European Respiratory Journal: 52 (6)

01 December 2018; volume 52, issue 6

Editorials

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Current clinical management of smoke inhalation injuries: a reality check
Arietta Spinou, Nikolaos G. Koulouris

European Respiratory Journal 52 (6) 1802163; DOI: 10.1183/13993003.02163-2018 Published 6 December 2018
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The International Collaboration to Improve Respiratory Health in Children (INCIRCLE) ERS Clinical Research Collaboration
Peter D. Sly, Zoltán Hantos on behalf of the INCIRCLE Clinical Research Collaboration

European Respiratory Journal 52 (6) 1801867; DOI: 10.1183/13993003.01867-2018 Published 13 December 2018
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The European research collaboration for Children's Interstitial Lung Disease (ChILDEU) ERS Clinical Research Collaboration
Steve Cunningham, Carlee Gilbert, Nico Schwerk on behalf of the ChILDEU Clinical Research Collaboration Management Committee

European Respiratory Journal 52 (6) 1801855; DOI: 10.1183/13993003.01855-2018 Published 6 December 2018
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Inhaled corticosteroids in COPD: the final verdict is…
Janice M. Leung, Don D. Sin

European Respiratory Journal 52 (6) 1801940; DOI: 10.1183/13993003.01940-2018 Published 13 December 2018
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Triple therapy trials in COPD: a precision medicine opportunity
Samy Suissa, Amnon Ariel

European Respiratory Journal 52 (6) 1801848; DOI: 10.1183/13993003.01848-2018 Published 13 December 2018
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Letting the right one in: evaluating the generalisability of clinical trials
Rahul Shrimanker, Richard Beasley, Ciléin Kearns

European Respiratory Journal 52 (6) 1802218; DOI: 10.1183/13993003.02218-2018 Published 13 December 2018
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Dropping acid: why is cystic fibrosis mucus abnormal?
Bruce K. Rubin, David J. Thornton

European Respiratory Journal 52 (6) 1802057; DOI: 10.1183/13993003.02057-2018 Published 6 December 2018
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Targeting interleukin-13 in idiopathic pulmonary fibrosis: from promising path to dead end
Marlies S. Wijsenbeek, Mirjam Kool, Vincent Cottin

European Respiratory Journal 52 (6) 1802111; DOI: 10.1183/13993003.02111-2018 Published 13 December 2018
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Palliative care for patients with pulmonary fibrosis: symptom relief is essential
Kathleen Lindell, Ganesh Raghu

European Respiratory Journal 52 (6) 1802086; DOI: 10.1183/13993003.02086-2018 Published 6 December 2018
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New short regimens for latent tuberculosis treatment: safety first!
Dick Menzies, Anete Trajman

European Respiratory Journal 52 (6) 1802180; DOI: 10.1183/13993003.02180-2018 Published 20 December 2018

ERS Official Documents

ERS statement
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  ERS statement on harmonised standards for lung cancer registration and lung cancer services in Europe
  Anna L. Rich, David R. Baldwin, Paul Beckett, Thierry Berghmans, Jeanette Boyd, Corinne Faivre-Finn, Françoise Galateau-Salle, Fernando Gamarra, Bogdan Grigoriu, Niels-Christian G. Hansen, Georgia Hardavella, Erik Jakobsen, Dragana Jovanovic, Assia Konsoulova, Gilbert Massard, John McPhelim, Anne-Pascale Meert, Robert Milroy, Luciano Mutti, Marianne Paesmans, Michael D. Peake, Paul Martin Putora, Dirk K.M. de Ruysscher, Jean-Paul Sculier, Arnaud Scherpereel, Dragan R. Subotic, Paul Van Schil, Torsten Gerriet Blum
  
  European Respiratory Journal 52 (6) 1800610; DOI: 10.1183/13993003.00610-2018 Published 20 December 2018

Original Articles

Lung cancer
- Open Access
  Systematic evaluation of the efficacy–effectiveness gap of systemic treatments in metastatic nonsmall cell lung cancer
  Christine M. Cramer-van der Welle, Bas J.M. Peters, Franz M.N.H. Schramel, Olaf H. Klungel, Harry J.M. Groen, Ewoudt M.W. van de Garde for the Santeon NSCLC Study Group
  
  European Respiratory Journal 52 (6) 1801100; DOI: 10.1183/13993003.01100-2018 Published 20 December 2018
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  Variable radiological lung nodule evaluation leads to divergent management recommendations
  Arjun Nair, Emily C. Bartlett, Simon L.F. Walsh, Athol U. Wells, Neal Navani, Georgia Hardavella, Sanjeev Bhalla, Lucio Calandriello, Anand Devaraj, Jin Mo Goo, Jeffrey S. Klein, Heber MacMahon, C.M. Schaefer-Prokop, Joon-Beom Seo, Nicola Sverzellati, Sujal R. Desai and the Lung Nodule Evaluation Group
  
  European Respiratory Journal 52 (6) 1801359; DOI: 10.1183/13993003.01359-2018 Published 20 December 2018
Asthma
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  Randomised controlled trials in severe asthma: selection by phenotype or stereotype
  Thomas Brown, Thomas Jones, Kerry Gove, Clair Barber, Scott Elliott, Anoop Chauhan, Peter Howarth on behalf of the Wessex Severe Asthma Cohort (WSAC) team
  
  European Respiratory Journal 52 (6) 1801444; DOI: 10.1183/13993003.01444-2018 Published 13 December 2018
Cystic fibrosis
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  Pathological mucus and impaired mucus clearance in cystic fibrosis patients result from increased concentration, not altered pH
  David B. Hill, Robert F. Long, William J. Kissner, Eyad Atieh, Ian C. Garbarine, Matthew R. Markovetz, Nicholas C. Fontana, Matthew Christy, Mehdi Habibpour, Robert Tarran, M. Gregory Forest, Richard C. Boucher, Brian Button
  
  European Respiratory Journal 52 (6) 1801297; DOI: 10.1183/13993003.01297-2018 Published 6 December 2018
Interstitial lung diseases
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  SAR156597 in idiopathic pulmonary fibrosis: a phase 2 placebo-controlled study (DRI11772)
  Ganesh Raghu, Luca Richeldi, Bruno Crestani, Peter Wung, Raphael Bejuit, Corinne Esperet, Christian Antoni, Christina Soubrane
  
  European Respiratory Journal 52 (6) 1801130; DOI: 10.1183/13993003.01130-2018 Published 13 December 2018
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  Safety of benzodiazepines and opioids in interstitial lung disease: a national prospective study
  Sabrina Bajwah, Joanna M. Davies, Hanan Tanash, David C. Currow, Adejoke O. Oluyase, Magnus Ekström
  
  European Respiratory Journal 52 (6) 1801278; DOI: 10.1183/13993003.01278-2018 Published 6 December 2018
Tuberculosis
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  Short-course regimens of rifapentine plus isoniazid to treat latent tuberculosis infection in older Chinese patients: a randomised controlled study
  Lei Gao, Haoran Zhang, Henan Xin, Jianmin Liu, Shouguo Pan, Xiangwei Li, Ling Guan, Fei Shen, Zisen Liu, Dakuan Wang, Xueling Guan, Jiaoxia Yan, Hengjing Li, Boxuan Feng, Xuefang Cao, Yu Chen, Wei Cui, Zongde Zhang, Yu Ma, Xiaoyou Chen, Xinhua Zhou, Qi Jin for the LATENTTB-NSTM study team
  
  European Respiratory Journal 52 (6) 1801470; DOI: 10.1183/13993003.01470-2018 Published 20 December 2018
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  Estimating the prevalence of latent tuberculosis in a low-incidence setting: Australia
  Katie Dorothy Dale, James McCracken Trauer, Pete J. Dodd, Rein M.G.J. Houben, Justin Timothy Denholm
  
  European Respiratory Journal 52 (6) 1801218; DOI: 10.1183/13993003.01218-2018 Published 20 December 2018
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  High treatment success rate for multidrug-resistant and extensively drug-resistant tuberculosis using a bedaquiline-containing treatment regimen
  Norbert Ndjeka, Kathryn Schnippel, Iqbal Master, Graeme Meintjes, Gary Maartens, Rodolfo Romero, Xavier Padanilam, Martin Enwerem, Sunitha Chotoo, Nalini Singh, Jennifer Hughes, Ebrahim Variava, Hannetjie Ferreira, Julian te Riele, Nazir Ismail, Erika Mohr, Nonkqubela Bantubani, Francesca Conradie
  
  European Respiratory Journal 52 (6) 1801528; DOI: 10.1183/13993003.01528-2018 Published 20 December 2018
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  Tuberculosis in the European Union and European Economic Area: a survey of national tuberculosis programmes
  Simon M. Collin, Gerard de Vries, Knut Lönnroth, Giovanni Battista Migliori, Ibrahim Abubakar, Sarah R. Anderson, Dominik Zenner
  
  European Respiratory Journal 52 (6) 1801449; DOI: 10.1183/13993003.01449-2018 Published 6 December 2018
Allergy and basic science
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  Innate lymphoid cells in the upper airways: importance of CD117 and IL-1RI expression
  Koen Van Crombruggen, Sylvie Taveirne, Gabriele Holtappels, Georges Leclercq, Claus Bachert
  
  European Respiratory Journal 52 (6) 1800742; DOI: 10.1183/13993003.00742-2018 Published 6 December 2018

Reviews

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Triple therapy versus single and dual long-acting bronchodilator therapy in COPD: a systematic review and meta-analysis
Mario Cazzola, Paola Rogliani, Luigino Calzetta, Maria Gabriella Matera

European Respiratory Journal 52 (6) 1801586; DOI: 10.1183/13993003.01586-2018 Published 13 December 2018
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Inhaled corticosteroids in COPD: friend or foe?
Alvar Agusti, Leonardo M. Fabbri, Dave Singh, Jørgen Vestbo, Bartolome Celli, Frits M.E. Franssen, Klaus F. Rabe, Alberto Papi

European Respiratory Journal 52 (6) 1801219; DOI: 10.1183/13993003.01219-2018 Published 13 December 2018

Series

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What is early COPD and why is it important?
Joan B. Soriano, Francesca Polverino, Borja G. Cosio

European Respiratory Journal 52 (6) 1801448; DOI: 10.1183/13993003.01448-2018 Published 6 December 2018

Agora

Research letters
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  The cystic fibrosis airway milieu enhances rescue of F508del in a pre-clinical model
  Martina Gentzsch, Deborah M. Cholon, Nancy L. Quinney, Susan E. Boyles, Mary E.B. Martino, Carla M.P. Ribeiro
  
  European Respiratory Journal 52 (6) 1801133; DOI: 10.1183/13993003.01133-2018 Published 20 December 2018
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  Dramatic response of refractory sarcoidosis under ruxolitinib in a patient with associated JAK2-mutated polycythemia
  Cécile Rotenberg, Valérie Besnard, Pierre-Yves Brillet, Stéphane Giraudier, Hilario Nunes, Dominique Valeyre
  
  European Respiratory Journal 52 (6) 1801482; DOI: 10.1183/13993003.01482-2018 Published 20 December 2018
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  Inhaled corticosteroid containing combinations and mortality in COPD
  Jørgen Vestbo, Leonardo Fabbri, Alberto Papi, Stefano Petruzzelli, Mario Scuri, Alessandro Guasconi, Stefano Vezzoli, Dave Singh
  
  European Respiratory Journal 52 (6) 1801230; DOI: 10.1183/13993003.01230-2018 Published 13 December 2018
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  Exacerbations of severe asthma in patients treated with mepolizumab
  Rahul Shrimanker, Ian D. Pavord, Steve Yancey, Liam G. Heaney, Ruth H. Green, Peter Bradding, Beverley Hargadon, Chris E. Brightling, Andrew J. Wardlaw, Pranabashis Haldar
  
  European Respiratory Journal 52 (6) 1801127; DOI: 10.1183/13993003.01127-2018 Published 13 December 2018
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  A systematic review of clinical trial registration in major respiratory journals 2010–2018
  Nelli S.M. Suntila, Alexandria Smith, Yusuf Al-Dabbagh, James D. Chalmers
  
  European Respiratory Journal 52 (6) 1801491; DOI: 10.1183/13993003.01491-2018 Published 6 December 2018
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  Determinants of diagnostic delay in chronic thromboembolic pulmonary hypertension: results from the European CTEPH Registry
  Frederikus A. Klok, Stefano Barco, Stavros V. Konstantinides, Philippe Dartevelle, Elie Fadel, David Jenkins, Nick H. Kim, Michael Madani, Hiromi Matsubara, Eckhard Mayer, Joanna Pepke-Zaba, Marion Delcroix, Irene M. Lang
  
  European Respiratory Journal 52 (6) 1801687; DOI: 10.1183/13993003.01687-2018 Published 6 December 2018
Correspondence
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  Challenges in interpreting trends in testing for α₁-antitrypsin deficiency in COPD patients from UK primary care
  Daniel R. Morales
  
  European Respiratory Journal 52 (6) 1801986; DOI: 10.1183/13993003.01986-2018 Published 20 December 2018
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  Challenges in interpreting trends in testing for α₁-antitrypsin deficiency in COPD patients from UK primary care
  Joan B. Soriano on behalf of all co-authors
  
  European Respiratory Journal 52 (6) 1802064; DOI: 10.1183/13993003.02064-2018 Published 20 December 2018
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  Improving the management of spontaneous pneumothorax
  Uri Kartoun
  
  European Respiratory Journal 52 (6) 1801857; DOI: 10.1183/13993003.01857-2018 Published 6 December 2018
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  Improving the management of spontaneous pneumothorax
  José M. Porcel
  
  European Respiratory Journal 52 (6) 1801918; DOI: 10.1183/13993003.01918-2018 Published 6 December 2018

Author Correction

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“Physical activity as a moderator for obstructive sleep apnoea and cardiometabolic risk in the EPISONO study.” Marcos Mônico-Neto, Hanna Karen Moreira Antunes, Ronaldo Vagner Thomatieli dos Santos, Vânia D'Almeida, Altay Alves Lino de Souza, Lia Rita Azeredo Bittencourt and Sergio Tufik. Eur Respir J 2018; 52: 1701972.
European Respiratory Journal 52 (6) 1751972; DOI: 10.1183/13993003.51972-2017 Published 13 December 2018

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Table of Contents

Editorials

ERS Official Documents

ERS statement

Original Articles

Lung cancer

Asthma

Cystic fibrosis

Interstitial lung diseases

Tuberculosis

Allergy and basic science

Reviews

Series

Agora

Research letters

Correspondence

Author Correction

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