Skip to main content

Main menu

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • COVID-19 submission information
    • Peer reviewer login
  • Alerts
  • Podcasts
  • Subscriptions
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

User menu

  • Log in
  • Subscribe
  • Contact Us
  • My Cart

Search

  • Advanced search
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

Login

European Respiratory Society

Advanced Search

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • COVID-19 submission information
    • Peer reviewer login
  • Alerts
  • Podcasts
  • Subscriptions

H1N1pdm09 is an independent risk factor for severe influenza

Ana Lucía Figueredo Cacacho, Elisa Minchole, Dinora Polanco, Carolina Panadero, Laura Royo, José Javier Vengoechea, Francisco De Pablo, Salvador Bello Dronda
European Respiratory Journal 2016 48: PA2598; DOI: 10.1183/13993003.congress-2016.PA2598
Ana Lucía Figueredo Cacacho
1Respiratory, Hospital Universitario Miguel Servet, Zaragoza, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Elisa Minchole
1Respiratory, Hospital Universitario Miguel Servet, Zaragoza, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Dinora Polanco
1Respiratory, Hospital Universitario Miguel Servet, Zaragoza, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Carolina Panadero
1Respiratory, Hospital Universitario Miguel Servet, Zaragoza, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Laura Royo
1Respiratory, Hospital Universitario Miguel Servet, Zaragoza, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
José Javier Vengoechea
1Respiratory, Hospital Universitario Miguel Servet, Zaragoza, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Francisco De Pablo
1Respiratory, Hospital Universitario Miguel Servet, Zaragoza, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Salvador Bello Dronda
1Respiratory, Hospital Universitario Miguel Servet, Zaragoza, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
Loading

Abstract

INTRODUCTION: Since 2009, influenza A H1N1pdm09 coexists with seasonal influenza (H3N2). The aim of this study was to describe the severity differences between both.

METHODS: A retrospective study from January to March 2014 in Hospital Miguel Servet, Zaragoza, Spain. We studied hospitalized adults with influenza A, and compared radiologic, clinical manifestations and outcomes. Multivariable analysis was performed for severity, defined as the presence of bilateral or multilobar pneumonia, septic shock, intensive care unit (ICU) admission, acute respiratory distress syndrome (ARDS) and intrahospitalary mortality.

RESULTS: Out of 234 patients, 146 had A-H1N1 and 88 A-H3N2, and everyone received Oseltamivir within 24 h from admittance. The median age was 64 years old in H1N1 and 77 in H3N2 (P<0.001). In H1N1 group, 45.2% presented pneumonia, 4.8% ARDS, 10.9% septic shock and 12.3% needed invasive ventilation vs H3N2 group (see Table 1). In our regression model, H1N1 influenza (OR: 2,525), no vaccination (OR: 3.086), and coinfection (viral and bacterial) (adjusted OR: 2.821) were independent risk factors for severe disease.

Figure
  • Download figure
  • Open in new tab
  • Download powerpoint

CONCLUSIONS: Patients infected with H1N1 Influenza A virus were younger and presented more severe disease than those with H3N2. H1N1 influenza A, lack of Influenza vaccination and coinfection were risk factors for increased seasonal influenza severity.

  • Pneumonia
  • Copyright ©the authors 2016
Previous
Back to top
Vol 48 Issue suppl 60 Table of Contents
  • Table of Contents
  • Index by author
Email

Thank you for your interest in spreading the word on European Respiratory Society .

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
H1N1pdm09 is an independent risk factor for severe influenza
(Your Name) has sent you a message from European Respiratory Society
(Your Name) thought you would like to see the European Respiratory Society web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
H1N1pdm09 is an independent risk factor for severe influenza
Ana Lucía Figueredo Cacacho, Elisa Minchole, Dinora Polanco, Carolina Panadero, Laura Royo, José Javier Vengoechea, Francisco De Pablo, Salvador Bello Dronda
European Respiratory Journal Sep 2016, 48 (suppl 60) PA2598; DOI: 10.1183/13993003.congress-2016.PA2598

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
H1N1pdm09 is an independent risk factor for severe influenza
Ana Lucía Figueredo Cacacho, Elisa Minchole, Dinora Polanco, Carolina Panadero, Laura Royo, José Javier Vengoechea, Francisco De Pablo, Salvador Bello Dronda
European Respiratory Journal Sep 2016, 48 (suppl 60) PA2598; DOI: 10.1183/13993003.congress-2016.PA2598
del.icio.us logo Digg logo Reddit logo Technorati logo Twitter logo CiteULike logo Connotea logo Facebook logo Google logo Mendeley logo

Jump To

  • Article
  • Figures & Data
  • Info & Metrics
  • Tweet Widget
  • Facebook Like
  • Google Plus One

More in this TOC Section

  • Attenuated lymphocyte immune response in mycobacterium avium complex-lung disease through over-expressed programmed death-1 receptor
  • Epidemiology and clinical features of nontuberculous mycobacterial lung disease in a subtropical region in Japan: Analysis with a 7-year data in two major hospitals
  • Evaluation of inhaled dry powder tobramycin free base in non-cystic fibrosis bronchiectasis patients
Show more 10.1 Respiratory Infections

Related Articles

Navigate

  • Home
  • Current issue
  • Archive

About the ERJ

  • Journal information
  • Editorial board
  • Reviewers
  • Press
  • Permissions and reprints
  • Advertising

The European Respiratory Society

  • Society home
  • myERS
  • Privacy policy
  • Accessibility

ERS publications

  • European Respiratory Journal
  • ERJ Open Research
  • European Respiratory Review
  • Breathe
  • ERS books online
  • ERS Bookshop

Help

  • Feedback

For authors

  • Instructions for authors
  • Publication ethics and malpractice
  • Submit a manuscript

For readers

  • Alerts
  • Subjects
  • Podcasts
  • RSS

Subscriptions

  • Accessing the ERS publications

Contact us

European Respiratory Society
442 Glossop Road
Sheffield S10 2PX
United Kingdom
Tel: +44 114 2672860
Email: journals@ersnet.org

ISSN

Print ISSN:  0903-1936
Online ISSN: 1399-3003

Copyright © 2022 by the European Respiratory Society