Table of Contents

Original Articles

• Airways disease and basic science

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    Eosinophil-derived IL-13 promotes emphysema

    Alfred D. Doyle, Manali Mukherjee, William E. LeSuer, Tyler B. Bittner, Saif M. Pasha, Justin J. Frere, Joseph L. Neely, Jake A. Kloeber, Kelly P. Shim, Sergei I. Ochkur, Terence Ho, Sarah Svenningsen, Benjamin L. Wright, Matthew A. Rank, James J. Lee, Parameswaran Nair, Elizabeth A. Jacobsen

    European Respiratory Journal 53 (5) 1801291; DOI: 10.1183/13993003.01291-2018 Published 30 May 2019

• COPD

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    Oxygen compared to air during exercise training in COPD with exercise-induced desaturation

    Jennifer A. Alison, Zoe J. McKeough, Regina W.M. Leung, Anne E. Holland, Kylie Hill, Norman R. Morris, Sue Jenkins, Lissa M. Spencer, Catherine J. Hill, Annemarie L. Lee, Helen Seale, Nola Cecins, Christine F. McDonald

    European Respiratory Journal 53 (5) 1802429; DOI: 10.1183/13993003.02429-2018 Published 30 May 2019
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    CRP-guided antibiotic treatment in acute exacerbations of COPD in hospital admissions

    H.J. Prins, Ruud Duijkers, Paul van der Valk, Marianne Schoorl, Johannes M.A. Daniels, Tjip S. van der Werf, Wim G. Boersma

    European Respiratory Journal 53 (5) 1802014; DOI: 10.1183/13993003.02014-2018 Published 23 May 2019

• Sleep medicine

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    Randomised controlled trial of polysomnographic titration of noninvasive ventilation

    Liam M. Hannan, Linda Rautela, David J. Berlowitz, Christine F. McDonald, Jennifer M. Cori, Nicole Sheers, Caroline Chao, Fergal J. O'Donoghue, Mark E. Howard

    European Respiratory Journal 53 (5) 1802118; DOI: 10.1183/13993003.02118-2018 Published 23 May 2019

• Asthma

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    Asthma and affective traits in adults: a genetically informative study

    Kelli Lehto, Nancy L. Pedersen, Catarina Almqvist, Yi Lu, Bronwyn K. Brew

    European Respiratory Journal 53 (5) 1802142; DOI: 10.1183/13993003.02142-2018 Published 30 May 2019
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    Dampness, mould, onset and remission of adult respiratory symptoms, asthma and rhinitis

    Juan Wang, Mihkel Pindus, Christer Janson, Torben Sigsgaard, Jeong-Lim Kim, Mathias Holm, Johan Sommar, Hans Orru, Thorarinn Gislason, Ane Johannessen, Randi J. Bertelsen, Dan Norbäck

    European Respiratory Journal 53 (5) 1801921; DOI: 10.1183/13993003.01921-2018 Published 23 May 2019
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    Inadequate assessment of adherence to maintenance medication leads to loss of power and increased costs in trials of severe asthma therapy: results from a systematic literature review and modelling study

    Matshediso C. Mokoka, Melissa J. McDonnell, Elaine MacHale, Breda Cushen, Fiona Boland, Sarah Cormican, Christina Doherty, Frank Doyle, Richard W. Costello, Garrett Greene

    European Respiratory Journal 53 (5) 1802161; DOI: 10.1183/13993003.02161-2018 Published 18 May 2019
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    Prescribed analgesics in pregnancy and risk of childhood asthma

    Seif O. Shaheen, Cecilia Lundholm, Bronwyn K. Brew, Catarina Almqvist

    European Respiratory Journal 53 (5) 1801090; DOI: 10.1183/13993003.01090-2018 Published 18 May 2019
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    Transcriptomics of atopy and atopic asthma in white blood cells from children and adolescents

    Yale Jiang, Olena Gruzieva, Ting Wang, Erick Forno, Nadia Boutaoui, Tao Sun, Simon K. Merid, Edna Acosta-Pérez, Inger Kull, Glorisa Canino, Josep M. Antó, Jean Bousquet, Erik Melén, Wei Chen, Juan C. Celedón

    European Respiratory Journal 53 (5) 1900102; DOI: 10.1183/13993003.00102-2019 Published 18 May 2019

• Basic science

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    Exaggerated BMP4 signalling alters human airway basal progenitor cell differentiation to cigarette smoking-related phenotypes

    Wu-Lin Zuo, Jing Yang, Yael Strulovici-Barel, Jacqueline Salit, Mahboubeh Rostami, Jason G. Mezey, Sarah L. O'Beirne, Robert J. Kaner, Ronald G. Crystal

    European Respiratory Journal 53 (5) 1702553; DOI: 10.1183/13993003.02553-2017 Published 18 May 2019

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• Pulmonary hypertension

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    Traffic exposures, air pollution and outcomes in pulmonary arterial hypertension: a UK cohort study analysis

    Eleni Sofianopoulou, Stephen Kaptoge, Stefan Gräf, Charaka Hadinnapola, Carmen M. Treacy, Colin Church, Gerry Coghlan, J. Simon R. Gibbs, Matthias Haimel, Luke S. Howard, Martin Johnson, David G. Kiely, Allan Lawrie, James Lordan, Robert V. MacKenzie Ross, Jennifer M. Martin, Shahin Moledina, Michael Newnham, Andrew J. Peacock, Laura C. Price, Christopher J. Rhodes, Jay Suntharalingam, Emilia M. Swietlik, Mark R. Toshner, John Wharton, Martin R. Wilkins, Stephen J. Wort, Joanna Pepke-Zaba, Robin Condliffe, Paul A. Corris, Emanuele Di Angelantonio, Steeve Provencher, Nicholas W. Morrell

    European Respiratory Journal 53 (5) 1801429; DOI: 10.1183/13993003.01429-2018 Published 30 May 2019
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    French experience of balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension

    Philippe Brenot, Xavier Jaïs, Yu Taniguchi, Carlos Garcia Alonso, Benoit Gerardin, Sacha Mussot, Olaf Mercier, Dominique Fabre, Florence Parent, Mitja Jevnikar, David Montani, Laurent Savale, Olivier Sitbon, Elie Fadel, Marc Humbert, Gérald Simonneau

    European Respiratory Journal 53 (5) 1802095; DOI: 10.1183/13993003.02095-2018 Published 18 May 2019
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    Pulmonary arterial hypertension associated with protein kinase inhibitors: a pharmacovigilance–pharmacodynamic study

    Lucie Cornet, Charles Khouri, Matthieu Roustit, Christophe Guignabert, Marie-Camille Chaumais, Marc Humbert, Bruno Revol, Fabien Despas, David Montani, Jean-Luc Cracowski

    European Respiratory Journal 53 (5) 1802472; DOI: 10.1183/13993003.02472-2018 Published 9 May 2019

• Lung cancer

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    Centrally located lung cancer and risk of occult nodal disease: an objective evaluation of multiple definitions of tumour centrality with dedicated imaging software

    Roberto F. Casal, Boris Sepesi, Ala-Eddin S. Sagar, Juerg Tschirren, Minxing Chen, Liang Li, Jennifer Sunny, Joyce Williams, Horiana B. Grosu, George A. Eapen, Carlos A. Jimenez, David E. Ost

    European Respiratory Journal 53 (5) 1802220; DOI: 10.1183/13993003.02220-2018 Published 9 May 2019

• Interstitial lung disease

  • Open Access

    Nationwide cloud-based integrated database of idiopathic interstitial pneumonias for multidisciplinary discussion

    Tomoyuki Fujisawa, Kazutaka Mori, Masashi Mikamo, Takashi Ohno, Kensuke Kataoka, Chikatoshi Sugimoto, Hideya Kitamura, Noriyuki Enomoto, Ryoko Egashira, Hiromitsu Sumikawa, Tae Iwasawa, Shoichiro Matsushita, Hiroaki Sugiura, Mikiko Hashisako, Tomonori Tanaka, Yasuhiro Terasaki, Shinobu Kunugi, Masashi Kitani, Ryo Okuda, Yasuoki Horiike, Yasunori Enomoto, Hideki Yasui, Hironao Hozumi, Yuzo Suzuki, Yutaro Nakamura, Junya Fukuoka, Takeshi Johkoh, Yasuhiro Kondoh, Takashi Ogura, Yoshikazu Inoue, Yoshinori Hasegawa, Naohiko Inase, Sakae Homma, Takafumi Suda

    European Respiratory Journal 53 (5) 1802243; DOI: 10.1183/13993003.02243-2018 Published 18 May 2019
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    Patient-reported distress can aid clinical decision-making in idiopathic pulmonary fibrosis: analysis of the PROFILE cohort

    Iain Stewart, Tricia McKeever, Rebecca Braybrooke, Eunice Oballa, Juliet K. Simpson, Toby M. Maher, Richard P. Marshall, Pauline T. Lukey, William A. Fahy, Gisli Jenkins, Gauri Saini

    European Respiratory Journal 53 (5) 1801925; DOI: 10.1183/13993003.01925-2018 Published 9 May 2019

• Cough

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    Impaired cough suppression in chronic refractory cough

    Peter S.P. Cho, Hannah V. Fletcher, Richard D. Turner, Caroline J. Jolley, Surinder S. Birring

    European Respiratory Journal 53 (5) 1802203; DOI: 10.1183/13993003.02203-2018 Published 2 May 2019

• Cystic fibrosis

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    Hyperpolarised ¹²⁹Xe magnetic resonance imaging to monitor treatment response in children with cystic fibrosis

    Jonathan H. Rayment, Marcus J. Couch, Nancy McDonald, Nikhil Kanhere, David Manson, Giles Santyr, Felix Ratjen

    European Respiratory Journal 53 (5) 1802188; DOI: 10.1183/13993003.02188-2018 Published 2 May 2019
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    Quantitative multivolume proton-magnetic resonance imaging in patients with cystic fibrosis lung disease: comparison with clinical indicators

    Francesca Pennati, Caterina Salito, Irene Borzani, Giulia Cervellin, Simone Gambazza, Riccardo Guarise, Maria Chiara Russo, Carla Colombo, Andrea Aliverti

    European Respiratory Journal 53 (5) 1702020; DOI: 10.1183/13993003.02020-2017 Published 2 May 2019

• Paediatrics

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    Xenon-129 MRI detects ventilation deficits in paediatric stem cell transplant patients unable to perform spirometry

    Laura L. Walkup, Kasiani Myers, Javier El-Bietar, Adam Nelson, Matthew M. Willmering, Michael Grimley, Stella M. Davies, Christopher Towe, Jason C. Woods

    European Respiratory Journal 53 (5) 1801779; DOI: 10.1183/13993003.01779-2018 Published 2 May 2019