Tables
- TABLE 1
Free serum and tissue linezolid concentrations and lung to serum drug concentration ratios among patients with drug-resistant pulmonary tuberculosis
Patient Dose mg·kg−1 Free serum concentration at time of resection# µg·mL−1 Non-diseased lung tissue concentration µg·mL−1 Diseased lung tissue concentration µg·mL−1 Diseased lung/serum Non-diseased lung/serum 1 9.23 7.73 10.24 7.09 0.92 1.32 2 11.54 10.06 4.27 6.60 0.66 0.42 3 8.33 8.79 3.43 4.27 0.49 0.42 4 7.50 7.24 2.03 1.30 0.17 0.27 5 7.69 7.71 6.01 4.22 0.55 0.78 6 6.19 3.68 1.17 0.81 0.22 0.32 7 8.33 5.87 1.25 2.91 0.50 0.21 8 10.53 10.54 4.97 2.75 0.26 0.47 Median 8.33 7.77 3.85 3.56 0.49 0.41 #: free serum concentration=measured linezolid concentration×0.69.
Supplementary Materials
Supplementary Material
H.M. Blumberg ERJ-02166-2017_Blumberg
R.R. Kempker ERJ-02166-2017_Kempker
C.A. Peloquin ERJ-02166-2017_Peloquin
Vol 51 Issue 2
Table of Contents
A comparison of linezolid lung tissue concentrations among patients with drug-resistant tuberculosis
