Extract
We previously published data in the European Respiratory Journal describing the return of obstructive sleep apnoea (OSA) following the withdrawal of continuous positive airway pressure (CPAP) [1]. In this study, about one third of patients did not experience a significant return of OSA by the fourth night without CPAP, as measured using the oxygen desaturation index (ODI). This suggested that CPAP need not be an every night therapy in some patients with OSA, although there was no clear way of identifying such patients in advance of the trial of CPAP withdrawal. Limitations to this study were discussed in the paper and correctly highlighted by van Zeller and Drummond [2].
Abstract
Following CPAP withdrawal, in some obstructive sleep apnoea patients, evidence of sleep fragmentation can occur prior to the appearance of significant oxygen desaturations http://ow.ly/OhoN30o957o
Footnotes
Conflict of interest: C. Turnbull reports personal fees for consultancy from Bayer, outside the submitted work.
Conflict of interest: S. Pattenden has nothing to disclose.
Conflict of interest: T. Gaisl reports personal fees from Bayer AG (consultancy), outside the submitted work.
Conflict of interest: V. Rossi has nothing to disclose.
Conflict of interest: S. Thiel has nothing to disclose.
Conflict of interest: M. Kohler reports grants from Swiss National Science Foundation, during the conduct of the study; grants and personal fees from Bayer, outside the submitted work.
Conflict of interest: J. Stradling reports grants from Oxford Hospitals Charitable Funds, during the conduct of the study; grants and personal fees from Bayer, personal fees from ResMed UK, outside the submitted work.
Support statement: This work was supported by the Oxford Hospitals Charitable Funds and Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung. Funding information for this article has been deposited with the Crossref Funder Registry.
- Received December 12, 2018.
- Accepted February 1, 2019.
- Copyright ©ERS 2019
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