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Contribution of PIPE Score on prognostic evaluation of idiopathic pleural effusions (IPE)

Maria Alejandra Galarza Jimenez, Esteban Pérez-Rodríguez, Paola Lucía Arrieta-Narváez, Rosa Mariela Mirambeaux-Villalona, Patricia Castro-Acosta, Beatriz Martín-García, Ana Soledad Jaureguizar-Oriol
European Respiratory Journal 2016 48: PA5042; DOI: 10.1183/13993003.congress-2016.PA5042
Maria Alejandra Galarza Jimenez
1Pneumology Department, Ramón y Cajal Hospital, Madrid, Spain
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Esteban Pérez-Rodríguez
1Pneumology Department, Ramón y Cajal Hospital, Madrid, Spain
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Paola Lucía Arrieta-Narváez
1Pneumology Department, Ramón y Cajal Hospital, Madrid, Spain
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Rosa Mariela Mirambeaux-Villalona
1Pneumology Department, Ramón y Cajal Hospital, Madrid, Spain
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Patricia Castro-Acosta
1Pneumology Department, Ramón y Cajal Hospital, Madrid, Spain
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Beatriz Martín-García
1Pneumology Department, Ramón y Cajal Hospital, Madrid, Spain
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Ana Soledad Jaureguizar-Oriol
1Pneumology Department, Ramón y Cajal Hospital, Madrid, Spain
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Abstract

IPEs are difficult to interpret and often need not always diagnostic but difficult indication thoracoscopy

Assess the contribution of PIPE (prognostic in idiopathic pleural effusions) Score to predict malignancy

Quantify window period of dx of malignancy and histological filliation

1994-2015 6894 PE has been analyzed 3361 in our database

IPE in 76 patients(3,79%) dx was revalued after 3 years of pursuit

Retrospective analysis, meaning and predictive values of benign(Bx)/malignant(Mx) course

49 males(64.5%)/27 women(35.5%)

Age 68.5+/-4.7

After 3 years 12 Mx and 60 Bx

Eosinophilia<10% 19.14% ended being Mx and >=10% 10.02%(p=0.30)

Age>=70 ended being Mx 20% and <70 9.67%(p=0.22)

Ended up Mx 21.05% with dx pretest Mx and 10.52% with dx pretest Bx(p=0.20)

Window period between dx and identification of malignancy was 7,72+/-7months

Histological filliation mostly lung

Analyzed variables were not significant but showed tendency

The impact of these according to degree of weighting allowed to develop a predictive score: PIPE Score

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IPEs are mostly Bx course

Parameters most frequently associated with Mx course were ADE

Period window between IPE dx and occurrence of malignancy was 7months the pulmonary origin were in half cases

PIPE Score could help us decide more individualized dx progression in some patients

We require multicenter studies and validation of protocol of monitoring for IPE with low score.

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Contribution of PIPE Score on prognostic evaluation of idiopathic pleural effusions (IPE)
Maria Alejandra Galarza Jimenez, Esteban Pérez-Rodríguez, Paola Lucía Arrieta-Narváez, Rosa Mariela Mirambeaux-Villalona, Patricia Castro-Acosta, Beatriz Martín-García, Ana Soledad Jaureguizar-Oriol
European Respiratory Journal Sep 2016, 48 (suppl 60) PA5042; DOI: 10.1183/13993003.congress-2016.PA5042

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Contribution of PIPE Score on prognostic evaluation of idiopathic pleural effusions (IPE)
Maria Alejandra Galarza Jimenez, Esteban Pérez-Rodríguez, Paola Lucía Arrieta-Narváez, Rosa Mariela Mirambeaux-Villalona, Patricia Castro-Acosta, Beatriz Martín-García, Ana Soledad Jaureguizar-Oriol
European Respiratory Journal Sep 2016, 48 (suppl 60) PA5042; DOI: 10.1183/13993003.congress-2016.PA5042
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