Patients | 132 | 24 | 72 | 23 | 13 | |
Underlying disease | | | | | | |
IPF | 78 (59%) | 14 (58%) | 31 (43%) | 23 (100%) | 10 (77%) | 0.001 |
Unspecified fibrosis | 22 (17%) | 6 (25%) | 15 (21%) | 0 (0%) | 1 (8%) | 0.059 |
Fibroelastosis | 1 (1%) | 1 (4%) | 0 (0%) | 0 (0%) | 0 (0%) | 0.209 |
NSIP | 8 (6%) | 0 (0%) | 7 (10%) | 0 (0%) | 1 (8%) | 0.188 |
Organising pneumonia | 1 (1%) | 0 (0%) | 1 (1%) | 0 (0%) | 0 (0%) | 0.840 |
Hypersensitivity pneumonitis | 12 (9%) | 0 (0%) | 12 (17%) | 0 (0%) | 0 (0%) | 0.012 |
CPFE | 6 (5%) | 3 (13%) | 2 (3%) | 0 (0%) | 1 (8%) | 0.344 |
Silicosis | 1 (1%) | 0 (0%) | 1 (1%) | 0 (0%) | 0 (0%) | 0.840 |
Systemic sclerosis | 3 (2%) | 0 (0%) | 3 (4%) | 0 (0%) | 0 (0%) | 0.465 |
Baseline characteristics | | | | | | |
Age years | 57.0 (51.5–62.5) | 58.5 (54–63) | 56.0 (49–63) | 59.0 (55.5–62.5) | 58.0 (53.5–62.5) | 0.097 |
Males | 93 (70%) | 19 (79%) | 41 (57%) | 22 (96%) | 11 (85%) | 0.001 |
BMI kg·m−2 | 24.5±3.3 | 23.1±3.2 | 24.7±3.3 | 25.8±3.2 | 24.7±2.7 | 0.251 |
FVC % pred | 42 (31–53) | 46 (32–60) | 41 (30–51) | 45 (37–52) | 40 (27–53) | 0.675 |
TLC % pred | 58±13 | 63±16 | 56±12 | 55±11 | 59±13 | 0.507 |
LAS score | 38 (33–43) | 37 (33–40) | 39 (34–45) | 38 (26–50) | 37 (33–40) | 0.630 |
6-min walking distance m | 266±133 | 280±149 | 241±129 | 330±121 | 310±122 | 0.086 |
Peri- and post-operative specifics | | | | | | |
Surgery duration min | 300±68 | 286±83 | 300±65 | 306±58 | 318±70 | 0.661 |
ECMO support | 74 (56%) | 18 (75%) | 39 (54%) | 11 (48%) | 6 (46%) | 0.191 |
Packed red blood cell units | 2.0 (0–4.0) | 2.0 (0–4.0) | 2.0 (0–4.0) | 2.0 (0–5.0) | 1.5 (0–3.0) | 0.828 |
Intubation duration days | 1.0 (0.5–1.5) | 2.0 (1.5–2.5) | 1.0 (0.5–1.5) | 1.0 (0.5–1.5) | 1.0 (0.5–1.5) | 0.629 |
Hb pre-LuTx g·dL−1 | 14.2±2 | 14.3±2 | 14.0±2 | 14.1±2 | 15.0±2 | 0.391 |
Hb D1 g·dL−1 | 11.2±1 | 11.2±1 | 11.2±1 | 11.0±2 | 11.7±1 | 0.643 |
Haemothorax surgery# | 11 (8%) | 1 (4%) | 7 (10%) | 3 (13%) | 0 (0%) | 0.595 |
Wound infection with VAC therapy | 12 (9%) | 2 (8%) | 7 (10%) | 3 (13%) | 0 (0%) | 0.763 |
GI bleeding | 3 (2%) | 1 (4%) | 1 (1%) | 1 (4%) | 0 (0%) | 0.520 |
Renal failure | 13 (10%) | 1 (4%) | 9 (13%) | 2 (9%) | 1 (8%) | 0.815 |
Anastomosis problems (total anastomoses) | 1 (264) | 0 (48) | 1 (144) | 0 (46) | 0 (26) | 0.841 |