Abstract
Pulmonary tuberculosis (PTB) is one of the most common infectious diseases worldwide. Despite availability of effective treatment, a significant number of patients suffer from permanent lung damage. This study aims to assess predictive factors of chronic sequelae in patients treated for PTB. A retrospective comparative analysis was conducted in a tertiary care hospital of Tunis from January 2014 to December 2016. Patients treated for PTB were included. Patients with PTB treatment failure, retreatment cases, multidrug PTB and patients having other chronic lung conditions were excluded. All patients had Chest X-Ray at the beginning and the end of PTB treatment and 6 months after recovery. Data were analyzed 6 months after PTB recovery. Patients were classified, according to the severity of PTB squeale in two groups (G1= none or limited sequeale; G2= moderate and advanced sequeale). During the study period 88 patients (mean age = 39.7 ± 17.3 years; 76% male) were included (G1, n=43; G2, n=45). Main radiological sequaele in G2 were: parenchymal scarring (43.2%), pulmonary fibrosis (13.6%) and bronchiectasis (9%). G2 patients had higher smoking (p=0.05), were more often ethylic and had more diabetes (p>0.05). Patients of G2 were older (p=0.05), consulted later (p>0.05) and were more dyspneic (p=0.01). Recovery delay was the same in both groups. Smoking, alcoholism and male gender are predictive factors to the sequeale of PTB. Parenchymal scarring and bronchiectasis were the most common pulmonary sequeale. Thus, in addition to antituberculous treatment, smoking cessation is an essential measure to reduce the risk of complications.
Footnotes
Cite this article as: European Respiratory Journal 2018 52: Suppl. 62, PA2744.
This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).
- Copyright ©the authors 2018