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Modern characteristics of childhood tuberculosis

Valentyn Polyakov, Iryna Sirenko, Lidiia Sukhanova, Olga Marchenko, Kateryna Levchenko, Oleksandr Onikiienko
European Respiratory Journal 2016 48: PA2741; DOI: 10.1183/13993003.congress-2016.PA2741
Valentyn Polyakov
1Department of Pediatric Phthisiatry and Pulmonology, Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine
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Iryna Sirenko
1Department of Pediatric Phthisiatry and Pulmonology, Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine
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Lidiia Sukhanova
1Department of Pediatric Phthisiatry and Pulmonology, Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine
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Olga Marchenko
1Department of Pediatric Phthisiatry and Pulmonology, Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine
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Kateryna Levchenko
1Department of Pediatric Phthisiatry and Pulmonology, Kharkiv Medical Academy of Postgraduate Education, Kharkiv, Ukraine
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Oleksandr Onikiienko
2Department of Pediatric #1 and Neonatology, Kharkiv National Medical University, Kharkiv, Ukraine
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Abstract

Aim: To study the characteristics of tuberculosis (TB) in children.

Materials and methods: We examined 107 children with TB in Regional children tuberculous department, using clinical, radiological and bacteriological methods. Among them 63 (59%) boys and 44 (41%) girls. Children aged 0-5 years 36%, 6-10 years - 7%, 11-14 years - 11%, 15-17 years - 46%.

Results: TB of intrathoracic lymph nodes was detected in 22% of children, primary tuberculous complex - 21% of children. These forms are diagnosed in patients aged upto 5 years. Infiltrative TB was observed in 35% of children, mostly aged 15-17 years. Focal tuberculosis was detected in 3%, tuberculous pleuritis in 14% of children and 2% had tuberculous meningitis.

Mycobacterium tuberculosis was detected in 39 (36%) of children by culture, among them in 13 patents bacterioscopical investigation was also positive. In 16 (15%) patients were identified multidrug-resistant TB (MDR-TB), and their treatment was carried out second-line drugs.

Among 24 children with tuberculosis of intrathoracic lymph nodes cultural test was positive in 4 (17%) patients, 2 of them had MDR-TB.

10 of 22 children with primary tuberculous complex had microbiologic confirmation of TB, of whom 5 kids had MDR-TB. Among 41 child with infiltrative pulmonary tuberculosis MBT was found in 24 (59%) children, of whom 9 patients had MDR-TB. 6 patients with tuberculous pleuritis had positive culture test of the pleural fluid.

Conclusions: nowadays tuberculosis affects more commonly children aged 0-5 years (36%) and teenagers (46%); positive culture test and microscopy was detected in 36% of patients, predominantly in those who had lung parenchyma affection; multidrug-resistant tuberculosis was detected in 15% of children.

  • MDR-TB
  • Tuberculosis - diagnosis
  • Copyright ©the authors 2016
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Modern characteristics of childhood tuberculosis
Valentyn Polyakov, Iryna Sirenko, Lidiia Sukhanova, Olga Marchenko, Kateryna Levchenko, Oleksandr Onikiienko
European Respiratory Journal Sep 2016, 48 (suppl 60) PA2741; DOI: 10.1183/13993003.congress-2016.PA2741

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Modern characteristics of childhood tuberculosis
Valentyn Polyakov, Iryna Sirenko, Lidiia Sukhanova, Olga Marchenko, Kateryna Levchenko, Oleksandr Onikiienko
European Respiratory Journal Sep 2016, 48 (suppl 60) PA2741; DOI: 10.1183/13993003.congress-2016.PA2741
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