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Efficacy of air purifier for adjuvant therapy of asthma

Jaiying Luo, Zhao Chen, Xiao Lan, Jiaqing HU, Baoqing Sun
European Respiratory Journal 2016 48: PA4204; DOI: 10.1183/13993003.congress-2016.PA4204
Jaiying Luo
1State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, Guangzhou, China
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Zhao Chen
2State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, China
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Xiao Lan
2State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, China
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Jiaqing HU
2State Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, China
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Baoqing Sun
1State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Disease, Guangzhou, China
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Abstract

Background: Patients with well-controlled asthma, which lead to a reduction in symptoms and medication use, can have a better quality of life. In this study, we determined particulate matter (PM2.5 and PM10) concentration in the air of the bedroom and outdoor, and house dust mite (HDM) allergen concentrations in the bedding and pillows, before and after applying the HEPA air purifier, to evaluate its effect to improve air quality and its efficacy for adjuvant therapy of asthma.

Methods: Air purifier was set near the bed for 3 months. 11 children and 7 adults that were 7∼42 years old and diagnosed with asthma were selected. Before and after application of the purifier, dust sample was collected, indoor and outdoor PM value was measured. The change in PM values was shown in PM indoor/outdoor ratio. In addition, ACT & CACT was used to access the symptoms of the patients. SPSS21.0 was used for data entry and analysis, measurement data was descriptively analyzed, Non-parametric test and repeated measurement ANOVA were used to comparison among groups, P<0.05 was considered statistically significant.

Results: 1 Der p1(80.74(77.78,84.07)ng/g)was the most abundant allergen in air of the patient's bedroom, followed by Der f1(29.63(29.63,63.33)ng/g); Der f1 concentration(370.81(282.80,579.25)ng/g)in bedding and pillows was higher than Der p1 4.74(203.43(33.63,1006.60)ng/g)g/g. 2 Der f1 and Der p1 concentration slightly decreased after application of the air purifier. 3 PM2.5, PM10 concentration significantly decreased in three months. 4 Patients' score for ACT&CACT shows not statistically significant before or use the air purifier.

Conclusion: Air purifier can effectively reduce PM and HDM allergen concentrations in the air.

  • Asthma - management
  • Environment
  • Immunology
  • Copyright ©the authors 2016
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Efficacy of air purifier for adjuvant therapy of asthma
Jaiying Luo, Zhao Chen, Xiao Lan, Jiaqing HU, Baoqing Sun
European Respiratory Journal Sep 2016, 48 (suppl 60) PA4204; DOI: 10.1183/13993003.congress-2016.PA4204

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Efficacy of air purifier for adjuvant therapy of asthma
Jaiying Luo, Zhao Chen, Xiao Lan, Jiaqing HU, Baoqing Sun
European Respiratory Journal Sep 2016, 48 (suppl 60) PA4204; DOI: 10.1183/13993003.congress-2016.PA4204
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