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RV568, a narrow-spectrum kinase inhibitor with p38 MAPK-α and -γ selectivity, suppresses COPD inflammation

Catherine E. Charron, Paul Russell, Kazuhiro Ito, Simon Lea, Yasuo Kizawa, Charlie Brindley, Dave Singh
European Respiratory Journal 2017 50: 1700188; DOI: 10.1183/13993003.00188-2017
Catherine E. Charron
1RespiVert Ltd, London Bioscience Innovation Centre, London, UK
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  • For correspondence: mcecharron@gmail.com
Paul Russell
1RespiVert Ltd, London Bioscience Innovation Centre, London, UK
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  • ORCID record for Paul Russell
Kazuhiro Ito
1RespiVert Ltd, London Bioscience Innovation Centre, London, UK
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Simon Lea
2Medicines Evaluation Unit, Centre for Respiratory Medicine and Allergy, University of Manchester, University Hospital of South Manchester, Manchester, UK
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Yasuo Kizawa
3Dept of Physiology and Anatomy, Nihon University School of Pharmacy, Funabashi, Japan
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Charlie Brindley
4KinetAssist Limited, Quothquan, UK
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Dave Singh
2Medicines Evaluation Unit, Centre for Respiratory Medicine and Allergy, University of Manchester, University Hospital of South Manchester, Manchester, UK
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Article Information

vol. 50 no. 4
DOI 
https://doi.org/10.1183/13993003.00188-2017
PubMed 
29074542

Published By 
European Respiratory Society
Print ISSN 
0903-1936
Online ISSN 
1399-3003
History 
  • Received January 26, 2017
  • Accepted July 27, 2017
  • Published online October 26, 2017.

Copyright & Usage 
Copyright ©ERS 2017

Author Information

  1. Catherine E. Charron1⇑,
  2. Paul Russell1,
  3. Kazuhiro Ito1,
  4. Simon Lea2,
  5. Yasuo Kizawa3,
  6. Charlie Brindley4 and
  7. Dave Singh2
  1. 1RespiVert Ltd, London Bioscience Innovation Centre, London, UK
  2. 2Medicines Evaluation Unit, Centre for Respiratory Medicine and Allergy, University of Manchester, University Hospital of South Manchester, Manchester, UK
  3. 3Dept of Physiology and Anatomy, Nihon University School of Pharmacy, Funabashi, Japan
  4. 4KinetAssist Limited, Quothquan, UK
  1. Catherine E. Charron, RespiVert Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London, NW1 0NH, UK. E-mail: mcecharron{at}gmail.com
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Funding

  • National Institute for Health Research

    South Manchester Respiratory and Allergy Clinical

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Vol 50 Issue 4 Table of Contents
European Respiratory Journal: 50 (4)
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RV568, a narrow-spectrum kinase inhibitor with p38 MAPK-α and -γ selectivity, suppresses COPD inflammation
Catherine E. Charron, Paul Russell, Kazuhiro Ito, Simon Lea, Yasuo Kizawa, Charlie Brindley, Dave Singh
European Respiratory Journal Oct 2017, 50 (4) 1700188; DOI: 10.1183/13993003.00188-2017

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RV568, a narrow-spectrum kinase inhibitor with p38 MAPK-α and -γ selectivity, suppresses COPD inflammation
Catherine E. Charron, Paul Russell, Kazuhiro Ito, Simon Lea, Yasuo Kizawa, Charlie Brindley, Dave Singh
European Respiratory Journal Oct 2017, 50 (4) 1700188; DOI: 10.1183/13993003.00188-2017
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  • Article
    • Abstract
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  • COPD and smoking
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