Abstract
Objective: Evaluation of pulmonary changes on chest CT examinations in premature born children with bronchopulmonary dysplasia.
Methods: The study population consists of 10 premature born children with bronchopulmonary dysplasia, of whom 60%:95%CI, 26,2-87,8 boys, and 40%:
95%CI, 12,2-73,8 girls. The control group – prematurely born 5 children, who have not progressed bronchopulmonary dysplasia. HRCT examinations were performed with 80-slice CT-scanner Aquilion Prime (Toshiba).
Results: Children diagnosed with bronchopulmonary dysplasia were born with mean gestational age and birth weight were 25,5±1,4 weeks gestation and 1128,7±101,4g, respectively. The control group – mean gestational age and birth weight were 29,5±1,2 weeks gestation and 1535,4±152,5g (p<0,05), respectively.
All 10 children developed a respiratory distress syndrome, of whom 8 children were treated with CPAP therapy with mean duration of 13,25±0,25 days, and 2 children – were on mechanical ventilation with mean duration of 5,7±3,45 days.
Chest high-resolution CT findings in premature born children with bronchopulmonary dysplasia were the following: reticular interstitial pattern (90%: 95%CI, 40-97,2), subpleural triangular opacities (60%:95%CI,29,9-92,5), hyperattenuated areas with mosaic distribution (50%:95%CI,13,7-78,8). All these findings were absent in the control group, in wich just signs of hyperexpansion or emphysema were found.
Conclusion: Bronchopulmonary dysplasia in premature born children has shown a progressive evolution correlated with the following CT findings: reticular interstitial pattern, subpleural triangular opacities, hyperattenuated areas with mosaic distribution.
- Copyright ©the authors 2016