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Table of Contents

01 August 2016; volume 48, issue 2

Electronic Resources

  • You have accessRestricted access
    ERJ August Podcast: management of chronic thromboembolic pulmonary hypertension
    European Respiratory Journal 48 (2) E68; DOI: 10.1183/13993003.20164802.E68 Published 31 July 2016
    • ERJ Podcast

Editorials

  • You have accessRestricted access
    Which CD8+ T-cells in asthma? Attacking or defending?
    Simonetta Baraldo, Graziella Turato, Manuel G. Cosio, Marina Saetta
    European Respiratory Journal 48 (2) 287-290; DOI: 10.1183/13993003.01037-2016 Published 31 July 2016
    • Disclosures
  • You have accessRestricted access
    Metabolic consequences of obesity as an “outside in” mechanism of disease severity in asthma
    Michael C. Peters, John V. Fahy
    European Respiratory Journal 48 (2) 291-293; DOI: 10.1183/13993003.01132-2016 Published 31 July 2016
    • Disclosures
  • You have accessRestricted access
    Complex lung function in severe asthma: seeing is believing
    Gregory G. King, Cindy Thamrin
    European Respiratory Journal 48 (2) 294-296; DOI: 10.1183/13993003.01120-2016 Published 31 July 2016
    • Disclosures
  • You have accessRestricted access
    Primary ciliary dyskinesia: the patients grow up
    Claudia E. Kuehni, Myrofora Goutaki, Mary Carroll, Jane S. Lucas
    European Respiratory Journal 48 (2) 297-300; DOI: 10.1183/13993003.01098-2016 Published 31 July 2016
    • Disclosures
  • You have accessRestricted access
    Interleukin-1α: a key player for epithelial-to-mesenchymal signalling in COPD?
    Antoine Froidure, Maha Zohra Ladjemi, Charles Pilette
    European Respiratory Journal 48 (2) 301-304; DOI: 10.1183/13993003.01180-2016 Published 31 July 2016
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    Pulmonary arterial hypertension and the Enigma code of smouldering inflammation
    Jose Gomez-Arroyo, Antonio Abbate, Norbert F. Voelkel
    European Respiratory Journal 48 (2) 305-307; DOI: 10.1183/13993003.00996-2016 Published 31 July 2016
    • Disclosures
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    The difficult diagnosis of pulmonary vascular disease in heart failure
    Robert Naeije, Anna Ryan Hemnes
    European Respiratory Journal 48 (2) 308-310; DOI: 10.1183/13993003.00789-2016 Published 31 July 2016
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    The difficult diagnosis of pulmonary vascular disease in heart failure
    Nazzareno Galiè, Alessandra Manes, Massimiliano Palazzini
    European Respiratory Journal 48 (2) 311-314; DOI: 10.1183/13993003.00854-2016 Published 31 July 2016
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    Should we use gait speed in COPD, FEV1 in frailty and dyspnoea in both?
    Jean Bousquet, Anh Tuan Dinh-Xuan, Thomas Similowski, João Malva, Joël Ankri, Mario Barbagallo, Leonardo Fabbri, Marc Humbert, Jacques Mercier, Carlos Robalo-Cordeiro, Leocadio Rodriguez-Manas, Bruno Vellas
    European Respiratory Journal 48 (2) 315-319; DOI: 10.1183/13993003.00633-2016 Published 31 July 2016
    • Disclosures

Study Protocol

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    A phase III randomised controlled trial of single-dose triple therapy in COPD: the IMPACT protocol
    Steven J. Pascoe, David A. Lipson, Nicholas Locantore, Helen Barnacle, Noushin Brealey, Rajat Mohindra, Mark T. Dransfield, Ian Pavord, Neil Barnes
    European Respiratory Journal 48 (2) 320-330; DOI: 10.1183/13993003.02165-2015 Published 31 July 2016
    • Supplementary material
    • Disclosures

Original Articles

  • Occupational lung disease

    • Open Access
      Thoracic dust exposure is associated with lung function decline in cement production workers
      Karl-Christian Nordby, Hilde Notø, Wijnand Eduard, Marit Skogstad, Anne Kristin Fell, Yngvar Thomassen, Øivind Skare, Antonio Bergamaschi, Antonio Pietroiusti, Rolf Abderhalden, Johny Kongerud, Helge Kjuus
      European Respiratory Journal 48 (2) 331-339; DOI: 10.1183/13993003.02061-2015 Published 31 July 2016
      • Disclosures
      • Supplementary material
  • COPD

    • You have accessRestricted access
      Physical activity and exercise capacity in patients with moderate COPD exacerbations
      Ayedh D. Alahmari, Beverly S. Kowlessar, Anant R.C. Patel, Alex J. Mackay, James P. Allinson, Jadwiga A. Wedzicha, Gavin C. Donaldson
      European Respiratory Journal 48 (2) 340-349; DOI: 10.1183/13993003.01105-2015 Published 31 July 2016
      • Disclosures
      • Supplementary material
    • You have accessRestricted access
      Accelerated telomere attrition in children and teenagers with α1-antitrypsin deficiency
      Amparo Escribano, Sara Pastor, Ana Reula, Silvia Castillo, Silvia Vicente, Francisco Sanz, Francisco Casas, María Torres, Estrella Fernández-Fabrellas, Pilar Codoñer-Franch, Francisco Dasí
      European Respiratory Journal 48 (2) 350-358; DOI: 10.1183/13993003.00176-2016 Published 31 July 2016
      • Supplementary material
    • You have accessRestricted access
      Interleukin-1α drives the dysfunctional cross-talk of the airway epithelium and lung fibroblasts in COPD
      Emmanuel T. Osei, Jacobien A. Noordhoek, Tillie L. Hackett, Anita I.R. Spanjer, Dirkje S. Postma, Wim Timens, Corry-Anke Brandsma, Irene H. Heijink
      European Respiratory Journal 48 (2) 359-369; DOI: 10.1183/13993003.01911-2015 Published 31 July 2016
      • Disclosures
      • Supplementary material
  • Asthma

    • You have accessRestricted access
      Is ventilation heterogeneity related to asthma control?
      Sarah Svenningsen, Parameswaran Nair, Fumin Guo, David G. McCormack, Grace Parraga
      European Respiratory Journal 48 (2) 370-379; DOI: 10.1183/13993003.00393-2016 Published 31 July 2016
      • Supplementary material
    • You have accessRestricted access
      Neuro-immune interactions in chemical-induced airway hyperreactivity
      Fien C. Devos, Brett Boonen, Yeranddy A. Alpizar, Tania Maes, Valérie Hox, Sven Seys, Lore Pollaris, Adrian Liston, Benoit Nemery, Karel Talavera, Peter H.M. Hoet, Jeroen A.J. Vanoirbeek
      European Respiratory Journal 48 (2) 380-392; DOI: 10.1183/13993003.01778-2015 Published 31 July 2016
      • Supplementary material
    • You have accessRestricted access
      Lung function decline in asthma patients with elevated bronchial CD8, CD4 and CD3 cells
      Irene den Otter, Luuk N.A. Willems, Annemarie van Schadewijk, Simone van Wijngaarden, Kirsten Janssen, Ronald C. de Jeu, Jacob K. Sont, Peter J. Sterk, Pieter S. Hiemstra
      European Respiratory Journal 48 (2) 393-402; DOI: 10.1183/13993003.01525-2015 Published 31 July 2016
      • Disclosures
      • Supplementary material
    • You have accessRestricted access
      Insulin resistance modifies the association between obesity and current asthma in adults
      Juan Carlos Cardet, Samuel Ash, Tope Kusa, Carlos A. Camargo Jr, Elliot Israel
      European Respiratory Journal 48 (2) 403-410; DOI: 10.1183/13993003.00246-2016 Published 31 July 2016
      • Supplementary material
  • Paediatric pulmonology and lung function

    • You have accessRestricted access
      Natural variability of lung function in young healthy school children
      Jane Kirkby, Vassiliki Bountziouka, Sooky Lum, Angie Wade, Janet Stocks
      European Respiratory Journal 48 (2) 411-419; DOI: 10.1183/13993003.01795-2015 Published 31 July 2016
    • You have accessRestricted access
      Utility of measuring FEV0.75/FVC ratio in preschoolers with uncontrolled wheezing disorder
      Véronique Nève, Sébastien Hulo, Jean-Louis Edmé, Sophie Boileau, Georges Baquet, Guillaume Pouessel, Caroline Thumerelle, Antoine Deschildre, Régis Matran
      European Respiratory Journal 48 (2) 420-427; DOI: 10.1183/13993003.01391-2015 Published 31 July 2016
      • Supplementary material
  • Paediatric pulmonology

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      Physical activity is not associated with spirometric indices in lung-healthy German youth
      Maia P. Smith, Andrea von Berg, Dietrich Berdel, Carl-Peter Bauer, Barbara Hoffmann, Sibylle Koletzko, Dennis Nowak, Joachim Heinrich, Holger Schulz
      European Respiratory Journal 48 (2) 428-440; DOI: 10.1183/13993003.01408-2015 Published 31 July 2016
      • Supplementary material
  • Primary ciliary dyskinesia

    • You have accessRestricted access
      A longitudinal study characterising a large adult primary ciliary dyskinesia population
      Anand Shah, Amelia Shoemark, Stephanie J. MacNeill, Basrull Bhaludin, Andrew Rogers, Diana Bilton, David M. Hansell, Robert Wilson, Michael R. Loebinger
      European Respiratory Journal 48 (2) 441-450; DOI: 10.1183/13993003.00209-2016 Published 31 July 2016
      • Supplementary material
  • Cystic fibrosis

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      Optimal correction of distinct CFTR folding mutants in rectal cystic fibrosis organoids
      Johanna F. Dekkers, Ricardo A. Gogorza Gondra, Evelien Kruisselbrink, Annelotte M. Vonk, Hettie M. Janssens, Karin M. de Winter-de Groot, Cornelis K. van der Ent, Jeffrey M. Beekman
      European Respiratory Journal 48 (2) 451-458; DOI: 10.1183/13993003.01192-2015 Published 31 July 2016
      • Disclosures
  • Pulmonary vascular diseases

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      CD133+ cells in pulmonary arterial hypertension
      Vasile Foris, Gabor Kovacs, Leigh M. Marsh, Zoltán Bálint, Martin Tötsch, Alexander Avian, Philipp Douschan, Bahil Ghanim, Walter Klepetko, Andrea Olschewski, Horst Olschewski
      European Respiratory Journal 48 (2) 459-469; DOI: 10.1183/13993003.01523-2015 Published 31 July 2016
      • Supplementary material
      • Disclosures
    • You have accessRestricted access
      Role of interleukin-1 receptor 1/MyD88 signalling in the development and progression of pulmonary hypertension
      Aurélien Parpaleix, Valérie Amsellem, Amal Houssaini, Shariq Abid, Marielle Breau, Elisabeth Marcos, Daigo Sawaki, Marion Delcroix, Rozenn Quarck, Aurélie Maillard, Isabelle Couillin, Bernhard Ryffel, Serge Adnot
      European Respiratory Journal 48 (2) 470-483; DOI: 10.1183/13993003.01448-2015 Published 31 July 2016
      • Supplementary material
  • Sarcoidosis

    • You have accessRestricted access
      Expanded lung T-bet+RORγT+ CD4+ T-cells in sarcoidosis patients with a favourable disease phenotype
      Ylva Kaiser, Rico Lepzien, Susanna Kullberg, Anders Eklund, Anna Smed-Sörensen, Johan Grunewald
      European Respiratory Journal 48 (2) 484-494; DOI: 10.1183/13993003.00092-2016 Published 31 July 2016
      • Supplementary material
  • Lung cancer

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      Risk factors for short-term outcomes after thoracoscopic lobectomy for lung cancer
      Masataka Irie, Ryoichi Nakanishi, Manabu Yasuda, Yoshihisa Fujino, Kazumi Hamada, Masahiro Hyodo
      European Respiratory Journal 48 (2) 495-503; DOI: 10.1183/13993003.01939-2015 Published 31 July 2016
  • Mechanisms of lung disease

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      Cigarette smoke-induced epithelial expression of WNT-5B: implications for COPD
      Irene H. Heijink, Harold G. de Bruin, Robin Dennebos, Marnix R. Jonker, Jacobien A. Noordhoek, Corry-Anke Brandsma, Maarten van den Berge, Dirkje S. Postma
      European Respiratory Journal 48 (2) 504-515; DOI: 10.1183/13993003.01541-2015 Published 31 July 2016
      • Supplementary material
      • Disclosures

Reviews

  • Open Access
    Development, roll-out and impact of Xpert MTB/RIF for tuberculosis: what lessons have we learnt and how can we do better?
    Heidi Albert, Ruvandhi R. Nathavitharana, Chris Isaacs, Madhukar Pai, Claudia M. Denkinger, Catharina C. Boehme
    European Respiratory Journal 48 (2) 516-525; DOI: 10.1183/13993003.00543-2016 Published 31 July 2016
    • Disclosures
  • Open Access
    Quality of life in patients with chronic thromboembolic pulmonary hypertension
    Stephen C. Mathai, Hossein-Ardeschir Ghofrani, Eckhard Mayer, Joanna Pepke-Zaba, Sylvia Nikkho, Gérald Simonneau
    European Respiratory Journal 48 (2) 526-537; DOI: 10.1183/13993003.01626-2015 Published 31 July 2016
    • Disclosures
    • ERJ Podcast

Back To Basics

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    Age-driven developmental drift in the pathogenesis of idiopathic pulmonary fibrosis
    Moisés Selman, Carlos López-Otín, Annie Pardo
    European Respiratory Journal 48 (2) 538-552; DOI: 10.1183/13993003.00398-2016 Published 31 July 2016

Agora

  • Research letters

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      How to define pulmonary hypertension due to left heart disease
      Mario Gerges, Christian Gerges, Irene M. Lang
      European Respiratory Journal 48 (2) 553-555; DOI: 10.1183/13993003.00432-2016 Published 31 July 2016
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      A retrospective cohort study of patients with pulmonary embolism: the impact of comorbidities on patient's outcome
      Antonella Mameli, Maria Antonietta Palmas, Antonello Antonelli, Paolo Contu, Paolo Prandoni, Francesco Marongiu
      European Respiratory Journal 48 (2) 555-557; DOI: 10.1183/13993003.02193-2015 Published 31 July 2016
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      Cessation of long-acting β2-agonist in children with persistent asthma on inhaled corticosteroids
      Francine M. Ducharme, Roxanne Gagnon, Brigitte Bénard, Sze Man Tse, Robert Thivierge
      European Respiratory Journal 48 (2) 558-560; DOI: 10.1183/13993003.00014-2016 Published 31 July 2016
      • Disclosures
    • You have accessRestricted access
      Factors associated with undiagnosed and overdiagnosed COPD
      Andrea S. Gershon, Jeremiah Hwee, Kenneth R. Chapman, Shawn D. Aaron, Denis E. O'Donnell, Matthew B. Stanbrook, Jean Bourbeau, Wan Tan, Jiandong Su, J. Charles Victor, Teresa To
      European Respiratory Journal 48 (2) 561-564; DOI: 10.1183/13993003.00458-2016 Published 31 July 2016
      • Disclosures
    • You have accessRestricted access
      Handling missing items in the Exacerbations of Chronic Pulmonary Disease Tool
      Andrew W. Hitchings, Emma H. Baker, Paul W. Jones
      European Respiratory Journal 48 (2) 564-566; DOI: 10.1183/13993003.00269-2016 Published 31 July 2016
      • Disclosures
    • You have accessRestricted access
      Interval training induces clinically meaningful effects in daily activity levels in COPD
      Zafeiris Louvaris, Stavroula Spetsioti, Eleni A. Kortianou, Maroula Vasilopoulou, Ioannis Nasis, Georgios Kaltsakas, Nikolaos G. Koulouris, Ioannis Vogiatzis
      European Respiratory Journal 48 (2) 567-570; DOI: 10.1183/13993003.00679-2016 Published 31 July 2016
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      Silent aspiration in patients with exacerbation of COPD
      Zeguang Zheng, Zhida Wu, Ni Liu, Ping Chen, Peng Hou, Xinni Wang, Yimin Fu, Weijian Liang, Rongchang Chen
      European Respiratory Journal 48 (2) 570-573; DOI: 10.1183/13993003.00007-2016 Published 31 July 2016
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      Susceptibility genes for lung diseases in the major histocompatibility complex revealed by lung expression quantitative trait loci analysis
      Maxime Lamontagne, Philippe Joubert, Wim Timens, Dirkje S. Postma, Ke Hao, David Nickle, Don D. Sin, Peter D. Pare, Michel Laviolette, Yohan Bossé
      European Respiratory Journal 48 (2) 573-576; DOI: 10.1183/13993003.00114-2016 Published 31 July 2016
      • Disclosures
    • You have accessRestricted access
      Hydrogen cyanide emission in the lung by Staphylococcus aureus
      Anne H. Neerincx, Ylona A.M. Linders, Laura Vermeulen, Robert A. Belderbos, Julien Mandon, Esther van Mastrigt, Marielle W. Pijnenburg, Jakko van Ingen, Johan W. Mouton, Leo A.J. Kluijtmans, Ron A. Wevers, Frans J.M. Harren, Simona M. Cristescu, Peter J.F.M. Merkus
      European Respiratory Journal 48 (2) 577-579; DOI: 10.1183/13993003.02093-2015 Published 31 July 2016
    • You have accessRestricted access
      Pouched rats as detectors of tuberculosis: comparison to concentrated smear microscopy
      Timothy L. Edwards, Emilio Valverde, Christiaan Mulder, Christophe Cox, Alan Poling
      European Respiratory Journal 48 (2) 579-582; DOI: 10.1183/13993003.00264-2016 Published 31 July 2016
      • Disclosures
    • You have accessRestricted access
      Is bedaquiline as effective as fluoroquinolones in the treatment of multidrug-resistant tuberculosis?
      Lorenzo Guglielmetti, Damien Le Dû, Nicolas Veziris, Eric Caumes, Dhiba Marigot-Outtandy, Yazdan Yazdanpanah, Jérôme Robert, Mathilde Fréchet-Jachym for the MDR-TB Management Group of the French National Reference Center for Mycobacteria and the Physicians of the French MDR-TB Cohort
      European Respiratory Journal 48 (2) 582-585; DOI: 10.1183/13993003.00411-2016 Published 31 July 2016
      • Disclosures
    • Open Access
      Respiratory decline is integral to disease progression in Huntington's disease
      Una Jones, Monica Busse, Stephanie Enright, Anne E. Rosser
      European Respiratory Journal 48 (2) 585-588; DOI: 10.1183/13993003.02215-2015 Published 31 July 2016
      • Disclosures
  • Correspondence

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      Increased use of high-flow nasal oxygen during bronchoscopy
      Pedro Silva Santos, Cristiana Cruz, Antonio M. Esquinas
      European Respiratory Journal 48 (2) 589; DOI: 10.1183/13993003.00441-2016 Published 31 July 2016
    • You have accessRestricted access
      Increased use of high-flow nasal oxygen during bronchoscopy
      Beatrice La Combe, Jonathan Messika, Muriel Fartoukh, Jean-Damien Ricard
      European Respiratory Journal 48 (2) 590-592; DOI: 10.1183/13993003.00565-2016 Published 31 July 2016
      • Disclosures

Author Correction

  • You have accessRestricted access
    “Cortical drive to breathe in amyotrophic lateral sclerosis: a dyspnoea-worsening defence?” Marjolaine Georges, Elise Morawiec, Mathieu Raux, Jésus Gonzalez-Bermejo, Pierre-François Pradat, Thomas Similowski and Capucine Morélot-Panzini. Eur Respir J 2016; 47: 1818–1828.
    European Respiratory Journal 48 (2) 593; DOI: 10.1183/13993003.51686-2015 Published 31 July 2016

Erratum

  • You have accessRestricted access
    “Unfavourable effects of medically indicated oral anticoagulants on survival in idiopathic pulmonary fibrosis.” Michael Kreuter, Marlies S. Wijsenbeek, Martina Vasakova, Paolo Spagnolo, Martin Kolb, Ulrich Costabel, Derek Weycker, Klaus-Uwe Kirchgaessler and Toby M. Maher. Eur Respir J 2016; 47: 1776–1784.
    European Respiratory Journal 48 (2) 593; DOI: 10.1183/13993003.52087-2015 Published 31 July 2016
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European Respiratory Journal: 48 (2)
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