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Validation of the multi-independence dimensions (MIND) questionnaire for prolonged mechanical ventilated patients

Javier Murcia, Joao Winck, Hélène Gilet, Peter Kalin, Fabian Plano, Antoine Regnault, Michael Dreher, Michele Vitacca, Nicolino Ambrosino
European Respiratory Journal 2016 48: PA3768; DOI: 10.1183/13993003.congress-2016.PA3768
Javier Murcia
1Healthcare, Linde Colombia, Bogotá, Colombia
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Joao Winck
2Linde Healthcare, Linde AG, Pullach, Germany
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Hélène Gilet
3Mapi HEOR & Strategic Market Access, Mapi, Lyon, France
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Peter Kalin
4Linde Gas Therapeutics GmbH, Linde Healthcare, Oberschleissheim, Germany
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Fabian Plano
5REMEO Centre el Pilar, Linde Healthcare, Pilar, Argentina
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Antoine Regnault
3Mapi HEOR & Strategic Market Access, Mapi, Lyon, France
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Michael Dreher
6Department of Cardiology, Pneumology, Angiology and Intensive Care Medicine, University Hospital Aachen, Aachen, Germany
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Michele Vitacca
7Respiratory and Rehabilitation Division, Fondazione S. Maugeri, IRCCS, Lumezzane, Italy
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Nicolino Ambrosino
8Center of Respiratory Weaning and Rehabilitation, Auxilium Vitae, Volterra, Italy
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Abstract

Background: No severity-of-illness scoring system has been specifically designed for patients under prolonged mechanical ventilation (PMV).

Objective: To validate the Multi-INdependence Dimensions (MIND) questionnaire, a comprehensive measure of health status of PMV patients.

Methods: The MIND questionnaire was composed of 11 components developed from a Delphi panel and existing measures. Key components were: cognition, feeding/swallowing, sleep, skin integrity, oxygenation, cough strength, secretion management, mobility, upper and lower limb strength, ventilator dependence and co-morbidities. The questionnaire was tested in patients admitted to 5 weaning facilities in 3 countries (Argentina, Colombia and Germany). MIND, Medical Research Council (MRC) muscle strength score, Sepsis-related Organ Failure Assessment (SOFA), Glasgow Coma Scale (GCS), Dependence Nursing Scale (DNS) and EuroQol-5 Dimension (EQ-5D) were evaluated at inclusion. MIND and clinician global impression of change (CGIC) were evaluated after one day and 30 days after inclusion.

Results: 128 patients (65 (SD=15.5) years) were included; 50% male; 34.4% COPD/Chronic Lung Disease, 18.8% Neuromuscular Disorders, 10.9% Cerebrovascular Disorders and 9.4% Cardiovascular Disorders. Four composite scores were created. All scores showed good test-retest reliability and correlated meaningfully with MRC score, SOFA, DNS, GCS and EQ-5D, supporting their validity. MIND scores were able to detect improvement in patient health status.

Conclusion: The MIND questionnaire is a valid and reliable instrument for measuring comprehensively the multiple dimensions characterizing the health status of PMV patients.

  • Mechanical ventilation - ventilator-associated
  • Monitoring
  • Quality of life
  • Copyright ©the authors 2016
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Validation of the multi-independence dimensions (MIND) questionnaire for prolonged mechanical ventilated patients
Javier Murcia, Joao Winck, Hélène Gilet, Peter Kalin, Fabian Plano, Antoine Regnault, Michael Dreher, Michele Vitacca, Nicolino Ambrosino
European Respiratory Journal Sep 2016, 48 (suppl 60) PA3768; DOI: 10.1183/13993003.congress-2016.PA3768

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Validation of the multi-independence dimensions (MIND) questionnaire for prolonged mechanical ventilated patients
Javier Murcia, Joao Winck, Hélène Gilet, Peter Kalin, Fabian Plano, Antoine Regnault, Michael Dreher, Michele Vitacca, Nicolino Ambrosino
European Respiratory Journal Sep 2016, 48 (suppl 60) PA3768; DOI: 10.1183/13993003.congress-2016.PA3768
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