Tables
- TABLE 1
Interpretation of strong and conditional recommendations for stakeholders (patients, clinicians and healthcare policy makers)
Strong recommendation Weak recommendation For patients Most individuals in this situation would want the recommended course of action and only a small proportion would not. The majority of individuals in this situation would want the suggested course of action, but many would not. For clinicians Most individuals should receive the recommended course of action. Adherence to this recommendation according to the guideline could be used as a quality criterion or performance indicator. Formal decision aids are not likely to be needed to help individuals make decisions consistent with their values and preferences. Different choices are likely to be appropriate for different patients and therapy should be tailored to the individual patient's circumstances. Those circumstances may include the patient or family's values and preferences. For policy makers The recommendation can be adapted as policy in most situations including for the use as performance indicators. Policy making will require substantial debates and involvement of many stakeholders. Policies are also more likely to vary between regions. Performance indicators would have to focus on the fact that adequate deliberation about the management options has taken place. - TABLE 2
Recommendations for actionable PICO questions
Clinical indication# Certainty of evidence¶ Recommendation Prevention of hypercapnia in COPD exacerbation ⊕⊕ Conditional recommendation against Hypercapnia with COPD exacerbation ⊕⊕⊕⊕ Strong recommendation for Cardiogenic pulmonary oedema ⊕⊕⊕ Strong recommendation for Acute asthma exacerbation No recommendation made Immunocompromised ⊕⊕⊕ Conditional recommendation for De novo respiratory failure No recommendation made Post-operative patients ⊕⊕⊕ Conditional recommendation for Palliative care ⊕⊕⊕ Conditional recommendation for Trauma ⊕⊕⊕ Conditional recommendation for Pandemic viral illness No recommendation made Post-extubation in high-risk patients (prophylaxis) ⊕⊕ Conditional recommendation for Post-extubation respiratory failure ⊕⊕ Conditional recommendation against Weaning in hypercapnic patients ⊕⊕⊕ Conditional recommendation for #: all in the setting of acute respiratory failure; ¶: certainty of effect estimates: ⊕⊕⊕⊕, high; ⊕⊕⊕, moderate; ⊕⊕, low; ⊕, very low.
Supplementary Materials
Supplementary Material
Please note: supplementary material is not edited by the Editorial Office, and is uploaded as it has been supplied by the author.
Technical summary: Practical application of noninvasive ventilation in the hospital setting ERJ-02426-2016_Technical_summary
Supplementary material: extended methods section ERJ-02426-2016_Extended_methods
Supplementary material: evidence profiles and forest plots ERJ-02426-2016_Evidence_profiles
Supplementary Material
M. Antonelli ERJ-02426-2016_Antonelli
L. Brochard ERJ-02426-2016_Brochard
M.W. Elliott ERJ-02426-2016_Elliott
K. Guntupalli ERJ-02426-2016_Guntupalli
D. Hess ERJ-02426-2016_Hess
N. Hill ERJ-02426-2016_Hill
S. Jaber ERJ-02426-2016_Jaber
J. Mancebo ERJ-02426-2016_Mancebo
S. Nava ERJ-02426-2016_Nava
P. Navalesi ERJ-02426-2016_Navalesi
