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Yield of tuberculosis screening in asylum-seekers by country of origin: analysis of screening data in a German federal state (2002–2015)

Kayvan Bozorgmehr, Brigitte Joggerst, Ulrich Wagner, Christian Stock
European Respiratory Journal 2017 49: 1602327; DOI: 10.1183/13993003.02327-2016
Kayvan Bozorgmehr
1Dept of General Practice and Health Services Research, University Hospital Heidelberg, Heidelberg, Germany
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  • For correspondence: kayvan.bozorgmehr@med.uni-heidelberg.de
Brigitte Joggerst
2Public Health Authority, Pforzheim, Germany
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Ulrich Wagner
3Public Health Authority, Section for Disease Control, Karlsruhe, Germany
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Christian Stock
4Institute of Medical Biometry and Informatics, University Hospital Heidelberg, Heidelberg, Germany
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Tables

  • Supplementary Materials
  • TABLE 1

    Yield of screening, number needed to screen, and relative rates of yield obtained from Bayesian Poisson regression models

    CharacteristicNCases with active TB detectedYield of active TB per 100 000 screened (95% CrI)Number needed to screen to detect 1 case of active TB (95% CrI)Relative risk (95% CrI)
    Mutually adjusted model I: countries >5 cases versus otherMutually adjusted model II: countries with >5000 screened versus other
    Age group
     <15 years24 249416 (6, 39)6062 (2550, 17 959)0.20 (0.08, 0.64)0.22 (0.07, 0.59)
     15–24 years35 3903599 (70, 136)1011 (736, 1427)0.74 (0.48, 1.16)0.85 (0.55, 1.31)
     25–44 years51 11156110 (84, 141)913 (708, 1196)Ref.Ref.
     45–64 years7583340 (11, 106)2528 (947, 8974)0.48 (0.13, 1.42)0.45 (0.11, 1.31)
     >64 years61600.06 (<0.01, 3.11)0.03 (1.18, 3.94)
    Sex
     Female36 8721335 (20, 59)2836 (1707, 5060)Ref.Ref.
     Male82 05185104 (83, 127)965 (785, 1200)2.09 (1.17, 3.97)2.09 (1.15, 3.96)
    Year
     2002–201236 64741112 (81, 150)894 (666, 1228)Ref.Ref.
     201314 407749 (22, 95)2058 (1048, 4601)0.42 (0.17, 0.91)0.48 (0.20, 1.05)
     201423 91624100 (66, 147)997 (681, 1516)0.65 (0.36, 1.17)0.99 (0.58, 1.68)
     201544 0672659 (39, 85)1695 (1175, 2534)0.52 (0.30, 0.90)0.68 (0.40, 1.14)
    Country#
     Afghanistan7433227 (6, 86)3716 (1159, 17 883)0.22 (0.04, 0.82)
     Cameroon25065200 (76, 437)501 (229, 1313)2.70 (0.90, 6.68)
     Eritrea19419464 (230, 845)216 (118, 435)8.95 (3.83, 19.77)
     Gambia697118258 (159, 399)387 (251, 630)4.53 (2.42, 8.37)1.78 (0.99, 3.15)
     Georgia21215236 (90, 516)424 (194, 1111)4.05 (1.37, 10.26)
     Iraq9955110 (1, 47)9955 (2130, 92 262)0.06 (<0.01, 0.36)
     Kosovo20 336734 (15, 68)2905 (1480, 6494)0.86 (0.34, 1.91)0.37 (0.15, 0.80)
     Macedonia7005229 (6, 92)3502 (1092, 16 854)0.31 (0.06, 1.14)
     Pakistan51037137 (61, 269)729 (372, 1629)1.88 (0.74, 4.17)0.87 (0.37, 1.84)
     Russia30265165 (63, 362)605 (276, 1585)3.17 (1.07, 7.90)
     Somalia10257683 (306, 1336)146 (75, 327)11.85 (4.70, 26.65)
     Syria17 172529 (11, 64)3434 (1567, 9000)0.67 (0.22, 1.68)0.27 (0.09, 0.65)
     OtherRef.Ref.
    • The Watanabe-Akaike information criterion (WAIC) was 304 in the mutually adjusted model I and 260 in the mutually adjusted model II. Lower values of the WAIC indicate a better prediction model. #: countries with either ≥5 cases of active tuberculosis (TB) detected or more than 5000 individuals screened. RR: relative risk; CrI: credible interval.

Supplementary Materials

  • Tables
  • Supplementary Material

    K. Bozorgmehr ERJ-02327-2016_Bozorgmehr

    B. Joggerst ERJ-02327-2016_Joggerst

    C. Stock ERJ-02327-2016_Stock

    U. Wagner ERJ-02327-2016_Wagner

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Yield of tuberculosis screening in asylum-seekers by country of origin: analysis of screening data in a German federal state (2002–2015)
Kayvan Bozorgmehr, Brigitte Joggerst, Ulrich Wagner, Christian Stock
European Respiratory Journal Apr 2017, 49 (4) 1602327; DOI: 10.1183/13993003.02327-2016

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Yield of tuberculosis screening in asylum-seekers by country of origin: analysis of screening data in a German federal state (2002–2015)
Kayvan Bozorgmehr, Brigitte Joggerst, Ulrich Wagner, Christian Stock
European Respiratory Journal Apr 2017, 49 (4) 1602327; DOI: 10.1183/13993003.02327-2016
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