Abstract
IPEs are difficult to interpret and often need not always diagnostic but difficult indication thoracoscopy
Assess the contribution of PIPE (prognostic in idiopathic pleural effusions) Score to predict malignancy
Quantify window period of dx of malignancy and histological filliation
1994-2015 6894 PE has been analyzed 3361 in our database
IPE in 76 patients(3,79%) dx was revalued after 3 years of pursuit
Retrospective analysis, meaning and predictive values of benign(Bx)/malignant(Mx) course
49 males(64.5%)/27 women(35.5%)
Age 68.5+/-4.7
After 3 years 12 Mx and 60 Bx
Eosinophilia<10% 19.14% ended being Mx and >=10% 10.02%(p=0.30)
Age>=70 ended being Mx 20% and <70 9.67%(p=0.22)
Ended up Mx 21.05% with dx pretest Mx and 10.52% with dx pretest Bx(p=0.20)
Window period between dx and identification of malignancy was 7,72+/-7months
Histological filliation mostly lung
Analyzed variables were not significant but showed tendency
The impact of these according to degree of weighting allowed to develop a predictive score: PIPE Score
IPEs are mostly Bx course
Parameters most frequently associated with Mx course were ADE
Period window between IPE dx and occurrence of malignancy was 7months the pulmonary origin were in half cases
PIPE Score could help us decide more individualized dx progression in some patients
We require multicenter studies and validation of protocol of monitoring for IPE with low score.
- Copyright ©the authors 2016