6) 1900391; DOI: 10.1183/13993003.00391-2019 Published 5 June 2019

Original Articles

Interstitial lung disease and rare lung disease
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  A genome-wide association study implicates NR2F2 in lymphangioleiomyomatosis pathogenesis
  Wonji Kim, Krinio Giannikou, John R. Dreier, Sanghun Lee, Magdalena E. Tyburczy, Edwin K. Silverman, Elżbieta Radzikowska, Shulin Wu, Chin-Lee Wu, Elizabeth P. Henske, Gary Hunninghake, Havi Carel, Antonio Roman, Miquel Angel Pujana, Joel Moss, Sungho Won, David J. Kwiatkowski
  
  European Respiratory Journal 53 (6) 1900329; DOI: 10.1183/13993003.00329-2019 Published 27 June 2019
Lung cancer
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  Surgery or radiotherapy for stage I lung cancer? An intention-to-treat analysis
  Katie L. Spencer, Martyn P.T. Kennedy, Katie L. Lummis, Deborah A.B. Ellames, Michael Snee, Alessandro Brunelli, Kevin Franks, Matthew E.J. Callister
  
  European Respiratory Journal 53 (6) 1801568; DOI: 10.1183/13993003.01568-2018 Published 20 June 2019
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  Video-assisted thoracic lobectomy versus stereotactic body radiotherapy for stage I nonsmall cell lung cancer in elderly patients: a propensity matched comparative analysis
  Deniece D.E.M.A. Detillon, Mieke J. Aarts, Katrien De Jaeger, Casper H.J. Van Eijck, Eelco J. Veen
  
  European Respiratory Journal 53 (6) 1801561; DOI: 10.1183/13993003.01561-2018 Published 20 June 2019
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  Needle-based confocal laser endomicroscopy for real-time diagnosing and staging of lung cancer
  Lizzy Wijmans, Joey Yared, Daniel M. de Bruin, Sybren L. Meijer, Paul Baas, Peter I. Bonta, Jouke T. Annema
  
  European Respiratory Journal 53 (6) 1801520; DOI: 10.1183/13993003.01520-2018 Published 20 June 2019
  
  Supplementary video
Bronchiectasis
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  A point-of-care neutrophil elastase activity assay identifies bronchiectasis severity, airway infection and risk of exacerbation
  Amelia Shoemark, Erin Cant, Luis Carreto, Alexandria Smith, Martina Oriano, Holly R. Keir, Lidia Perea, Elisabet Canto, Leonardo Terranova, Silvia Vidal, Kelly Moffitt, Stefano Aliberti, Oriol Sibila, James D. Chalmers
  
  European Respiratory Journal 53 (6) 1900303; DOI: 10.1183/13993003.00303-2019 Published 13 June 2019
  
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Asthma and allergy
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  Laboratory animal allergy is preventable in modern research facilities
  Johanna R. Feary, Susan J. Schofield, Jennifer Canizales, Bernadette Fitzgerald, James Potts, Meinir Jones, Paul Cullinan
  
  European Respiratory Journal 53 (6) 1900171; DOI: 10.1183/13993003.00171-2019 Published 20 June 2019
Asthma
- Open Access
  Tiotropium add-on therapy is safe and reduces seasonal worsening in paediatric asthma patients
  Christian Vogelberg, Stanley J. Szefler, Elianne J.L.E. Vrijlandt, Attilio L. Boner, Michael Engel, Georges El Azzi, Sebastian Dan Vulcu, Petra M. Moroni-Zentgraf, Olaf Eickmeier, Eckard H. Hamelmann
  
  European Respiratory Journal 53 (6) 1801824; DOI: 10.1183/13993003.01824-2018 Published 13 June 2019
COPD
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  Assessing global COPD awareness with Google Trends
  Anna Boehm, Alex Pizzini, Thomas Sonnweber, Judith Loeffler-Ragg, Claudia Lamina, Guenter Weiss, Ivan Tancevski
  
  European Respiratory Journal 53 (6) 1900351; DOI: 10.1183/13993003.00351-2019 Published 27 June 2019
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  Inhaled corticosteroids and the risk of lung cancer in COPD: a population-based cohort study
  Adam J.N. Raymakers, Mohsen Sadatsafavi, Don D. Sin, J. Mark FitzGerald, Carlo A. Marra, Larry D. Lynd
  
  European Respiratory Journal 53 (6) 1801257; DOI: 10.1183/13993003.01257-2018 Published 5 June 2019
Pulmonary hypertension
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  Pulmonary arterial pressure at rest and during exercise in chronic mountain sickness: a meta-analysis
  Rodrigo Soria, Matthias Egger, Urs Scherrer, Nicole Bender, Stefano F. Rimoldi
  
  European Respiratory Journal 53 (6) 1802040; DOI: 10.1183/13993003.02040-2018 Published 27 June 2019
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  Riociguat for treatment of pulmonary hypertension in COPD: a translational study
  Alexandra Pichl, Natascha Sommer, Mariola Bednorz, Michael Seimetz, Stefan Hadzic, Stefan Kuhnert, Simone Kraut, Elsa T. Roxlau, Baktybek Kojonazarov, Jochen Wilhelm, Marija Gredic, Henning Gall, Khodr Tello, Manuel J. Richter, Oleg Pak, Aleksandar Petrovic, Matthias Hecker, Ralph T. Schermuly, Friedrich Grimminger, Werner Seeger, Hossein A. Ghofrani, Norbert Weissmann
  
  European Respiratory Journal 53 (6) 1802445; DOI: 10.1183/13993003.02445-2018 Published 27 June 2019
- Open Access
  Obesity alters oestrogen metabolism and contributes to pulmonary arterial hypertension
  Kirsty M. Mair, Katie Y. Harvey, Alasdair D. Henry, Dianne Z. Hillyard, Margaret Nilsen, Margaret R. MacLean
  
  European Respiratory Journal 53 (6) 1801524; DOI: 10.1183/13993003.01524-2018 Published 13 June 2019
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  Targeting TMEM16A to reverse vasoconstriction and remodelling in idiopathic pulmonary arterial hypertension
  Rita Papp, Chandran Nagaraj, Diana Zabini, Bence M. Nagy, Miklós Lengyel, Davor Skofic Maurer, Neha Sharma, Bakytbek Egemnazarov, Gabor Kovacs, Grazyna Kwapiszewska, Leigh M. Marsh, Andelko Hrzenjak, Gerald Höfler, Miroslava Didiasova, Malgorzata Wygrecka, Laura K. Sievers, Peter Szucs, Péter Enyedi, Bahil Ghanim, Walter Klepetko, Horst Olschewski, Andrea Olschewski
  
  European Respiratory Journal 53 (6) 1800965; DOI: 10.1183/13993003.00965-2018 Published 5 June 2019
- Open Access
  Risk assessment in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension
  Marc Humbert, Harrison W. Farber, Hossein-Ardeschir Ghofrani, Raymond L. Benza, Dennis Busse, Christian Meier, Marius M. Hoeper
  
  European Respiratory Journal 53 (6) 1802004; DOI: 10.1183/13993003.02004-2018 Published 5 June 2019
Imaging
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  Ambient air pollution and pulmonary vascular volume on computed tomography: the MESA Air Pollution and Lung cohort studies
  Carrie P. Aaron, Eric A. Hoffman, Steven M. Kawut, John H.M. Austin, Matthew Budoff, Erin D. Michos, Karen Hinckley Stukovsky, Coralynn Sack, Adam A. Szpiro, Karol D. Watson, Joel D. Kaufman, R. Graham Barr
  
  European Respiratory Journal 53 (6) 1802116; DOI: 10.1183/13993003.02116-2018 Published 5 June 2019

Review

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Detection, survival and infectious potential of Mycobacterium tuberculosis in the environment: a review of the evidence and epidemiological implications
Leonardo Martinez, Renu Verma, Julio Croda, C. Robert Horsburgh Jr, Katharine S. Walter, Nicholas Degner, Keren Middelkoop, Anastasia Koch, Sabine Hermans, Digby F. Warner, Robin Wood, Frank Cobelens, Jason R. Andrews

European Respiratory Journal 53 (6) 1802302; DOI: 10.1183/13993003.02302-2018 Published 27 June 2019

Agora

Research letters
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  Regional differences in rate of FEV₁ decline in COPD: lessons from SUMMIT
  Bartolomé R. Celli, Julie A. Anderson, Robert D. Brook, Peter M.A. Calverley, Nicholas J. Cowans, Courtney Crim, Fernando Martinez, David E. Newby, Julie Yates, Jørgen Vestbo
  
  European Respiratory Journal 53 (6) 1900278; DOI: 10.1183/13993003.00278-2019 Published 27 June 2019
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  Impact of chest imaging quality on the diagnosis of the usual interstitial pneumonia pattern: a hub and spoke study
  Giacomo Sgalla, Anna Rita Larici, Antonina Re, Alessandra Farchione, Giuseppe Cicchetti, Lucio Calandriello, Alessia Comes, Nicoletta Golfi, Bruno Iovene, Francesco Varone, Riccardo Manfredi, Luca Richeldi
  
  European Respiratory Journal 53 (6) 1900084; DOI: 10.1183/13993003.00084-2019 Published 27 June 2019
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  Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux
  Jeanne-Marie Perotin, James P.R. Schofield, Susan J. Wilson, Jonathan Ward, Joost Brandsma, Fabio Strazzeri, Aruna Bansal, Xian Yang, Anthony Rowe, Julie Corfield, Rene Lutter, Dominick E. Shaw, Per S. Bakke, Massimo Caruso, Barbro Dahlén, Stephen J. Fowler, Ildikó Horváth, Peter Howarth, Norbert Krug, Paolo Montuschi, Marek Sanak, Thomas Sandström, Kai Sun, Ioannis Pandis, Charles Auffray, Bertrand De Meulder, Diane Lefaudeux, John H. Riley, Ana R. Sousa, Sven-Erik Dahlen, Ian M. Adcock, Kian Fan Chung, Peter J. Sterk, Paul J. Skipp, Jane E. Collins, Donna E. Davies, Ratko Djukanović on behalf of the U-BIOPRED Study Group
  
  European Respiratory Journal 53 (6) 1900453; DOI: 10.1183/13993003.00453-2019 Published 27 June 2019
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  Cancer prevalence is increased in females with sleep apnoea: data from the ESADA study
  Athanasia Pataka, Maria R. Bonsignore, Silke Ryan, Renata L. Riha, Jean-Louis Pepin, Sofia Schiza, Ozen K. Basoglu, Pawel Sliwinski, Ondrej Ludka, Paschalis Steiropoulos, Ulla Anttalainen, Walter T. McNicholas, Jan Hedner, Ludger Grote on behalf of the ESADA study group
  
  European Respiratory Journal 53 (6) 1900091; DOI: 10.1183/13993003.00091-2019 Published 20 June 2019
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  Physical activity and quality of life in patients with pulmonary hypertension
  Thomas M. Cascino, Vallerie V. McLaughlin, Caroline R. Richardson, Nilofar Behbahani-Nejad, Victor M. Moles, Scott H. Visovatti, Elizabeth A. Jackson
  
  European Respiratory Journal 53 (6) 1900028; DOI: 10.1183/13993003.00028-2019 Published 20 June 2019
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  Severe asthma with blood hypereosinophilia associated with JAK2 V617F mutation: a case series
  Laure Tabèze, Sylvain Marchand-Adam, Raphaël Borie, Aurélien Justet, Clairelyne Dupin, Marie-Christine Dombret, Bruno Crestani, Camille Taillé
  
  European Respiratory Journal 53 (6) 1802248; DOI: 10.1183/13993003.02248-2018 Published 13 June 2019
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  Differences in asthma control and lung function in relation to allergic status
  Chris RuiWen Kuo, Brian Lipworth
  
  European Respiratory Journal 53 (6) 1802102; DOI: 10.1183/13993003.02102-2018 Published 13 June 2019
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  Bone mineral density in cystic fibrosis patients using low-dose chest computed tomography: a pilot study
  Rubens Gabriel Feijó Andrade, Gabriele Carra Forte, Bruno Hochhegger, Leonardo Araujo Pinto
  
  European Respiratory Journal 53 (6) 1900066; DOI: 10.1183/13993003.00066-2019 Published 5 June 2019
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  A pilot study to test the feasibility of histological characterisation of asthma–COPD overlap
  Eleni Papakonstantinou, Spasenjia Savic, Aline Siebeneichler, Werner Strobel, Paul W. Jones, Michael Tamm, Daiana Stolz
  
  European Respiratory Journal 53 (6) 1801941; DOI: 10.1183/13993003.01941-2018 Published 5 June 2019
Correspondence
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  Explaining variation in the burden of child and adolescent tuberculosis
  Kathryn J. Snow, Susan M. Sawyer, Justin T. Denholm, Stephen M. Graham
  
  European Respiratory Journal 53 (6) 1901007; DOI: 10.1183/13993003.01007-2019 Published 27 June 2019
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  Artificial intelligence for pulmonary function test interpretation
  Sherif Gonem, Salman Siddiqui
  
  European Respiratory Journal 53 (6) 1900638; DOI: 10.1183/13993003.00638-2019 Published 5 June 2019
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  Artificial intelligence for pulmonary function test interpretation
  Marko Topalovic, Nilakash Das, Wim Janssens on behalf of the authors
  
  European Respiratory Journal 53 (6) 1900782; DOI: 10.1183/13993003.00782-2019 Published 5 June 2019
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  Correspondence on the debate regarding the haemodynamic definition of pulmonary hypertension
  Bradley A. Maron, Gaurav Choudhary, Ryan J. Tedford, Evan Brittain
  
  European Respiratory Journal 53 (6) 1900727; DOI: 10.1183/13993003.00727-2019 Published 5 June 2019

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Table of Contents

Editorials

ERS Official Document

ERS statement

WHO Consensus Document

Tuberculosis

Original Articles

Interstitial lung disease and rare lung disease

Lung cancer

Bronchiectasis

Asthma and allergy

Asthma

COPD

Pulmonary hypertension

Imaging

Review

Agora

Research letters

Correspondence

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