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Table of Contents

01 April 2019; volume 53, issue 4

Editorials

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    The pulmonary haemodynamics during exercise – research network (PEX-NET) ERS Clinical Research Collaboration: investigating the prognostic relevance of exercise haemodynamics
    Gabor Kovacs, Philippe Herve, Horst Olschewski on behalf of the PEX-NET Clinical Research Collaboration
    European Respiratory Journal 53 (4) 1900458; DOI: 10.1183/13993003.00458-2019 Published 11 April 2019
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    Is it time to move away from short-acting beta-agonists in asthma management?
    Matthew J. Martin, Tim W. Harrison
    European Respiratory Journal 53 (4) 1802223; DOI: 10.1183/13993003.02223-2018 Published 4 April 2019
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    Improvements in air quality: whose lungs benefit?
    Ulrike Gehring, Gerard H. Koppelman
    European Respiratory Journal 53 (4) 1900365; DOI: 10.1183/13993003.00365-2019 Published 25 April 2019
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    Delivering high value therapies in COPD: the secret is in the marketing
    Helen Ashdown, Michael Steiner
    European Respiratory Journal 53 (4) 1900215; DOI: 10.1183/13993003.00215-2019 Published 25 April 2019
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    MicroRNAs in COPD: small molecules with big potential
    Brian D. Hobbs, Kelan G. Tantisira
    European Respiratory Journal 53 (4) 1900515; DOI: 10.1183/13993003.00515-2019 Published 25 April 2019
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    The Medusa faces of dyspnoea in COPD
    Emiel F.M. Wouters
    European Respiratory Journal 53 (4) 1900487; DOI: 10.1183/13993003.00487-2019 Published 18 April 2019
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    Exercising our options: comparing effects of exercise and positive expiratory pressure on mucociliary clearance
    Scott H. Donaldson
    European Respiratory Journal 53 (4) 1900510; DOI: 10.1183/13993003.00510-2019 Published 18 April 2019
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    Protecting those who serve: are we doing enough to prevent tuberculosis in healthcare workers?
    Jennifer Furin, Giovanni Sotgiu
    European Respiratory Journal 53 (4) 1900485; DOI: 10.1183/13993003.00485-2019 Published 18 April 2019
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    Predicting respiratory failure in amyotrophic lateral sclerosis: recruiting a few good pulmonologists
    Noah Lechtzin
    European Respiratory Journal 53 (4) 1900360; DOI: 10.1183/13993003.00360-2019 Published 18 April 2019
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    Electronic clinical decision support system (eCDSS) in the management of asthma: from theory to practice
    Jean Bousquet
    European Respiratory Journal 53 (4) 1900339; DOI: 10.1183/13993003.00339-2019 Published 25 April 2019
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    The unknown pathophysiological relevance of right ventricular hypertrophy in pulmonary arterial hypertension
    Frances S. de Man, M. Louis Handoko, Anton Vonk-Noordegraaf
    European Respiratory Journal 53 (4) 1900255; DOI: 10.1183/13993003.00255-2019 Published 4 April 2019

Original Articles

  • Environment and the lung

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      Benefits of improved air quality on ageing lungs: impacts of genetics and obesity
      Anke Hüls, Dorothee Sugiri, Michael J. Abramson, Barbara Hoffmann, Holger Schwender, Katja Ickstadt, Ursula Krämer, Tamara Schikowski
      European Respiratory Journal 53 (4) 1801780; DOI: 10.1183/13993003.01780-2018 Published 25 April 2019
  • COPD

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      Interdisciplinary COPD intervention in primary care: a cluster randomised controlled trial
      Jenifer Liang, Michael J. Abramson, Grant Russell, Anne E. Holland, Nicholas A. Zwar, Billie Bonevski, Ajay Mahal, Paula Eustace, Eldho Paul, Kirsten Phillips, Narelle S. Cox, Sally Wilson, Johnson George
      European Respiratory Journal 53 (4) 1801530; DOI: 10.1183/13993003.01530-2018 Published 25 April 2019
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      Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD
      Alen Faiz, Katrina Steiling, Mirjam P. Roffel, Dirkje S. Postma, Avrum Spira, Marc E. Lenburg, Malte Borggrewe, Tim R. Eijgenraam, Marnix R. Jonker, Gerard H. Koppelman, Simon D. Pouwels, Gang Liu, Yuriy O. Alekseyev, Stephen Lam, Pieter S. Hiemstra, Peter J. Sterk, Wim Timens, Corry-Anke Brandsma, Irene H. Heijink, Maarten van den Berge
      European Respiratory Journal 53 (4) 1801202; DOI: 10.1183/13993003.01202-2018 Published 25 April 2019
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      Exercise intolerance in comorbid COPD and heart failure: the role of impaired aerobic function
      Alcides Rocha, Flavio F. Arbex, Priscila A. Sperandio, Frederico Mancuso, Mathieu Marillier, Anne-Catherine Bernard, Maria Clara N. Alencar, Denis E. O'Donnell, J. Alberto Neder
      European Respiratory Journal 53 (4) 1802386; DOI: 10.1183/13993003.02386-2018 Published 18 April 2019
  • Cystic fibrosis

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      Effects of exercise and airway clearance (positive expiratory pressure) on mucus clearance in cystic fibrosis: a randomised crossover trial
      Tiffany J. Dwyer, Evangelia Daviskas, Rahizan Zainuldin, Jordan Verschuer, Stefan Eberl, Peter T.P. Bye, Jennifer A. Alison
      European Respiratory Journal 53 (4) 1801793; DOI: 10.1183/13993003.01793-2018 Published 18 April 2019
  • Tuberculosis

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      Latent tuberculosis infection in healthcare workers in low- and middle-income countries: an updated systematic review
      Lika Apriani, Susan McAllister, Katrina Sharples, Bachti Alisjahbana, Rovina Ruslami, Philip C. Hill, Dick Menzies
      European Respiratory Journal 53 (4) 1801789; DOI: 10.1183/13993003.01789-2018 Published 18 April 2019
  • Interstitial lung disease

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      Telomere length and genetic variant associations with interstitial lung disease progression and survival
      Chad A. Newton, Justin M. Oldham, Brett Ley, Vikram Anand, Ayodeji Adegunsoye, Gabrielle Liu, Kiran Batra, Jose Torrealba, Julia Kozlitina, Craig Glazer, Mary E. Strek, Paul J. Wolters, Imre Noth, Christine Kim Garcia
      European Respiratory Journal 53 (4) 1801641; DOI: 10.1183/13993003.01641-2018 Published 11 April 2019
  • Lung structure and function

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      Artificial intelligence outperforms pulmonologists in the interpretation of pulmonary function tests
      Marko Topalovic, Nilakash Das, Pierre-Régis Burgel, Marc Daenen, Eric Derom, Christel Haenebalcke, Rob Janssen, Huib A.M. Kerstjens, Giuseppe Liistro, Renaud Louis, Vincent Ninane, Christophe Pison, Marc Schlesser, Piet Vercauter, Claus F. Vogelmeier, Emiel Wouters, Jokke Wynants, Wim Janssens on behalf of the Pulmonary Function Study Investigators
      European Respiratory Journal 53 (4) 1801660; DOI: 10.1183/13993003.01660-2018 Published 11 April 2019
  • Respiratory clinical practice

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      Development of a prognostic model of respiratory insufficiency or death in amyotrophic lateral sclerosis
      Jason Ackrivo, John Hansen-Flaschen, E. Paul Wileyto, Richard J. Schwab, Lauren Elman, Steven M. Kawut
      European Respiratory Journal 53 (4) 1802237; DOI: 10.1183/13993003.02237-2018 Published 18 April 2019
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      Exhaled air dispersion during high-flow nasal cannula therapy versus CPAP via different masks
      David S. Hui, Benny K. Chow, Thomas Lo, Owen T.Y. Tsang, Fanny W. Ko, Susanna S. Ng, Tony Gin, Matthew T.V. Chan
      European Respiratory Journal 53 (4) 1802339; DOI: 10.1183/13993003.02339-2018 Published 11 April 2019
  • Basic science and asthma

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      IL-17F, rather than IL-17A, underlies airway inflammation in a steroid-insensitive toluene diisocyanate-induced asthma model
      Rongchang Chen, Qingling Zhang, Shuyu Chen, Haixiong Tang, Peikai Huang, Shushan Wei, Zhenyu Liang, Xin Chen, Ailin Tao, Lihong Yao
      European Respiratory Journal 53 (4) 1801510; DOI: 10.1183/13993003.01510-2018 Published 4 April 2019
  • Asthma

    • Open Access
      The Electronic Asthma Management System (eAMS) improves primary care asthma management
      Samir Gupta, Courtney Price, Gina Agarwal, David Chan, Sanjeev Goel, Louis-Philippe Boulet, Alan G. Kaplan, Gerald Lebovic, Muhammad Mamdani, Sharon E. Straus
      European Respiratory Journal 53 (4) 1802241; DOI: 10.1183/13993003.02241-2018 Published 25 April 2019
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      Dynamic hyperinflation impairs daily life activity in asthma
      Akke-Nynke van der Meer, Kim de Jong, Aranka Hoekstra-Kuik, Elisabeth H. Bel, Anneke ten Brinke
      European Respiratory Journal 53 (4) 1801500; DOI: 10.1183/13993003.01500-2018 Published 11 April 2019
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      Changing prevalence of current asthma and inhaled corticosteroid treatment in the UK: population-based cohort 2006–2016
      Chloe I. Bloom, Sejal Saglani, Johanna Feary, Debbie Jarvis, Jennifer K. Quint
      European Respiratory Journal 53 (4) 1802130; DOI: 10.1183/13993003.02130-2018 Published 4 April 2019
  • Paediatrics and asthma

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      Newborn DNA-methylation, childhood lung function, and the risks of asthma and COPD across the life course
      Herman T. den Dekker, Kimberley Burrows, Janine F. Felix, Lucas A. Salas, Ivana Nedeljkovic, Jin Yao, Sheryl L. Rifas-Shiman, Carlos Ruiz-Arenas, N. Amin, Mariona Bustamante, Dawn L. DeMeo, A. John Henderson, Caitlin G. Howe, Marie-France Hivert, M. Arfan Ikram, Johan C. de Jongste, Lies Lahousse, Pooja R. Mandaviya, Joyce B. van Meurs, Mariona Pinart, Gemma C. Sharp, Lisette Stolk, André G. Uitterlinden, Josep M. Anto, Augusto A. Litonjua, Carrie V. Breton, Guy G. Brusselle, Jordi Sunyer, George Davey Smith, Caroline L. Relton, Vincent W.V. Jaddoe, Liesbeth Duijts
      European Respiratory Journal 53 (4) 1801795; DOI: 10.1183/13993003.01795-2018 Published 4 April 2019
  • Rare lung diseases

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      Analysis of the MILES cohort reveals determinants of disease progression and treatment response in lymphangioleiomyomatosis
      Nishant Gupta, Hye-Seung Lee, Lisa R. Young, Charlie Strange, Joel Moss, Lianne G. Singer, Koh Nakata, Alan F. Barker, Jeffrey T. Chapman, Mark L. Brantly, James M. Stocks, Kevin K. Brown, Joseph P. Lynch 3rd, Hilary J. Goldberg, Gregory P. Downey, Angelo M. Taveira-DaSilva, Jeffrey P. Krischer, Kenneth Setchell, Bruce C. Trapnell, Yoshikazu Inoue, Francis X. McCormack for the NIH Rare Lung Disease Consortium
      European Respiratory Journal 53 (4) 1802066; DOI: 10.1183/13993003.02066-2018 Published 4 April 2019

Series

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    Introduction to precision medicine in COPD
    Janice M. Leung, Ma'en Obeidat, Mohsen Sadatsafavi, Don D. Sin
    European Respiratory Journal 53 (4) 1802460; DOI: 10.1183/13993003.02460-2018 Published 11 April 2019

Agora

  • Research letters

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      Of the need to reconcile discrepancies between two different reference equations for combined single-breath DLNO–DLCO in systemic sclerosis
      Thomas Radtke, Thông Hua-Huy, Holger Dressel, Anh Tuan Dinh-Xuan
      European Respiratory Journal 53 (4) 1802109; DOI: 10.1183/13993003.02109-2018 Published 25 April 2019
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      Cytomegalovirus: an unrecognised potential contributor to cystic fibrosis disease progression?
      Michael D. Parkins, Kathleen J. Ramos, Christopher H. Goss, Ranjani Somayaji
      European Respiratory Journal 53 (4) 1801727; DOI: 10.1183/13993003.01727-2018 Published 25 April 2019
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      Extracorporeal membrane oxygenation and surgical embolectomy for high-risk pulmonary embolism
      Fabio Ius, Marius M. Hoeper, Christine Fegbeutel, Christian Kühn, Karen Olsson, Nurbol Koigeldiyev, Igor Tudorache, Gregor Warnecke, Jörg Optenhöfel, Jakob Ono Puntigam, Andreas Schäfer, Bernhard C. Meyer, Jan B. Hinrichs, Johann Bauersachs, Axel Haverich, Serghei Cebotari
      European Respiratory Journal 53 (4) 1801773; DOI: 10.1183/13993003.01773-2018 Published 25 April 2019
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      Levofloxacin pharmacokinetics, pharmacodynamics and outcome in multidrug-resistant tuberculosis patients
      Samiksha Ghimire, Bhagwan Maharjan, Erwin M. Jongedijk, Jos G.W. Kosterink, Gokarna R. Ghimire, Daan J. Touw, Tjip S. van der Werf, Bhabana Shrestha, Jan-Willem C. Alffenaar
      European Respiratory Journal 53 (4) 1802107; DOI: 10.1183/13993003.02107-2018 Published 18 April 2019
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      Therapeutic effects of nintedanib are not influenced by emphysema in the INPULSIS trials
      Vincent Cottin, Arata Azuma, Ganesh Raghu, Wibke Stansen, Susanne Stowasser, Rozsa Schlenker-Herceg, Martin Kolb
      European Respiratory Journal 53 (4) 1801655; DOI: 10.1183/13993003.01655-2018 Published 18 April 2019
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      Transcutaneous carbon dioxide measurement is not a reliable alternative to arterial blood gas sampling in the acute medical setting
      Victoria Mummery, Eleanor Rogers, Vijay Padmanaban, Dionne Matthew, Thomas Woodcock, Susannah Bloch
      European Respiratory Journal 53 (4) 1801726; DOI: 10.1183/13993003.01726-2018 Published 11 April 2019
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      The clinical impact of Pseudomonas aeruginosa eradication in bronchiectasis in a Dutch referral centre
      Angelina Pieters, Marleen Bakker, Rogier A.S. Hoek, Josje Altenburg, Mireille van Westreenen, Joachim G.J.V. Aerts, Menno M. van der Eerden
      European Respiratory Journal 53 (4) 1802081; DOI: 10.1183/13993003.02081-2018 Published 11 April 2019
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      Ventricular mass as a prognostic imaging biomarker in incident pulmonary arterial hypertension
      Catherine E. Simpson, Rachel L. Damico, Todd M. Kolb, Stephen C. Mathai, Rubina M. Khair, Takahiro Sato, Khalil Bourji, Ryan J. Tedford, Stefan L. Zimmerman, Paul M. Hassoun
      European Respiratory Journal 53 (4) 1802067; DOI: 10.1183/13993003.02067-2018 Published 4 April 2019
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      Neutrophil extracellular traps in ex vivo lung perfusion perfusate predict the clinical outcome of lung transplant recipients
      Lindsay Caldarone, Andrea Mariscal, Andrew Sage, Meraj Khan, Stephen Juvet, Tereza Martinu, Ricardo Zamel, Marcelo Cypel, Mingyao Liu, Nades Palaniyar, Shaf Keshavjee
      European Respiratory Journal 53 (4) 1801736; DOI: 10.1183/13993003.01736-2018 Published 4 April 2019
  • Correspondence

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      The importance of differentiating behavioural and psychological treatment effects from placebo in respiratory interventions
      Ben Ainsworth, Doug Hardman, Mike Thomas
      European Respiratory Journal 53 (4) 1900156; DOI: 10.1183/13993003.00156-2019 Published 25 April 2019
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      Triple therapy for all patients with severe symptomatic COPD at risk of exacerbations
      Alberto Papi, Stefano Petruzzelli, Stefano Vezzoli, George Georges, Leonardo M. Fabbri
      European Respiratory Journal 53 (4) 1900147; DOI: 10.1183/13993003.00147-2019 Published 18 April 2019
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      Triple therapy in COPD: only for the right patient
      Samy Suissa, Amnon Ariel
      European Respiratory Journal 53 (4) 1900394; DOI: 10.1183/13993003.00394-2019 Published 18 April 2019
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      Asthma paradoxes: time for a new approach across the spectrum of asthma severity
      Luis J. Nannini
      European Respiratory Journal 53 (4) 1802329; DOI: 10.1183/13993003.02329-2018 Published 4 April 2019
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      Asthma paradoxes: time for a new approach across the spectrum of asthma severity
      Richard Beasley, Grace Bird, James Harper, Mark Weatherall
      European Respiratory Journal 53 (4) 1900218; DOI: 10.1183/13993003.00218-2019 Published 4 April 2019
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European Respiratory Journal: 53 (4)
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