Wejse 2009 [14] | LC-MS/MS | 77.7±23.2 (35–191) | 0/232 (0.0) | 8 months | Clinical score | ND | 0, 2, 4, 6, 8 weeks, 5, 8 months |
Martineau 2011 [12] | LC-MS/MS | 20.7±19.1 (UD–94) | 96/135 (71.1) | 8 weeks | Sputum culture conversion | 0, 2, 4, 6, 8 weeks | 0, 2, 4, 6, 8 weeks |
Salahuddin 2013 [9] | ECLIA | 54.2±23.7 (10–135) | 36/259 (13.9) | 12 weeks | Weight gain and chest radiograph involvement (co-primary) | ND | 0, 4, 8, 12 weeks |
Ralph 2013 [15] | NA | ND | ND | 24 weeks | Sputum culture conversion and clinical score (co-primary) | 0, 4, 8 weeks | 0, 1, 2, 3, 4, 5, 6, 7, 8, 12, 16, 20, 24 weeks |
Mily 2015 [10] | ECLIA | 26.7±16.3 (8–91) | 142/256 (55.5) | 24 weeks | Sputum culture conversion and clinical score (co-primary) | 0, 4, 8 weeks | 0, 1, 2, 3, 4, 6, 8, 10, 12, 24 weeks |
Daley 2015 [16] | ECLIA | 63.0±49.7 (10–250) | 34/204 (16.7) | 8 weeks | Sputum culture conversion | 0, 2, 4, 6, 8 weeks | 0, 2, 4, 6, 8 weeks |
Tukvadze 2015 [17] | LC-MS/MS | 37.4±22.1 (6–104) | 69/190 (36.3) | 16 weeks | Sputum culture conversion | 0, 2, 4, 6, 8, 12, 16 weeks | 0, 8 weeks |
Ganmaa 2017 [13] | CLIA | 17.2±24.2 (UD–188) | 311/384 (81.0) | 8 weeks | Sputum culture conversion | 0, 2, 4, 6, 8 weeks | 0, 2, 4, 6, 8 weeks |