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Table of Contents

01 October 2016; volume 48, issue 4

Electronic Resources

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    ERJ October Podcast: blood eosinophil count as a biomarker in patients with airway disease
    European Respiratory Journal 48 (4) E70; DOI: 10.1183/13993003.20164804.E70 Published 30 September 2016
    • ERJ Podcast

Editorials

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    The ERS-endorsed official ATS/CDC/IDSA clinical practice guidelines on treatment of drug-susceptible tuberculosis
    Giovanni Sotgiu, Payam Nahid, Robert Loddenkemper, Ibrahim Abubakar, Marc Miravitlles, Giovanni Battista Migliori
    European Respiratory Journal 48 (4) 963-971; DOI: 10.1183/13993003.01356-2016 Published 30 September 2016
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    A new alphabet for COPD care
    Edward Kerwin
    European Respiratory Journal 48 (4) 972-975; DOI: 10.1183/13993003.01242-2016 Published 30 September 2016
    • Disclosures
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    What can we learn from blood granulocyte patterns in patients with asthma?
    Kirsty Hambleton, Ian D. Pavord
    European Respiratory Journal 48 (4) 976-978; DOI: 10.1183/13993003.01567-2016 Published 30 September 2016
    • Disclosures
    • ERJ Podcast
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    Interleukin-6 as a biomarker for asthma: hype or is there something else?
    Matthew E. Poynter, Charles G. Irvin
    European Respiratory Journal 48 (4) 979-981; DOI: 10.1183/13993003.01597-2016 Published 30 September 2016
    • Disclosures
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    Why should we care about upper airway inflammation in obstructive sleep apnoea?
    Malcolm Kohler
    European Respiratory Journal 48 (4) 982-983; DOI: 10.1183/13993003.01248-2016 Published 30 September 2016
    • Disclosures
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    Corticosteroids for community-acquired pneumonia: a critical view of the evidence
    James D. Chalmers
    European Respiratory Journal 48 (4) 984-986; DOI: 10.1183/13993003.01329-2016 Published 30 September 2016
    • Disclosures
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    Towards a molecular classification of pulmonary arterial hypertension
    Stefan Gräf, Nicholas W. Morrell
    European Respiratory Journal 48 (4) 987-989; DOI: 10.1183/13993003.01550-2016 Published 30 September 2016

In Memoriam

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    Prof. Almaz A. Aldashev (1953–2016)
    Martin R. Wilkins, Nicholas W. Morrell
    European Respiratory Journal 48 (4) 990-991; DOI: 10.1183/13993003.01316-2016 Published 30 September 2016

Task Force Report

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    Principles of practice parameters for the treatment of sleep disordered breathing in the elderly and frail elderly: the consensus of the International Geriatric Sleep Medicine Task Force
    Nikolaus C. Netzer (Chair), Sonia Ancoli-Israel (Co-chair), Donald L. Bliwise, Stephany Fulda, Christine Roffe, Fernanda Almeida, Hakki Onen, Fannie Onen, Friedhart Raschke, Miguel Angel Martinez Garcia, Helmut Frohnhofen
    European Respiratory Journal 48 (4) 992-1018; DOI: 10.1183/13993003.01975-2015 Published 30 September 2016
    • Disclosures

Original Articles

  • COPD

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      Efficacy of an mHealth intervention to stimulate physical activity in COPD patients after pulmonary rehabilitation
      Sigrid N.W. Vorrink, Helianthe S.M. Kort, Thierry Troosters, Pieter Zanen, Jan-Willem J. Lammers
      European Respiratory Journal 48 (4) 1019-1029; DOI: 10.1183/13993003.00083-2016 Published 30 September 2016
      • Disclosures
      • Supplementary material
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      Efficacy and safety of aclidinium/formoterol versus salmeterol/fluticasone: a phase 3 COPD study
      Claus Vogelmeier, Pier Luigi Paggiaro, Jordi Dorca, Pawel Sliwinski, Marcel Mallet, Anne-Marie Kirsten, Jutta Beier, Beatriz Seoane, Rosa Maria Segarra, Anne Leselbaum
      European Respiratory Journal 48 (4) 1030-1039; DOI: 10.1183/13993003.00216-2016 Published 30 September 2016
      • Disclosures
  • Asthma

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      Blood granulocyte patterns as predictors of asthma phenotypes in adults from the EGEA study
      Rachel Nadif, Valérie Siroux, Anne Boudier, Nicole le Moual, Jocelyne Just, Frederic Gormand, Christophe Pison, Regis Matran, Isabelle Pin
      European Respiratory Journal 48 (4) 1040-1051; DOI: 10.1183/13993003.00336-2016 Published 30 September 2016
      • Disclosures
      • Supplementary material
      • ERJ Podcast
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      Comorbidities and elevated IL-6 associate with negative outcome in adult-onset asthma
      Pinja Ilmarinen, Leena E. Tuomisto, Onni Niemelä, Joanna Danielsson, Jussi Haanpää, Terhi Kankaanranta, Hannu Kankaanranta
      European Respiratory Journal 48 (4) 1052-1062; DOI: 10.1183/13993003.02198-2015 Published 30 September 2016
      • Disclosures
      • Supplementary material
  • Paediatric pulmonology and asthma

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      Childhood obesity in relation to poor asthma control and exacerbation: a meta-analysis
      Fariba Ahmadizar, Susanne J.H. Vijverberg, Hubertus G.M. Arets, Anthonius de Boer, Jason E. Lang, Meyer Kattan, Colin N.A. Palmer, Somnath Mukhopadhyay, Steve Turner, Anke H. Maitland-van der Zee
      European Respiratory Journal 48 (4) 1063-1073; DOI: 10.1183/13993003.00766-2016 Published 30 September 2016
      • Disclosures
      • Supplementary material
  • Paediatric pulmonology

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      Feasibility of lung clearance index in a clinical setting in pre-school children
      Barrett Downing, Samantha Irving, Yvonne Bingham, Louise Fleming, Andrew Bush, Sejal Saglani
      European Respiratory Journal 48 (4) 1074-1080; DOI: 10.1183/13993003.00374-2016 Published 30 September 2016
      • Supplementary material
      • Disclosures
  • Primary ciliary dyskinesia

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      Clinical manifestations in primary ciliary dyskinesia: systematic review and meta-analysis
      Myrofora Goutaki, Anna Bettina Meier, Florian S. Halbeisen, Jane S. Lucas, Sharon D. Dell, Elisabeth Maurer, Carmen Casaulta, Maja Jurca, Ben D. Spycher, Claudia E. Kuehni
      European Respiratory Journal 48 (4) 1081-1095; DOI: 10.1183/13993003.00736-2016 Published 30 September 2016
      • Supplementary material
    • Open Access
      Diagnosing primary ciliary dyskinesia: an international patient perspective
      Laura Behan, Audrey Dunn Galvin, Bruna Rubbo, Sarah Masefield, Fiona Copeland, Michele Manion, Bernhard Rindlisbacher, Beatrice Redfern, Jane S. Lucas
      European Respiratory Journal 48 (4) 1096-1107; DOI: 10.1183/13993003.02018-2015 Published 30 September 2016
      • Supplementary material
      • Disclosures
  • Sleep

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      Upper airway and systemic inflammation in obstructive sleep apnoea
      Eugenio Vicente, Jose M. Marin, Santiago J. Carrizo, Carlos S. Osuna, Ricardo González, Marta Marin-Oto, Marta Forner, Paul Vicente, Pablo Cubero, Ana V. Gil, Xavier Soler
      European Respiratory Journal 48 (4) 1108-1117; DOI: 10.1183/13993003.00234-2016 Published 30 September 2016
      • Supplementary material
  • Pulmonary vascular diseases and genetics

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      Genetic analyses in a cohort of children with pulmonary hypertension
      Marilyne Levy, Mélanie Eyries, Isabelle Szezepanski, Magalie Ladouceur, Sophie Nadaud, Damien Bonnet, Florent Soubrier
      European Respiratory Journal 48 (4) 1118-1126; DOI: 10.1183/13993003.00211-2016 Published 30 September 2016
      • Disclosures
      • Supplementary material
  • Pulmonary vascular diseases

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      Docosahexaenoic acid causes rapid pulmonary arterial relaxation via KCa channel-mediated hyperpolarisation in pulmonary hypertension
      Chandran Nagaraj, Bi Tang, Bence M. Nagy, Rita Papp, Pritesh P. Jain, Leigh M. Marsh, Andrea L. Meredith, Bahil Ghanim, Walter Klepetko, Grazyna Kwapiszewska, E. Kenneth Weir, Horst Olschewski, Andrea Olschewski
      European Respiratory Journal 48 (4) 1127-1136; DOI: 10.1183/13993003.01814-2015 Published 30 September 2016
      • Disclosures
      • Supplementary material
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      Notch1 signalling regulates endothelial proliferation and apoptosis in pulmonary arterial hypertension
      Swati Dabral, Xia Tian, Baktybek Kojonazarov, Rajkumar Savai, Hossein Ardeschir Ghofrani, Norbert Weissmann, Monica Florio, Jan Sun, Danny Jonigk, Lavinia Maegel, Friedrich Grimminger, Werner Seeger, Soni Savai Pullamsetti, Ralph Theo Schermuly
      European Respiratory Journal 48 (4) 1137-1149; DOI: 10.1183/13993003.00773-2015 Published 30 September 2016
      • Supplementary material
  • Respiratory infections

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      Pathogen- and antibiotic-specific effects of prednisone in community-acquired pneumonia
      Sebastian A. Wirz, Claudine A. Blum, Philipp Schuetz, Werner C. Albrich, Christoph Noppen, Beat Mueller, Mirjam Christ-Crain, Philip E. Tarr  for the STEP Study Group
      European Respiratory Journal 48 (4) 1150-1159; DOI: 10.1183/13993003.00474-2016 Published 30 September 2016
      • Supplementary material
      • Disclosures
  • Tuberculosis

    • Open Access
      Multidrug-resistant tuberculosis treatment failure detection depends on monitoring interval and microbiological method
      Carole D. Mitnick, Richard A. White, Chunling Lu, Carly A. Rodriguez, Jaime Bayona, Mercedes C. Becerra, Marcos Burgos, Rosella Centis, Theodore Cohen, Helen Cox, Lia D'Ambrosio, Manfred Danilovitz, Dennis Falzon, Irina Y. Gelmanova, Maria T. Gler, Jennifer A. Grinsdale, Timothy H. Holtz, Salmaan Keshavjee, Vaira Leimane, Dick Menzies, Giovanni Battista Migliori, Meredith B. Milstein, Sergey P. Mishustin, Marcello Pagano, Maria I. Quelapio, Karen Shean, Sonya S. Shin, Arielle W. Tolman, Martha L. van der Walt, Armand Van Deun, Piret Viiklepp  on behalf of the Collaborative Group for Analysis of Bacteriology Data in MDR-TB Treatment
      European Respiratory Journal 48 (4) 1160-1170; DOI: 10.1183/13993003.00462-2016 Published 30 September 2016
      • Disclosures
      • Supplementary material
  • Interstitial lung diseases

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      Peripheral blood myeloid-derived suppressor cells reflect disease status in idiopathic pulmonary fibrosis
      Isis E. Fernandez, Flavia R. Greiffo, Marion Frankenberger, Julia Bandres, Katharina Heinzelmann, Claus Neurohr, Rudolf Hatz, Dominik Hartl, Jürgen Behr, Oliver Eickelberg
      European Respiratory Journal 48 (4) 1171-1183; DOI: 10.1183/13993003.01826-2015 Published 30 September 2016
      • Supplementary material
      • Disclosures
  • Lung cancer

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      Polymorphisms in cancer-related pathway genes and lung cancer
      Shin Yup Lee, Hyo-Gyoung Kang, Jin Eun Choi, Deuk Kju Jung, Won Kee Lee, Hyun Chul Lee, So Yeon Lee, Seung Soo Yoo, Jaehee Lee, Yangki Seok, Eung Bae Lee, Seung Ick Cha, Sukki Cho, Chang Ho Kim, Myung Hoon Lee, Jae Yong Park
      European Respiratory Journal 48 (4) 1184-1191; DOI: 10.1183/13993003.02040-2015 Published 30 September 2016
      • Supplementary material
  • Dyspnoea

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      Continuous laryngoscopy quantitates laryngeal behaviour in exercise and recovery
      J. Tod Olin, Matthew S. Clary, Elizabeth M. Fan, Kristina L. Johnston, Claire M. State, Matthew Strand, Kent L. Christopher
      European Respiratory Journal 48 (4) 1192-1200; DOI: 10.1183/13993003.00160-2016 Published 30 September 2016
      • Supplementary material
      • Disclosures

Back to Basics

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    Control of lung defence by mucins and macrophages: ancient defence mechanisms with modern functions
    William J. Janssen, Adrianne L. Stefanski, Bruce S. Bochner, Christopher M. Evans
    European Respiratory Journal 48 (4) 1201-1214; DOI: 10.1183/13993003.00120-2015 Published 30 September 2016
    • Disclosures

Agora

  • Research letters

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      Age-dependent elastin degradation is enhanced in chronic obstructive pulmonary disease
      Jeffrey T.J. Huang, Charlotte E. Bolton, Bruce E. Miller, Ruth Tal-Singer, Roberto A. Rabinovich, Colin N.A. Palmer, Neil C. Thomson, William MacNee the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators
      European Respiratory Journal 48 (4) 1215-1218; DOI: 10.1183/13993003.01125-2016 Published 30 September 2016
      • Disclosures
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      The effect of hypoxia and re-oxygenation on adipose tissue lipolysis in COPD patients
      Andrea Plihalova, Hana Bartakova, Martina Vasakova, Sumeet Gulati, Isabelle deGlisezinski, Vladimir Stich, Jan Polak
      European Respiratory Journal 48 (4) 1218-1220; DOI: 10.1183/13993003.00602-2016 Published 30 September 2016
      • Disclosures
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      Air pollution exposure is associated with restrictive ventilatory patterns
      Kim de Jong, Judith M. Vonk, Wilma L. Zijlema, Ronald P. Stolk, Diana A. van der Plaat, Gerard Hoek, Bert Brunekreef, Dirkje S. Postma, H. Marike Boezen on behalf of the LifeLines Cohort Study Group
      European Respiratory Journal 48 (4) 1221-1224; DOI: 10.1183/13993003.00556-2016 Published 30 September 2016
      • Disclosures
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      Near infrared spectroscopy for the assessment of peripheral tissue oxygenation in pulmonary arterial hypertension
      Marios Panagiotou, Ioannis Vogiatzis, Zafeiris Louvaris, Geeshath Jayasekera, Alison MacKenzie, Neil Mcglinchey, Julien S. Baker, Alistair C. Church, Andrew J. Peacock, Martin K. Johnson
      European Respiratory Journal 48 (4) 1224-1227; DOI: 10.1183/13993003.01022-2016 Published 30 September 2016
      • Disclosures
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      High burden of prevalent tuberculosis among previously treated people in Southern Africa suggests potential for targeted control interventions
      Florian M. Marx, Sian Floyd, Helen Ayles, Peter Godfrey-Faussett, Nulda Beyers, Ted Cohen
      European Respiratory Journal 48 (4) 1227-1230; DOI: 10.1183/13993003.00716-2016 Published 30 September 2016
      • Disclosures
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      Fixed-dose combination and therapeutic drug monitoring in tuberculosis: friend or foe?
      Marlanka A. Zuur, Onno W. Akkerman, Lina Davies Forsman, Yi Hu, Rongdong Zheng, Judith Bruchfeld, Simon Tiberi, Giovanni Battista Migliori, Jan-Willem C. Alffenaar
      European Respiratory Journal 48 (4) 1230-1233; DOI: 10.1183/13993003.00833-2016 Published 30 September 2016
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      Tuberculosis in London: the convergence of clinical and social complexity
      Charlotte Anderson, Sarah R. Anderson, Helen Maguire, Andrew C. Hayward, Alistair Story
      European Respiratory Journal 48 (4) 1233-1236; DOI: 10.1183/13993003.00749-2016 Published 30 September 2016
      • Supplementary material
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      Dosage of isoniazid and rifampicin poorly predicts drug exposure in tuberculosis patients
      Marieke G.G. Sturkenboom, Onno W. Akkerman, Richard van Altena, Wiel C.M. de Lange, Jos G.W. Kosterink, Tjip S. van der Werf, Jan-Willem C. Alffenaar
      European Respiratory Journal 48 (4) 1237-1239; DOI: 10.1183/13993003.00986-2016 Published 30 September 2016
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      Eosinophilic pneumonia associated with pirfenidone therapy
      Diana C. Gomez, Borna Mehrad
      European Respiratory Journal 48 (4) 1240-1242; DOI: 10.1183/13993003.00809-2016 Published 30 September 2016
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      Can intermediate monocytes predict response to infliximab therapy in sarcoidosis?
      Daniëlle Hijdra, Adriane D.M. Vorselaars, Heleen A. Crommelin, Coline H.M. van Moorsel, Bob Meek, Anke M.E. Claessen, Ger T. Rijkers, Jan C. Grutters
      European Respiratory Journal 48 (4) 1242-1245; DOI: 10.1183/13993003.00709-2016 Published 30 September 2016
  • Correspondence

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      Asthma and risk of bronchiectasis exacerbation: we still need more evidence
      Yong-hua Gao, Wei-jie Guan, Rong-chang Chen, Guo-jun Zhang
      European Respiratory Journal 48 (4) 1246-1247; DOI: 10.1183/13993003.00780-2016 Published 30 September 2016
    • You have accessRestricted access
      Asthma and risk of bronchiectasis exacerbation: we still need more evidence
      Bei Mao, Jia-Wei Yang, Hai-Wen Lu, Jin-Fu Xu
      European Respiratory Journal 48 (4) 1247-1248; DOI: 10.1183/13993003.00979-2016 Published 30 September 2016
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      Obstructive sleep apnoea and bone health
      Jia-Yu Zhong, Ling-Qing Yuan
      European Respiratory Journal 48 (4) 1248-1249; DOI: 10.1183/13993003.00870-2016 Published 30 September 2016
      • Disclosures
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      Obstructive sleep apnoea and bone health
      Claudio Liguori, Eleonora Piccirilli, Francesca Izzi, Nicola Biagio Mercuri, Umberto Tarantino, Fabio Placidi
      European Respiratory Journal 48 (4) 1249-1250; DOI: 10.1183/13993003.01219-2016 Published 30 September 2016
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      Pulmonary mucosa-associated lymphoid tissue lymphoma revisited
      Emilie Catherinot, Elisabeth Longchampt, Agnès Ferroni, Elisabeth Rivaud, Pierre Cahen, Louis-Jean Couderc
      European Respiratory Journal 48 (4) 1250-1251; DOI: 10.1183/13993003.00901-2016 Published 30 September 2016
    • You have accessRestricted access
      Pulmonary mucosa-associated lymphoid tissue lymphoma revisited
      Raphael Borie, Marie Wislez, Martine Antoine, Christiane Copie-Bergman, Catherine Thieblemont, Jacques Cadranel
      European Respiratory Journal 48 (4) 1252; DOI: 10.1183/13993003.01143-2016 Published 30 September 2016
      • Disclosures
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      Tuberculosis screening yield of asylum seekers in Europe
      Wouter Arrazola de Oñate, Lilas Weber, Kristien Janssens, Maryse Wanlin, Annemie Forier, Sandrina Schol, Kathia van Egmond
      European Respiratory Journal 48 (4) 1253-1254; DOI: 10.1183/13993003.00991-2016 Published 30 September 2016
    • You have accessRestricted access
      Tuberculosis screening yield of asylum seekers in Europe
      Gerard de Vries, Job van Rest, Wieneke Meijer, Henrieke Schimmel, Bert Wolters, Rob van Hest, Michael Kimerling
      European Respiratory Journal 48 (4) 1255-1256; DOI: 10.1183/13993003.01617-2016 Published 30 September 2016
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      Comprehensive cost of treating one patient with MDR/pre-XDR-TB in Wellington, New Zealand
      Amanda McNaughton, Timothy Blackmore, Harry McNaughton
      European Respiratory Journal 48 (4) 1256-1259; DOI: 10.1183/13993003.00876-2016 Published 30 September 2016
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European Respiratory Journal: 48 (4)
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