Abstract
Introduction: Post tuberculosis obstructive airway disease(post-TB OAD) is a known etiology for chronic obstructive pulmonary disease (COPD).1. No study compares change in lung functions in post-TB OAD to that in COPD. Aims and Objectives: To compare the annual change in forced expiratory volume in first second (FEV1) in post-TB OAD to that in COPD.
Materials and Methods: All diagnosed cases of COPD and post-TB OAD with FEV1/FVC ratio <0.7 presenting in outpatient department underwent spirometry twice at 1 year interval. Both the groups were on optimised treatment during that 1 year. The annual changes in absolute values of both pre and post bronchodilator FEV1 in post-TB OAD were compared to that in COPD.
Results: There were a total of 65 patients with 34 having post-TB OAD and remaining 31 having COPD. Mean age were 57 years for post-TB OAD and 63 years for COPD. 31% were females in post-TB OAD against 41% in COPD group. About 50% of patients in both the groups had moderate obstruction by GOLD classification. The mean annual change of pre and post bronchodilator FEV1 in post-TB OAD were + 40.73ml/year and +48.52ml/year respectively while in COPD they were +87.09 ml/year and 108.28ml/year respectively. So it was observed that the mean incline in pre and post dilator FEV1 in post-TB OAD were almost half of that observed in COPD.
Conclusion: The annual change i.e the mean increase in pre and post bronchodilator FEV1 after optimization in post-TB OAD were significantly less than that in COPD.
References: 1. Baig IM, Saeed W, Khalil KF. J Coll Physicians Surg Pak. 2010 Aug;20(8).
- Copyright ©the authors 2016
