Devices n | 876 | 452 | 598 | 422 | 625 | 420 |
Dose preparation critical errors | | | | | | |
Lack of cartridge or no capsule in device prior to inhalation | 3 (0.3) | | 5 (0.8) | | 35 (5.6) | |
Inhalation despite dose counter at zero | | 20 (4.4) | | | 37 (5.9) | 16 (3.8) |
Opening next blister when taking the capsule | | | 34 (5.7) | | | |
Activation error (not pressing button, twisting error, loading position error, not sliding lever, opening mouthpiece) | 4 (0.5) | 9 (2.0) | 18 (3.0) | | 7 (1.1) | 86 (20.5) |
Total dose preparation critical error [95% CI] | 7 (0.8) [0.3–1.6] | 29 (6.4) [4.2–8.7] | 48 (8.0) [5.8–10.2] | – | 78 (12.5) [9.9–15.1] | 100 (23.8) [19.7–27.9] |
Dose delivery critical errors | | | | | | |
Expiration in powder device prior inhalation | 87 (9.9) | 60 (13.3) | 60 (10.0) | | | 36 (8.6) |
No inspiration through the mouthpiece | 21 (2.4) | 15 (3.3) | 22 (3.7) | 7 (1.7) | 11 (1.8) | 14 (3.3) |
Remaining powder in the capsule by the end | 33 (3.8) | | 80 (13.4) | | | |
Lack of synchronisation hand–lung with smoke emanation | | | | 181 (42.9) | 246 (39.4) | |
Total dose delivery critical error [95% CI] | 131 (15.0) [12.6–17.3] | 70 (15.5) [12.2–18.8] | 149 (24.9) [21.4–28.4] | 185 (43.8) [39.1–48.6] | 249 (39.8) [36–43.7] | 48 (11.4) [8.4–14.5] |