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Reduced environmental impact of a reusable soft mist inhaler

Michaela Hänsel, Thomas Bambach, Herbert Wachtel
European Respiratory Journal 2018 52: PA1021; DOI: 10.1183/13993003.congress-2018.PA1021
Michaela Hänsel
1TA Respiratory/Biosimilars, Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany
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Thomas Bambach
2Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany
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Herbert Wachtel
3Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim am Rhein, Germany
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Abstract

Introduction: Pressurised metered-dose inhalers (pMDIs) use a hydrofluoroalkane (HFA) propellant, a greenhouse gas with a high global warming potential. Soft mist inhalers (Respimat®) are propellant-free and potentially reusable, reducing their environmental impact.

Aims: Compare product carbon footprints (PCFs) of disposable Respimat and HFA pMDI devices, and assess any environmental impact of a reusable Respimat device supplied with 3 or 6 months of refills.

Methods: Whole life-cycle PCFs of tiotropium bromide (Spiriva®) Respimat, ipratropium bromide/fenoterol hydrobromide (Berodual®) Respimat, Berodual® HFA pMDI and ipratropium bromide (Atrovent®) HFA pMDI were assessed. Data were collected from relevant supply chain members using customised data collection email templates. PCFs were calculated according to the Intergovernmental Panel on Climate Change Fifth Assessment Report (IPCC AR5).

Results: pMDI PCFs are ~20 times greater than disposable propellant-free Respimat PCFs (~98% due to HFA release during use and end-of-life phases). Electricity and thermal energy use in a disposable Respimat device assembly adds more to the PCF than cartridge assembly: 0.38 vs 0.08 kg CO2eq. Therefore, developing a reusable Respimat device has potential to further reduce PCF. Indeed, assessment of a reusable Respimat shows a further reduction in PCF by 57% for a 3-month refill and 71% for a 6-month refill, vs the 1-month disposable Respimat.

Conclusions: Respimat not only addresses many practical limitations of pMDIs but also has a considerably lower environmental impact than HFA pMDIs. Development of a reusable option decreases impact even further, providing significant environmental improvements.

Footnotes

Cite this article as: European Respiratory Journal 2018 52: Suppl. 62, PA1021.

This is an ERS International Congress abstract. No full-text version is available. Further material to accompany this abstract may be available at www.ers-education.org (ERS member access only).

  • Copyright ©the authors 2018
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Reduced environmental impact of a reusable soft mist inhaler
Michaela Hänsel, Thomas Bambach, Herbert Wachtel
European Respiratory Journal Sep 2018, 52 (suppl 62) PA1021; DOI: 10.1183/13993003.congress-2018.PA1021

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Reduced environmental impact of a reusable soft mist inhaler
Michaela Hänsel, Thomas Bambach, Herbert Wachtel
European Respiratory Journal Sep 2018, 52 (suppl 62) PA1021; DOI: 10.1183/13993003.congress-2018.PA1021
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