Abstract
Objective: To evaluate the clinical presentation and treatment outcomes in a retrospective& prospective study of extrapulmonary tuberculosis (EPTB) cases in Sohag Governorate.
Subjects and methods: 1611 cases of EPTB were included in the study. Data gathered included demographic data, site of disease, case category, treatment regimen, bacteriological, radiological, and histopathological status, and treatment outcome.
Results: There were 1611 patients for analysis. Approximately 51% of patients were aged between 20-39 years, and 35.8 % were male. 510 cases (31.7%%) lived in urban areas and 1101 (68.3%), in rural areas. New patients comprised 93.5% of cases. The most common form of EPTB was observed to be lymph node tuberculosis (39%);followed by pleural tuberculosis (22%), skeletal (19%), genitourinary (6.5%), and CNS (2.5%). EPTB was significantly higher in female compared with male (p<0.001). Among EPTB patients, treatment Completion was 77.7%%; remaining outcomes were 18.9% default, 0.7% failure, 1.4% death, 0.9 relapse and 0.7% transfer. Rate of defaulted from treatment was significantly higher in female compared with male,& in rural compared with urban areas (24.2%,vs 9.5% & 23.6%vs 8.8%, respectively, p<0.03). The proportion of completed treatment differ significantly between the urban & rural patients (87.1%, versus 73.4%, p<0.001).
Conclusion: We conclude that EPTB is very common in early adulthood, female & rural areas in Sohag Governorate, where social conditions are poor. Lymph nodes the most common localization. Defaulted treatment was significantly higher in female patients & rural areas.The significant number of defaulted patients demands that measures be adapted for the treatment of these patients.
- Copyright ©the authors 2016
