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Table of Contents

01 June 2018; volume 51, issue 6

Editorials

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    A harmonised European training syllabus for thoracic surgery: report from the ESTS/ERS task force group
    Gilbert Massard, Nathalie Tabin, Sharon Mitchell, Hasan Batirel, Alessandro Brunelli, Stefano Elia, Anna Frick, Martin Huertgen, Antoon Lerut, Laureano Molins, Kostas Papagiannopoulos, Dragan Subotic, Paul van Schil, Gonzalo Varela, Dirk van Raemdonck
    European Respiratory Journal 51 (6) 1800370; DOI: 10.1183/13993003.00370-2018 Published 14 June 2018
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    Beyond oestrogens: towards a broader evaluation of the hormone profile in pulmonary arterial hypertension
    Jessica B. Badlam, Eric D. Austin
    European Respiratory Journal 51 (6) 1801058; DOI: 10.1183/13993003.01058-2018 Published 28 June 2018
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    ACE2 as therapy for pulmonary arterial hypertension: the good outweighs the bad
    Christophe Guignabert, Frances de Man, Marc Lombès
    European Respiratory Journal 51 (6) 1800848; DOI: 10.1183/13993003.00848-2018 Published 21 June 2018
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    Gastro-oesophageal reflux and idiopathic pulmonary fibrosis: the heart burn in patients with IPF can no longer be silent
    Michael Kreuter, Ganesh Raghu
    European Respiratory Journal 51 (6) 1800921; DOI: 10.1183/13993003.00921-2018 Published 21 June 2018
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    Mortality in interstitial lung disease: do race and skin colour matter?
    Julie Morisset, Yolanda Mageto, Ganesh Raghu
    European Respiratory Journal 51 (6) 1800892; DOI: 10.1183/13993003.00892-2018 Published 14 June 2018
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    The ageing brain in sleep apnoea: paradoxical resilience, survival of the fittest, or simply comparing apples and oranges?
    David Gozal
    European Respiratory Journal 51 (6) 1800802; DOI: 10.1183/13993003.00802-2018 Published 14 June 2018
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    Is low level of vitamin D a marker of poor health, or a cause?
    Om P. Kurmi
    European Respiratory Journal 51 (6) 1800931; DOI: 10.1183/13993003.00931-2018 Published 7 June 2018
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    NO way! Nasal nitric oxide measurement in infants
    Jane S. Lucas, Woolf T. Walker
    European Respiratory Journal 51 (6) 1800958; DOI: 10.1183/13993003.00958-2018 Published 21 June 2018
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    Obstructive sleep apnoea and exercise functional capacity: time to move?
    Núria Farré, Geraldo Lorenzi-Filho
    European Respiratory Journal 51 (6) 1801031; DOI: 10.1183/13993003.01031-2018 Published 28 June 2018

Original articles

  • Pulmonary vascular diseases

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      Lower DHEA-S levels predict disease and worse outcomes in post-menopausal women with idiopathic, connective tissue disease- and congenital heart disease-associated pulmonary arterial hypertension
      Grayson L. Baird, Christine Archer-Chicko, R. Graham Barr, David A. Bluemke, Andrew E. Foderaro, Jason S. Fritz, Nicholas S. Hill, Steven M. Kawut, James R. Klinger, Joao A.C. Lima, Christopher J. Mullin, Pamela Ouyang, Harold I. Palevsky, Amy J. Palmisicano, Diane Pinder, Ioana R. Preston, Kari E. Roberts, K. Akaya Smith, Thomas Walsh, Mary Whittenhall, Corey E. Ventetuolo
      European Respiratory Journal 51 (6) 1800467; DOI: 10.1183/13993003.00467-2018 Published 28 June 2018
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      A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension
      Anna R. Hemnes, Anandharajan Rathinasabapathy, Eric A. Austin, Evan L. Brittain, Erica J. Carrier, Xinping Chen, Joshua P. Fessel, Candice D. Fike, Peter Fong, Niki Fortune, Robert E. Gerszten, Jennifer A. Johnson, Mark Kaplowitz, John H. Newman, Robert Piana, Meredith E. Pugh, Todd W. Rice, Ivan M. Robbins, Lisa Wheeler, Chang Yu, James E. Loyd, James West
      European Respiratory Journal 51 (6) 1702638; DOI: 10.1183/13993003.02638-2017 Published 21 June 2018
  • Tuberculosis

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      The use of whole-genome sequencing in cluster investigation of a multidrug-resistant tuberculosis outbreak
      Maeve K. Lalor, Nicola Casali, Timothy M. Walker, Laura F. Anderson, Jennifer A. Davidson, Natasha Ratna, Cathy Mullarkey, Mike Gent, Kirsty Foster, Tim Brown, John Magee, Anne Barrett, Derrick W. Crook, Francis Drobniewski, H. Lucy Thomas, Ibrahim Abubakar
      European Respiratory Journal 51 (6) 1702313; DOI: 10.1183/13993003.02313-2017 Published 21 June 2018
    • Open Access
      Delamanid for rifampicin-resistant tuberculosis: a retrospective study from South Africa
      Erika Mohr, Jennifer Hughes, Anja Reuter, Laura Trivino Duran, Gabriella Ferlazzo, Johnny Daniels, Virginia De Azevedo, Yulene Kock, Sarah Jane Steele, Amir Shroufi, Serge Ade, Natavan Alikhanova, Guido Benedetti, Jeffrey Edwards, Helen Cox, Jennifer Furin, Petros Isaakidis
      European Respiratory Journal 51 (6) 1800017; DOI: 10.1183/13993003.00017-2018 Published 14 June 2018
  • Interstitial lung diseases

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      The effect of anti-acid therapy on survival in idiopathic pulmonary fibrosis: a methodological review of observational studies
      Tanja Tran, Samy Suissa
      European Respiratory Journal 51 (6) 1800376; DOI: 10.1183/13993003.00376-2018 Published 21 June 2018
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      African-American race and mortality in interstitial lung disease: a multicentre propensity-matched analysis
      Ayodeji Adegunsoye, Justin M. Oldham, Shashi K. Bellam, Jonathan H. Chung, Paul A. Chung, Kathleen M. Biblowitz, Steven Montner, Cathryn Lee, Scully Hsu, Aliya N. Husain, Rekha Vij, Gokhan Mutlu, Imre Noth, Matthew M. Churpek, Mary E. Strek
      European Respiratory Journal 51 (6) 1800255; DOI: 10.1183/13993003.00255-2018 Published 14 June 2018
  • Sleep

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      Increased liver stiffness in patients with severe sleep apnoea and metabolic comorbidities
      Wojciech Trzepizur, Jérôme Boursier, Marc Le Vaillant, Pierre-Henri Ducluzeau, Séverine Dubois, Samir Henni, Pierre Abraham, Christophe Aubé, Paul Calès, Frédéric Gagnadoux on the behalf of the METABOL group
      European Respiratory Journal 51 (6) 1800601; DOI: 10.1183/13993003.00601-2018 Published 28 June 2018
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      Sleep apnoea in the asymptomatic elderly: a real issue for the brain?
      Sébastien Celle, Claire Boutet, Cédric Annweiler, Jean-Claude Barthélémy, Frédéric Roche
      European Respiratory Journal 51 (6) 1702450; DOI: 10.1183/13993003.02450-2017 Published 14 June 2018
  • Cancer

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      Serum 25-hydroxyvitamin D levels and risk of lung cancer and histologic types: a Mendelian randomisation analysis of the HUNT study
      Yi-Qian Sun, Ben M. Brumpton, Carolina Bonilla, Sarah J. Lewis, Stephen Burgess, Frank Skorpen, Yue Chen, Tom I.L. Nilsen, Pål Richard Romundstad, Xiao-Mei Mai
      European Respiratory Journal 51 (6) 1800329; DOI: 10.1183/13993003.00329-2018 Published 7 June 2018
  • Paediatrics

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      Infant nasal nitric oxide over time: natural evolution and impact of respiratory tract infection
      June K. Marthin, Maria C. Philipsen, Susanne Rosthoj, Kim G. Nielsen
      European Respiratory Journal 51 (6) 1702503; DOI: 10.1183/13993003.02503-2017 Published 21 June 2018
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      Risk factors for lung disease progression in children with cystic fibrosis
      Marieke van Horck, Kim van de Kant, Bjorn Winkens, Geertjan Wesseling, Vincent Gulmans, Han Hendriks, Chris van der Grinten, Quirijn Jöbsis, Edward Dompeling
      European Respiratory Journal 51 (6) 1702509; DOI: 10.1183/13993003.02509-2017 Published 7 June 2018
    • Open Access
      Tobacco smoke exposure in early life and adolescence in relation to lung function
      Jesse D. Thacher, Erica S. Schultz, Jenny Hallberg, Ulrika Hellberg, Inger Kull, Per Thunqvist, Göran Pershagen, Per M. Gustafsson, Erik Melén, Anna Bergström
      European Respiratory Journal 51 (6) 1702111; DOI: 10.1183/13993003.02111-2017 Published 7 June 2018
  • Asthma

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      Understanding patients' perceptions of asthma control: a qualitative study
      Natalie Bidad, Neil Barnes, Chris Griffiths, Rob Horne
      European Respiratory Journal 51 (6) 1701346; DOI: 10.1183/13993003.01346-2017 Published 28 June 2018
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      Do laboratory challenge tests for occupational asthma represent what happens in the workplace?
      P. Sherwood Burge, Vicky C. Moore, Alastair S. Robertson, Gareth I. Walters
      European Respiratory Journal 51 (6) 1800059; DOI: 10.1183/13993003.00059-2018 Published 28 June 2018
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      Maternal age at delivery, lung function and asthma in offspring: a population-based survey
      Francisco Gómez Real, John A. Burgess, Simona Villani, Julia Dratva, Joachim Heinrich, Christer Janson, Debbie Jarvis, Jennifer Koplin, Bénédicte Leynaert, Caroline Lodge, Birger N. Lærum, Melanie C. Matheson, Dan Norbäck, Ernst R. Omenaas, Svein M. Skulstad, Jordi Sunyer, Shyamali C. Dharmage, Cecilie Svanes
      European Respiratory Journal 51 (6) 1601611; DOI: 10.1183/13993003.01611-2016 Published 7 June 2018

Review

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    Maximal exercise capacity in patients with obstructive sleep apnoea syndrome: a systematic review and meta-analysis
    Monique Mendelson, Mathieu Marillier, Sébastien Bailly, Patrice Flore, Jean-Christian Borel, Isabelle Vivodtzev, Stéphane Doutreleau, Renaud Tamisier, Jean-Louis Pépin, Samuel Verges
    European Respiratory Journal 51 (6) 1702697; DOI: 10.1183/13993003.02697-2017 Published 28 June 2018

Agora

  • Research letters

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      What is the minimal clinically important difference for helium-3 magnetic resonance imaging ventilation defects?
      Rachel L. Eddy, Sarah Svenningsen, David G. McCormack, Grace Parraga
      European Respiratory Journal 51 (6) 1800324; DOI: 10.1183/13993003.00324-2018 Published 28 June 2018
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      Countrywide implementation of whole genome sequencing: an opportunity to improve tuberculosis management, surveillance and contact tracing in low incidence countries
      Andrea Maurizio Cabibbe, Alberto Trovato, Maria Rosaria De Filippo, Arash Ghodousi, Laura Rindi, Carlo Garzelli, Simonetta Baretti, Guendalina Allodi, Roberta Mannino, Gian Maria Rossolini, Alessandro Bartoloni, Enrico Tortoli, Daniela Maria Cirillo
      European Respiratory Journal 51 (6) 1800387; DOI: 10.1183/13993003.00387-2018 Published 28 June 2018
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      Pulmonary haemodynamics and mortality in chronic hypersensitivity pneumonitis
      Rudolf K.F. Oliveira, Jaquelina S. Ota-Arakaki, Paula S. Gomes, Andrea Gimenez, Carolina M.S. Messina, Roberta P. Ramos, Eloara V.M. Ferreira, David M. Systrom, Carlos A.C. Pereira
      European Respiratory Journal 51 (6) 1800430; DOI: 10.1183/13993003.00430-2018 Published 21 June 2018
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      Effect of antifibrotics on short-term outcome after bilateral lung transplantation: a multicentre analysis
      Christopher Lambers, Panja M. Boehm, Silvia Lee, Fabio Ius, Peter Jaksch, Walter Klepetko, Igor Tudorache, Robin Ristl, Tobias Welte, Jens Gottlieb
      European Respiratory Journal 51 (6) 1800503; DOI: 10.1183/13993003.00503-2018 Published 21 June 2018
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      Early experience with delamanid-containing regimens in the treatment of complicated multidrug-resistant tuberculosis in Hong Kong
      Kwok-Chiu Chang, Eric Chung-Ching Leung, Wing-Sze Law, Wai-Man Leung, Lai-Bun Tai, Shuk-Nor Lee, Fai-Man Lam, Chi-Hung Chau, Thomas Yun-Wing Mok, Wing-Wai Yew, Chi-Chiu Leung
      European Respiratory Journal 51 (6) 1800159; DOI: 10.1183/13993003.00159-2018 Published 14 June 2018
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      Survival of patients with schistosomiasis-associated pulmonary arterial hypertension in the modern management era
      Caio Julio Cesar Fernandes, Bruna Piloto, Marcela Castro, Francisca Gavilanes Oleas, Jose Leonidas Alves Jr, Luis Felipe Lopes Prada, Carlos Jardim, Rogerio Souza
      European Respiratory Journal 51 (6) 1800307; DOI: 10.1183/13993003.00307-2018 Published 14 June 2018
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      Personalised CFTR pharmacotherapeutic response testing and therapy of cystic fibrosis
      Cormac McCarthy, John J. Brewington, Beth Harkness, John P. Clancy, Bruce C. Trapnell
      European Respiratory Journal 51 (6) 1702457; DOI: 10.1183/13993003.02457-2017 Published 7 June 2018
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      Nasopharyngeal aspirate value in paediatric chronic lower respiratory tract illness
      Francesca Lunardi, Stefania Edith Vuljan, Egle Perissinotto, Federica Pezzuto, Sandro Malacrida, Samuela Bugin, Ilaria Bertozzi, Deborah Snijders, Stefania Rizzo, Angelo Barbato, Fiorella Calabrese
      European Respiratory Journal 51 (6) 1701783; DOI: 10.1183/13993003.01783-2017 Published 7 June 2018
  • Correspondence

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      Cost-effectiveness of biomarker testing for treatment choices in advanced non-small cell lung carcinoma: impact of diagnostic strategies and their turnaround times
      Arnaud Uguen
      European Respiratory Journal 51 (6) 1800602; DOI: 10.1183/13993003.00602-2018 Published 21 June 2018
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      Cost-effectiveness of biomarker testing for treatment choices in advanced non-small cell lung carcinoma: impact of diagnostic strategies and their turnaround times
      Sandrine Loubière, Fabrice Barlesi, Pascale Missy, Franck Morin, Pascal Auquier, Jacques Cadranel
      European Respiratory Journal 51 (6) 1800844; DOI: 10.1183/13993003.00844-2018 Published 21 June 2018
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      A multi-organ loss of tissue phenotype in COPD: involvement of the functional muscle–bone unit
      Toshihiro Sugiyama
      European Respiratory Journal 51 (6) 1800657; DOI: 10.1183/13993003.00657-2018 Published 14 June 2018
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      The association of cardiovascular autonomic dysfunction and the prediction of COPD can be explained by neurohumoral activation
      Stefan Andreas
      European Respiratory Journal 51 (6) 1800737; DOI: 10.1183/13993003.00737-2018 Published 7 June 2018
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      Dysregulation of the “inflammatory reflex” with abnormal neurohumoral activation may contribute to proinflammatory activity driving the progression of COPD
      Fabrizio Ricci, Per Wollmer, Gunnar Engström, Artur Fedorowski, Viktor Hamrefors
      European Respiratory Journal 51 (6) 1800806; DOI: 10.1183/13993003.00806-2018 Published 7 June 2018

Author Correction

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    “Number needed to treat: enigmatic results for exacerbations in COPD.” Samy Suissa. Eur Respir J 2015; 45: 875–878.
    European Respiratory Journal 51 (6) 1452165; DOI: 10.1183/13993003.52165-2014 Published 14 June 2018
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European Respiratory Journal: 51 (6)
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