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Prevalence of ocular sarcoidosis in patients with intra thoracic sarcoidosis

Muhammad Hussain, Hazim Mahdi, Mohammed Hassan
European Respiratory Journal 2016 48: PA3730; DOI: 10.1183/13993003.congress-2016.PA3730
Muhammad Hussain
1Respiratory Medicine, Doncaster Royal Infirmary, Doncaster, United Kingdom
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Hazim Mahdi
2Respiratory Medicine, Barnsley DG Hospital, Barnsley, South YorkshireUnited Kingdom
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Mohammed Hassan
3Opthalmology, Barnsley DG Hospital, Barnsley, South YorkshireUnited Kingdom
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Abstract

Introduction: Sarcoidosis is an inflammatory multi system granulomatous disease of unknown etiology. Diagnosis of sarcoid is established on the basis of compatible history, clinical & radiological findings, supported by histological evidence of non caseating granuloma. The eye & adnexa are involved in 25-80% of patients with sarcoidosis. Literature review does indicate that conjuntival biopsy carries low morbidity with high positive yield.

Material & Method: Proforma designed. All diagnosed sarcoid patients were subjected to detail ophthalmology history & examination.

Results: 52 cases were registered during study period. 47 included as 5 had incomplete information as per proforma.

Age & Sex;: 24(51%) had eye symptoms 35(74%) consented for eye examination. 13(37%) of them had abnormal finding on ocular examination.

AGENumberMaleFemale
21- 4016133
41-60251213
Above 60615

AGE & Gender

SymptomsNumber
Dry Eye8
Blurring of Vision6
Red Eye2
Pain & Red5
Dry & Red3

Eye Symptoms

Discussion: 76.6.% had histological diagnosis. 23 out of 36 had bronchoscopy/EBUS..

Study revealed fairly high prevalence of ocular symptoms amongest sarcoid patients (51%) & 37% of them had abnormal eye examination finding. Non of our patient had conjunctival biopsy. literature review indicate that conjunctival biopsy is positive in up to 66% of cases with conjunctival follicles & up to 31% without it. conjunctival biopsy in presence of pulmonary infiltrate is reported to be positive in 51.6% patients.

Considering our study finding we may conclude that requesting conjuntival biopsy will reduced our need of transbronchial /EBUS need. This will be cost effective & more convenient for the patients.

  • Sarcoidosis
  • Extrapulmonary impact
  • Copyright ©the authors 2016
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Prevalence of ocular sarcoidosis in patients with intra thoracic sarcoidosis
Muhammad Hussain, Hazim Mahdi, Mohammed Hassan
European Respiratory Journal Sep 2016, 48 (suppl 60) PA3730; DOI: 10.1183/13993003.congress-2016.PA3730

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Prevalence of ocular sarcoidosis in patients with intra thoracic sarcoidosis
Muhammad Hussain, Hazim Mahdi, Mohammed Hassan
European Respiratory Journal Sep 2016, 48 (suppl 60) PA3730; DOI: 10.1183/13993003.congress-2016.PA3730
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