Skip to main content

Main menu

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • For authors
    • Instructions for authors
    • Submit a manuscript
    • Author FAQs
    • Open access
    • COVID-19 submission information
  • Alerts
  • Podcasts
  • Subscriptions
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

User menu

  • Log in
  • Subscribe
  • Contact Us
  • My Cart

Search

  • Advanced search
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

Login

European Respiratory Society

Advanced Search

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • For authors
    • Instructions for authors
    • Submit a manuscript
    • Author FAQs
    • Open access
    • COVID-19 submission information
  • Alerts
  • Podcasts
  • Subscriptions

The efficacy of high-flow nasal cannulae oxygen therapy in severe acute exacerbation of chronic obstructive pulmonary disease: A randomized controlled trial

Myoung Kyu Lee, Sang-Ha Kim, Won-Yeon Lee, Suk Joong Yong, Seok Jeong Lee, Ye-Ryung Jung
European Respiratory Journal 2016 48: PA3058; DOI: 10.1183/13993003.congress-2016.PA3058
Myoung Kyu Lee
1Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sang-Ha Kim
1Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Won-Yeon Lee
1Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Suk Joong Yong
1Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Seok Jeong Lee
1Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ye-Ryung Jung
1Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
Loading

Abstract

High flow nasal cannulae (HFNC) oxygen therapy has demonstrated an effect comparable with non-invasive ventilation (NIV). We conducted the prospective randomized controlled study to compare the effectiveness between the HFNC and NIV in severe AECOPD with moderate hypercapnic acute respiratory failure.

We enrolled the patients who hospitalized with severe AECOPD from January 2013 to February 2015. Each group of eligible patients received HFNC or NIV oxygen therapy respectively. The primary end point was the 30-day mortality. Treatment failure was defined that the patients underwent intubation with mechanical ventilation due to continuous hypoxia and hypercapnia despite of HFNC or NIV.

Finally 68 patients underwent randomization. The mean age was 72.4 ± 9.5 years. The 30-day mortality was 22.2% on HFNC and 28.1% on NIV group, and treatment failure was 33.3% on HFNC and 50.0% on NIV groups, respectively. Hypercapnia was more improved in HFNC oxygen therapy group than NIV group in severe AECOPD with respiratory failure HFNC oxygen therapy may be alternative to NIV therapy in severe AECOPD.

Figure1
  • Download figure
  • Open in new tab
  • Download powerpoint
Figure2
  • Download figure
  • Open in new tab
  • Download powerpoint
  • COPD - exacerbations
  • Non-invasive ventilation - acute respiratory failure
  • Oxygen therapy
  • Copyright ©the authors 2016
Previous
Back to top
Vol 48 Issue suppl 60 Table of Contents
  • Table of Contents
  • Index by author
Email

Thank you for your interest in spreading the word on European Respiratory Society .

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
The efficacy of high-flow nasal cannulae oxygen therapy in severe acute exacerbation of chronic obstructive pulmonary disease: A randomized controlled trial
(Your Name) has sent you a message from European Respiratory Society
(Your Name) thought you would like to see the European Respiratory Society web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Alerts
Sign In to Email Alerts with your Email Address
Citation Tools
The efficacy of high-flow nasal cannulae oxygen therapy in severe acute exacerbation of chronic obstructive pulmonary disease: A randomized controlled trial
Myoung Kyu Lee, Sang-Ha Kim, Won-Yeon Lee, Suk Joong Yong, Seok Jeong Lee, Ye-Ryung Jung
European Respiratory Journal Sep 2016, 48 (suppl 60) PA3058; DOI: 10.1183/13993003.congress-2016.PA3058

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
The efficacy of high-flow nasal cannulae oxygen therapy in severe acute exacerbation of chronic obstructive pulmonary disease: A randomized controlled trial
Myoung Kyu Lee, Sang-Ha Kim, Won-Yeon Lee, Suk Joong Yong, Seok Jeong Lee, Ye-Ryung Jung
European Respiratory Journal Sep 2016, 48 (suppl 60) PA3058; DOI: 10.1183/13993003.congress-2016.PA3058
del.icio.us logo Digg logo Reddit logo Technorati logo Twitter logo CiteULike logo Connotea logo Facebook logo Google logo Mendeley logo

Jump To

  • Article
  • Figures & Data
  • Info & Metrics
  • Tweet Widget
  • Facebook Like
  • Google Plus One

More in this TOC Section

  • Effects of continuous positive airway pressure on arterial stiffness and oxidative stress in patients with obstructive sleep apnoea
  • Telemonitoring to optimise care in motor neurone disease: A pilot study
  • Short-term effects, long-term compliance and admissions in patients with obesity hypoventilation syndrome under noninvasive mechanical ventilation
Show more 2.2 Noninvasive Ventilatory Support

Related Articles

Navigate

  • Home
  • Current issue
  • Archive

About the ERJ

  • Journal information
  • Editorial board
  • Reviewers
  • CME
  • Press
  • Permissions and reprints
  • Advertising

The European Respiratory Society

  • Society home
  • myERS
  • Privacy policy
  • Accessibility

ERS publications

  • European Respiratory Journal
  • ERJ Open Research
  • European Respiratory Review
  • Breathe
  • ERS books online
  • ERS Bookshop

Help

  • Feedback

For authors

  • Instructions for authors
  • Submit a manuscript
  • ERS author centre

For readers

  • Alerts
  • Subjects
  • Podcasts
  • RSS

Subscriptions

  • Accessing the ERS publications

Contact us

European Respiratory Society
442 Glossop Road
Sheffield S10 2PX
United Kingdom
Tel: +44 114 2672860
Email: journals@ersnet.org

ISSN

Print ISSN:  0903-1936
Online ISSN: 1399-3003

Copyright © 2021 by the European Respiratory Society