Abstract
As previous studies have shown Interstitial lung diseases(ILD)would be a risk factor for lung cancer(LC)development
OBJECTIVES: Describing our population of patients with concomitant ILD and LC as well as knowing their survival
MATERIAL AND METHODS: Prospective study started in 2012 comprising 41 patients with ILD and LC revised in ILD consult(25%)or LC consult(75%).The variables included were age,sex,smoking habit,radiological ILD pattern,FVC,DLCO,histology,tumor localization,stage,treatment and time until death
RESULTS: The average age was 71.9±8.4;95% were male.70% ex-smokers and 30% smokers.The radiological patterns were:20 UIP,8 possible UIP,8 inconsistent UIP,4 NSIP and 1 LCH.The average FVC was 94±19 and DLCO 50±16.Most tumors(61%)were located in the upper lobes.3 patients were not biopsy-proven,16 squamous cell carcinoma,11 ADC,8 SCLC and 3 NOS carcinoma.20 patients were diagnosed in stages I and II and 21 in stages III and IV.Only 4 patients underwent surgery,5 chemotherapy,5 radiotherapy,16 combined treatment and 11 palliative treatment.There were 23 deaths(average time to death 5.3 months±4.5).No statistically significant differences in mean time to death between different radiological patterns of ILD were shown.
CONCLUSIONS: LC represents a major comorbidity in ILD patients,mainly in those with UIP pattern
Concomitance of ILD and LC has an adverse impact on survival.There was no difference in mean survival between the different radiological patterns of ILD.
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