Abstract
Introduction: Sarcoidosis is an inflammatory multi system granulomatous disease of unknown etiology. Diagnosis of sarcoid is established on the basis of compatible history, clinical & radiological findings, supported by histological evidence of non caseating granuloma. The eye & adnexa are involved in 25-80% of patients with sarcoidosis. Literature review does indicate that conjuntival biopsy carries low morbidity with high positive yield.
Material & Method: Proforma designed. All diagnosed sarcoid patients were subjected to detail ophthalmology history & examination.
Results: 52 cases were registered during study period. 47 included as 5 had incomplete information as per proforma.
Age & Sex;: 24(51%) had eye symptoms 35(74%) consented for eye examination. 13(37%) of them had abnormal finding on ocular examination.
| AGE | Number | Male | Female |
| 21- 40 | 16 | 13 | 3 |
| 41-60 | 25 | 12 | 13 |
| Above 60 | 6 | 1 | 5 |
AGE & Gender
| Symptoms | Number |
| Dry Eye | 8 |
| Blurring of Vision | 6 |
| Red Eye | 2 |
| Pain & Red | 5 |
| Dry & Red | 3 |
Eye Symptoms
Discussion: 76.6.% had histological diagnosis. 23 out of 36 had bronchoscopy/EBUS..
Study revealed fairly high prevalence of ocular symptoms amongest sarcoid patients (51%) & 37% of them had abnormal eye examination finding. Non of our patient had conjunctival biopsy. literature review indicate that conjunctival biopsy is positive in up to 66% of cases with conjunctival follicles & up to 31% without it. conjunctival biopsy in presence of pulmonary infiltrate is reported to be positive in 51.6% patients.
Considering our study finding we may conclude that requesting conjuntival biopsy will reduced our need of transbronchial /EBUS need. This will be cost effective & more convenient for the patients.
- Copyright ©the authors 2016
