Abstract
Background: Autonomic function impairments have been widely reported in patients with COPD. However, a description of an autonomic symptom profile for these patients is currently lacking.
Aims and objectives: The objective of this study was to provide a profile of COPD patients with autonomic symptoms. Hence, we examined the presence of autonomic symptoms in COPD and their association with levels of anxiety, depression, health status, fatigue, dyspnea, respiratory and demographic parameters.
Methods: Autonomic complaints were evaluated in 53 COPD patients using the autonomic symptom profile (ASP). General health status was assessed using the hospital anxiety and depression scale, the short-form 36, and the checklist individual strength which assess fatigue. Respiratory outcomes (FEV1, FVC, PEF & dyspnea) and demographic variables (age, BMI, weight & height) were also collected. Spearman rho coefficients were calculated (p<0.05).
Results: In subjects with COPD, autonomic symptoms were present and associated with high levels of anxiety, depression and worsened mental health. The presence of severe autonomic symptoms was also associated with poor physical health and higher levels of fatigue. There were no correlations between the overall ASP profile and demographic or respiratory parameters. However, a diminished papillomotor function was mildly associated with reduced FEV1.
Conclusions: Autonomic complaints are prevalent in subjects with COPD especially in those who have higher levels of anxiety, depression, fatigue, and poor general health. This highlights the need for screening autonomic function in COPD patients who fit this profile and their treatment should be adapted accordingly.
- Copyright ©the authors 2016
