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LATE-BREAKING ABSTRACT: Randomised controlled trial of telemonitoring with addition of daily forced oscillation in older people with COPD and co-morbidity

Pasquale Pompilio, Paolo Zanaboni, Trine Bergmo, Tanja Grzetic Romcevic, Valentina Isetta, Christer Janson, Andrei Malinovschi, Dorijan Marusic, Jo Middlemass, Josep Montserrat, Giulia Munaro, Kaiu Prikk, Ruth Sepper, A. Niroshan Siriwardena, Peter Calverley, Raffaele Dellaca, Roberto Rosso, Paul Walker
European Respiratory Journal 2016 48: OA3519; DOI: 10.1183/13993003.congress-2016.OA3519
Pasquale Pompilio
2Reasearch and Development, RESTECH SRL, Milan, Italy
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Paolo Zanaboni
6Norwegian Centre for E-health and Research, University Hospital of Northern Norway, Tromso, Norway
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Trine Bergmo
6Norwegian Centre for E-health and Research, University Hospital of Northern Norway, Tromso, Norway
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Tanja Grzetic Romcevic
10Department of Medicine, Bolnisnica Sezana, Sezana, Slovenia
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Valentina Isetta
8Facultat de Medicina, University of Barcelona, Barcelona, Spain
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Christer Janson
5Department of Medical Sciences, Uppsala University, Uppsala, Sweden
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Andrei Malinovschi
5Department of Medical Sciences, Uppsala University, Uppsala, Sweden
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Dorijan Marusic
10Department of Medicine, Bolnisnica Sezana, Sezana, Slovenia
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Jo Middlemass
7School of Health and Social Care, University of Lincoln, Lincoln, United Kingdom
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Josep Montserrat
8Facultat de Medicina, University of Barcelona, Barcelona, Spain
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Giulia Munaro
4Research and Development, Elettronica Bio Medicale SRL, Vicenza, Italy
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Kaiu Prikk
9Kliinilise Meditsiini Instituut, Tallinna Tehnikaülikool, Tallinn, Estonia
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Ruth Sepper
9Kliinilise Meditsiini Instituut, Tallinna Tehnikaülikool, Tallinn, Estonia
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A. Niroshan Siriwardena
7School of Health and Social Care, University of Lincoln, Lincoln, United Kingdom
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Peter Calverley
1Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom
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Raffaele Dellaca
2Reasearch and Development, RESTECH SRL, Milan, Italy
3Dipartimento di Elettronica, Politecnico di Milano, Milan, Italy
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Roberto Rosso
4Research and Development, Elettronica Bio Medicale SRL, Vicenza, Italy
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Paul Walker
1Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom
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Abstract

Evidence of clinical benefit and cost-effectiveness from daily symptom and simple telemonitoring in COPD is unproven. The CHROMED study explored the effect of telemonitoring in older people with COPD and significant co-morbidity who performed daily forced oscillation measurements via RESMON PRO DIARY to identify early physiological change associated with an exacerbation

Six centres in 5 countries randomised 312 people to 9 months telemonitoring (154) or daily symptom questionnaires (158). Each day the monitored group recorded symptoms, pulse, BP, oxygen saturation and airway resistance and reactance. An alert was generated if results exceeded pre-determined parameters and the participant was contacted by their local clinical centre to consider additional treatment

Baseline characteristics were evenly matched: mean age 71 years, FEV1 1.3L (50% predicted) and SGRQ score 49. 61% of subjects had 2+ exacerbations and 42% had been hospitalised in the previous year

Time to first hospitalisation did not differ albeit the monitoring group had fewer hospitalisations (79 vs 103; p=ns) and days in hospital (329 vs. 650; p=ns). However, subjects hospitalized with an AE COPD in the previous year (n=128) had a lower hospitalisation rate (p<0.04). Quality of life (EQ-5D) and health status (CAT) did not differ between groups. Mean cost in the monitored group was marginally lower (€4,615 vs €4,831; p=ns)

Telemonitoring including daily forced oscillation impacted neither time to first hospitalisation nor health status. Reduction in hospitalisation rate in subjects with previous hospitalisation suggests these individuals may benefit from telemonitoring and earlier treatment.

  • E-health
  • COPD - exacerbations
  • Physiology
  • Copyright ©the authors 2016
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LATE-BREAKING ABSTRACT: Randomised controlled trial of telemonitoring with addition of daily forced oscillation in older people with COPD and co-morbidity
Pasquale Pompilio, Paolo Zanaboni, Trine Bergmo, Tanja Grzetic Romcevic, Valentina Isetta, Christer Janson, Andrei Malinovschi, Dorijan Marusic, Jo Middlemass, Josep Montserrat, Giulia Munaro, Kaiu Prikk, Ruth Sepper, A. Niroshan Siriwardena, Peter Calverley, Raffaele Dellaca, Roberto Rosso, Paul Walker
European Respiratory Journal Sep 2016, 48 (suppl 60) OA3519; DOI: 10.1183/13993003.congress-2016.OA3519

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LATE-BREAKING ABSTRACT: Randomised controlled trial of telemonitoring with addition of daily forced oscillation in older people with COPD and co-morbidity
Pasquale Pompilio, Paolo Zanaboni, Trine Bergmo, Tanja Grzetic Romcevic, Valentina Isetta, Christer Janson, Andrei Malinovschi, Dorijan Marusic, Jo Middlemass, Josep Montserrat, Giulia Munaro, Kaiu Prikk, Ruth Sepper, A. Niroshan Siriwardena, Peter Calverley, Raffaele Dellaca, Roberto Rosso, Paul Walker
European Respiratory Journal Sep 2016, 48 (suppl 60) OA3519; DOI: 10.1183/13993003.congress-2016.OA3519
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