Table of Contents

Original articles

• Pulmonary vascular diseases

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    Oestrogen inhibition reverses pulmonary arterial hypertension and associated metabolic defects

    Xinping Chen, Eric D. Austin, Megha Talati, Joshua P. Fessel, Eric H. Farber-Eger, Evan L. Brittain, Anna R. Hemnes, James E. Loyd, James West

    European Respiratory Journal 50 (2) 1602337; DOI: 10.1183/13993003.02337-2016 Published 3 August 2017
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    Mortality in pulmonary arterial hypertension: prediction by the 2015 European pulmonary hypertension guidelines risk stratification model

    Marius M. Hoeper, Tilmann Kramer, Zixuan Pan, Christina A. Eichstaedt, Jens Spiesshoefer, Nicola Benjamin, Karen M. Olsson, Katrin Meyer, Carmine Dario Vizza, Anton Vonk-Noordegraaf, Oliver Distler, Christian Opitz, J. Simon R. Gibbs, Marion Delcroix, H. Ardeschir Ghofrani, Doerte Huscher, David Pittrow, Stephan Rosenkranz, Ekkehard Grünig

    European Respiratory Journal 50 (2) 1700740; DOI: 10.1183/13993003.00740-2017 Published 3 August 2017
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    Risk assessment, prognosis and guideline implementation in pulmonary arterial hypertension

    Athénaïs Boucly, Jason Weatherald, Laurent Savale, Xavier Jaïs, Vincent Cottin, Grégoire Prevot, François Picard, Pascal de Groote, Mitja Jevnikar, Emmanuel Bergot, Ari Chaouat, Céline Chabanne, Arnaud Bourdin, Florence Parent, David Montani, Gérald Simonneau, Marc Humbert, Olivier Sitbon

    European Respiratory Journal 50 (2) 1700889; DOI: 10.1183/13993003.00889-2017 Published 3 August 2017
  • Open Access

    Selexipag for the treatment of connective tissue disease-associated pulmonary arterial hypertension

    Sean Gaine, Kelly Chin, Gerry Coghlan, Richard Channick, Lilla Di Scala, Nazzareno Galiè, Hossein-Ardeschir Ghofrani, Irene M. Lang, Vallerie McLaughlin, Ralph Preiss, Lewis J. Rubin, Gérald Simonneau, Olivier Sitbon, Victor F. Tapson, Marius M. Hoeper

    European Respiratory Journal 50 (2) 1602493; DOI: 10.1183/13993003.02493-2016 Published 17 August 2017

• Interstitial lung diseases

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    Prevalence and incidence of interstitial lung diseases in a multi-ethnic county of Greater Paris

    Boris Duchemann, Isabella Annesi-Maesano, Camille Jacobe de Naurois, Shreosi Sanyal, Pierre-Yves Brillet, Michel Brauner, Marianne Kambouchner, Sophie Huynh, Jean Marc Naccache, Raphael Borie, Jacques Piquet, Arsène Mekinian, Jerôme Virally, Yurdagul Uzunhan, Jacques Cadranel, Bruno Crestani, Olivier Fain, Francois Lhote, Robin Dhote, Nathalie Saidenberg-Kermanac'h, Paul-André Rosental, Dominique Valeyre, Hilario Nunes

    European Respiratory Journal 50 (2) 1602419; DOI: 10.1183/13993003.02419-2016 Published 3 August 2017
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    Immune-checkpoint inhibitors associated with interstitial lung disease in cancer patients

    Myriam Delaunay, Jacques Cadranel, Amélie Lusque, Nicolas Meyer, Valérie Gounant, Denis Moro-Sibilot, Jean-Marie Michot, Judith Raimbourg, Nicolas Girard, Florian Guisier, David Planchard, Anne-Cécile Metivier, Pascale Tomasini, Eric Dansin, Maurice Pérol, Marion Campana, Oliver Gautschi, Martin Früh, Jean-David Fumet, Clarisse Audigier-Valette, Sébastien Couraud, Stéphane Dalle, Marie-Thérèse Leccia, Marion Jaffro, Samia Collot, Grégoire Prévot, Julie Milia, Julien Mazieres

    European Respiratory Journal 50 (2) 1700050; DOI: 10.1183/13993003.00050-2017 Published 10 August 2017
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    Diagnostic accuracy of a clinical diagnosis of idiopathic pulmonary fibrosis: an international case–cohort study

    Simon L.F. Walsh, Toby M. Maher, Martin Kolb, Venerino Poletti, Richard Nusser, Luca Richeldi, Carlo Vancheri, Margaret L. Wilsher, Katerina M. Antoniou, Jüergen Behr, Elisabeth Bendstrup, Kevin Brown, Lucio Calandriello, Tamera J. Corte, Vincent Cottin, Bruno Crestani, Kevin Flaherty, Ian Glaspole, Jan Grutters, Yoshikazu Inoue, Maria Kokosi, Yasuhiro Kondoh, Vasileios Kouranos, Michael Kreuter, Kerri Johannson, Eoin Judge, Brett Ley, George Margaritopoulos, Fernando J. Martinez, Maria Molina-Molina, António Morais, Hilario Nunes, Ganesh Raghu, Christopher J. Ryerson, Moises Selman, Paolo Spagnolo, Hiroyuki Taniguchi, Sara Tomassetti, Dominique Valeyre, Marlies Wijsenbeek, Wim Wuyts, David Hansell, Athol Wells on behalf of The IPF Project Consortium

    European Respiratory Journal 50 (2) 1700936; DOI: 10.1183/13993003.00936-2017 Published 31 August 2017

• Experimental pulmonary fibrosis

  • Open Access

    Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo

    Mareike Lehmann, Martina Korfei, Kathrin Mutze, Stephan Klee, Wioletta Skronska-Wasek, Hani N. Alsafadi, Chiharu Ota, Rita Costa, Herbert B. Schiller, Michael Lindner, Darcy E. Wagner, Andreas Günther, Melanie Königshoff

    European Respiratory Journal 50 (2) 1602367; DOI: 10.1183/13993003.02367-2016 Published 3 August 2017

• Sleep

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    Effect of continuous positive airway pressure on blood pressure and metabolic profile in women with sleep apnoea

    Francisco Campos-Rodriguez, Monica Gonzalez-Martinez, Angeles Sanchez-Armengol, Bernabe Jurado-Gamez, Jose Cordero-Guevara, Nuria Reyes-Nuñez, Maria F. Troncoso, Araceli Abad-Fernandez, Joaquin Teran-Santos, Julian Caballero-Rodriguez, Mercedes Martin-Romero, Ana Encabo-Motiño, Lirios Sacristan-Bou, Javier Navarro-Esteva, Maria Somoza-Gonzalez, Juan F. Masa, Maria A. Sanchez-Quiroga, Beatriz Jara-Chinarro, Belen Orosa-Bertol, Miguel A. Martinez-Garcia on behalf of the Spanish Sleep Network

    European Respiratory Journal 50 (2) 1700257; DOI: 10.1183/13993003.00257-2017 Published 10 August 2017
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    Adaptive servo ventilation for central sleep apnoea in heart failure: SERVE-HF on-treatment analysis

    Holger Woehrle, Martin R. Cowie, Christine Eulenburg, Anna Suling, Christiane Angermann, Marie-Pia d'Ortho, Erland Erdmann, Patrick Levy, Anita K. Simonds, Virend K. Somers, Faiez Zannad, Helmut Teschler, Karl Wegscheider

    European Respiratory Journal 50 (2) 1601692; DOI: 10.1183/13993003.01692-2016 Published 31 August 2017

• COPD

  • Open Access

    Epidemiology and impact of chronic bronchitis in chronic obstructive pulmonary disease

    Lies Lahousse, Leen J.M. Seys, Guy F. Joos, Oscar H. Franco, Bruno H. Stricker, Guy G. Brusselle

    European Respiratory Journal 50 (2) 1602470; DOI: 10.1183/13993003.02470-2016 Published 10 August 2017

• Chronic breathlessness

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    Contributions of a hand-held fan to self-management of chronic breathlessness

    Tim Luckett, Jane Phillips, Miriam J. Johnson, Morag Farquhar, Flavia Swan, Teresa Assen, Priyanka Bhattarai, Sara Booth

    European Respiratory Journal 50 (2) 1700262; DOI: 10.1183/13993003.00262-2017 Published 17 August 2017

• Lung cancer

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    EGFR tyrosine kinase inhibitors versus chemotherapy in EGFR wild-type pre-treated advanced nonsmall cell lung cancer in daily practice

    Pascale Tomasini, Solenn Brosseau, Julien Mazières, Jean-Philippe Merlio, Michèle Beau-Faller, Jean Mosser, Marie Wislez, L'Houcine Ouafik, Benjamin Besse, Isabelle Rouquette, Didier Debieuvre, Fabienne Escande, Virginie Westeel, Clarisse Audigier-Valette, Pascale Missy, Alexandra Langlais, Frank Morin, Denis Moro-Sibilot, Gérard Zalcman, Fabrice Barlesi

    European Respiratory Journal 50 (2) 1700514; DOI: 10.1183/13993003.00514-2017 Published 10 August 2017

• Paediatric pulmonology

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    Neuropsychiatric adverse drug reactions in children initiated on montelukast in real-life practice

    Brigitte Benard, Valérie Bastien, Benjamin Vinet, Roger Yang, Maja Krajinovic, Francine M. Ducharme

    European Respiratory Journal 50 (2) 1700148; DOI: 10.1183/13993003.00148-2017 Published 17 August 2017

• Asthma

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    Airway calibre variation is a major determinant of exhaled nitric oxide's ability to capture asthma control

    Alain Michils, Amaryllis Haccuria, Sebastien Michiels, Alain Van Muylem

    European Respiratory Journal 50 (2) 1700392; DOI: 10.1183/13993003.00392-2017 Published 17 August 2017
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    Fevipiprant, an oral prostaglandin DP₂ receptor (CRTh2) antagonist, in allergic asthma uncontrolled on low-dose inhaled corticosteroids

    Eric D. Bateman, Alfredo G. Guerreros, Florian Brockhaus, Björn Holzhauer, Abhijit Pethe, Richard A. Kay, Robert G. Townley

    European Respiratory Journal 50 (2) 1700670; DOI: 10.1183/13993003.00670-2017 Published 24 August 2017
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    Clinical and biological characteristics of the French COBRA cohort of adult subjects with asthma

    Marina Pretolani, David Soussan, Isabelle Poirier, Gabriel Thabut, Michel Aubier on behalf of the COBRA Study Group

    European Respiratory Journal 50 (2) 1700019; DOI: 10.1183/13993003.00019-2017 Published 24 August 2017
  • Open Access

    Long-term outcomes of bronchial thermoplasty in subjects with severe asthma: a comparison of 3-year follow-up results from two prospective multicentre studies

    Geoffrey Chupp, Michel Laviolette, Lauren Cohn, Charlene McEvoy, Sandeep Bansal, Adrian Shifren, Sumita Khatri, G. Mark Grubb, Edmund McMullen, Racho Strauven, Joel N. Kline

    European Respiratory Journal 50 (2) 1700017; DOI: 10.1183/13993003.00017-2017 Published 31 August 2017

• Tuberculosis

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    Risk of tuberculosis in patients with solid cancers and haematological malignancies: a systematic review and meta-analysis

    Claudia C. Dobler, Kelvin Cheung, John Nguyen, Andrew Martin

    European Respiratory Journal 50 (2) 1700157; DOI: 10.1183/13993003.00157-2017 Published 24 August 2017