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Global Lung Function Initiative reference equations better describe a middle-aged, healthy French population than the European Community for Steel and Coal values

Sébastien Hulo, Virginie de Broucker, Jonathan Giovannelli, Nathalie Cherot-Kornobis, Véronique Nève, Annie Sobaszek, Luc Dauchet, Jean-Louis Edmé
European Respiratory Journal 2016 48: 1779-1781; DOI: 10.1183/13993003.00606-2016
Sébastien Hulo
1EA 4483, IMPECS: IMPact de l’Environnement Chimique sur la Santé Humaine, University of Lille, CHU Lille, Lille, France
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  • For correspondence: sebastien.hulo@chru-lille.fr
Virginie de Broucker
1EA 4483, IMPECS: IMPact de l’Environnement Chimique sur la Santé Humaine, University of Lille, CHU Lille, Lille, France
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Jonathan Giovannelli
2U1167, RID-AGE: Facteurs de Risque et Déterminants Moléculaires des Maladies Liées au Vieillissement, Institut Pasteur de Lille, University of Lille, INSERM, CHU Lille, Lille, France
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  • ORCID record for Jonathan Giovannelli
Nathalie Cherot-Kornobis
1EA 4483, IMPECS: IMPact de l’Environnement Chimique sur la Santé Humaine, University of Lille, CHU Lille, Lille, France
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Véronique Nève
1EA 4483, IMPECS: IMPact de l’Environnement Chimique sur la Santé Humaine, University of Lille, CHU Lille, Lille, France
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Annie Sobaszek
1EA 4483, IMPECS: IMPact de l’Environnement Chimique sur la Santé Humaine, University of Lille, CHU Lille, Lille, France
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Luc Dauchet
2U1167, RID-AGE: Facteurs de Risque et Déterminants Moléculaires des Maladies Liées au Vieillissement, Institut Pasteur de Lille, University of Lille, INSERM, CHU Lille, Lille, France
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Jean-Louis Edmé
1EA 4483, IMPECS: IMPact de l’Environnement Chimique sur la Santé Humaine, University of Lille, CHU Lille, Lille, France
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Extract

Spirometry plays a pivotal role in the clinical evaluation and management of respiratory diseases. Pulmonary function varies with age, height, sex and ethnicity, and test results need to be compared with predicted values and lower limits of normal (LLN) and upper limits of normal (ULN), that are appropriate for the individual being tested [1]. The European Community for Steel and Coal (ECSC) first published reference spirometric values for healthy non-smokers in 1983 based on a collation of regression equations [2]. In 2012, the Global Lung Function Initiative (GLI) presented prediction equations derived from measured values of a large population [1]. These newer statistical procedures provided us for the first time with a single equation for ages from 3 years through to 95 years. Measured values are converted to z-scores which describe how many standard deviations a measured value differs from the predicted value and these are independent of sex, age and height.

Abstract

GLI reference equations better describe a middle-aged, healthy French population than the ECSC values http://ow.ly/xF773022Xhy

Footnotes

  • Editorial comment in: Eur Respir J 2016; 48: 1535–1537.

  • Conflict of interest: None declared.

  • Received March 24, 2016.
  • Accepted June 17, 2016.
  • Copyright ©ERS 2016
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Global Lung Function Initiative reference equations better describe a middle-aged, healthy French population than the European Community for Steel and Coal values
Sébastien Hulo, Virginie de Broucker, Jonathan Giovannelli, Nathalie Cherot-Kornobis, Véronique Nève, Annie Sobaszek, Luc Dauchet, Jean-Louis Edmé
European Respiratory Journal Dec 2016, 48 (6) 1779-1781; DOI: 10.1183/13993003.00606-2016

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Global Lung Function Initiative reference equations better describe a middle-aged, healthy French population than the European Community for Steel and Coal values
Sébastien Hulo, Virginie de Broucker, Jonathan Giovannelli, Nathalie Cherot-Kornobis, Véronique Nève, Annie Sobaszek, Luc Dauchet, Jean-Louis Edmé
European Respiratory Journal Dec 2016, 48 (6) 1779-1781; DOI: 10.1183/13993003.00606-2016
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