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Table of Contents

01 June 2016; volume 47, issue 6

Electronic resources

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    ERJ June Podcast: unfavourable effects of oral anticoagulants on survival in idiopathic pulmonary fibrosis
    European Respiratory Journal 47 (6) E66; DOI: 10.1183/13993003.20164706.E66 Published 31 May 2016
    • ERJ Podcast

Editorials

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    Bronchiectasthma and asthmectasis!
    Joan B. Soriano, José Serrano
    European Respiratory Journal 47 (6) 1597-1600; DOI: 10.1183/13993003.00289-2016 Published 31 May 2016
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    Adding biological markers to COPD categorisation schemes: a way towards more personalised care?
    Nicolas Roche
    European Respiratory Journal 47 (6) 1601-1605; DOI: 10.1183/13993003.00401-2016 Published 31 May 2016
    • Disclosures
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    COPD treatment: about collateral channels and collapsing airways
    Ralf-Harto Hubner, Dominik Herzog
    European Respiratory Journal 47 (6) 1606-1610; DOI: 10.1183/13993003.00343-2016 Published 31 May 2016
    • Disclosures
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    When insulin has to work hard to keep the sugar at bay the upper airway collapses away
    Danny J. Eckert, Arie Oliven
    European Respiratory Journal 47 (6) 1611-1614; DOI: 10.1183/13993003.00590-2016 Published 31 May 2016
    • Disclosures
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    Sildenafil for pulmonary hypertension complicating idiopathic pulmonary fibrosis: a rationale grounded in basic science
    Paul M. Hassoun, Steven D. Nathan
    European Respiratory Journal 47 (6) 1615-1617; DOI: 10.1183/13993003.00395-2016 Published 31 May 2016
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    How to follow-up patients with hereditary haemorrhagic telangiectasia and suspected pulmonary arteriovenous malformations
    Thierry Chinet
    European Respiratory Journal 47 (6) 1618-1621; DOI: 10.1183/13993003.00340-2016 Published 31 May 2016
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    Interstitial pneumonitis with autoimmune features (IPAF): a work in progress
    Fabrizio Luppi, Athol U. Wells
    European Respiratory Journal 47 (6) 1622-1624; DOI: 10.1183/13993003.00690-2016 Published 31 May 2016
    • Disclosures
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    Beryllium disease and sarcoidosis: still besties after all these years?
    Daniel A. Culver
    European Respiratory Journal 47 (6) 1625-1628; DOI: 10.1183/13993003.00805-2016 Published 31 May 2016
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    Genetic studies yield clues to the pathogenesis of Langerhans cell histiocytosis
    Li Zhang, Joel Moss
    European Respiratory Journal 47 (6) 1629-1631; DOI: 10.1183/13993003.00568-2016 Published 31 May 2016
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    A wider pathological network underlying breathlessness and respiratory failure in amyotrophic lateral sclerosis
    Kyle T.S. Pattinson, Martin R. Turner
    European Respiratory Journal 47 (6) 1632-1634; DOI: 10.1183/13993003.00321-2016 Published 31 May 2016

Original Articles

  • COPD

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      Prognostic assessment in COPD without lung function: the B-AE-D indices
      Lucas Boeck, Joan B. Soriano, Marjolein Brusse-Keizer, Francesco Blasi, Konstantinos Kostikas, Wim Boersma, Branislava Milenkovic, Renaud Louis, Alicia Lacoma, Remco Djamin, Joachim Aerts, Antoni Torres, Gernot Rohde, Tobias Welte, Pablo Martinez-Camblor, Janko Rakic, Andreas Scherr, Michael Koller, Job van der Palen, Jose M. Marin, Inmaculada Alfageme, Pere Almagro, Ciro Casanova, Cristobal Esteban, Juan J. Soler-Cataluña, Juan P. de-Torres, Marc Miravitlles, Bartolome R. Celli, Michael Tamm, Daiana Stolz
      European Respiratory Journal 47 (6) 1635-1644; DOI: 10.1183/13993003.01485-2015 Published 31 May 2016
      • Supplementary material
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      Linoleic acid-derived lipid mediators increase in a female-dominated subphenotype of COPD
      David Balgoma, Mingxing Yang, Marcus Sjödin, Stuart Snowden, Reza Karimi, Bettina Levänen, Heta Merikallio, Riitta Kaarteenaho, Lena Palmberg, Kjell Larsson, David J. Erle, Sven-Erik Dahlén, Barbro Dahlén, C. Magnus Sköld, Åsa M. Wheelock, Craig E. Wheelock
      European Respiratory Journal 47 (6) 1645-1656; DOI: 10.1183/13993003.01080-2015 Published 31 May 2016
      • Disclosures
      • Supplementary material
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      Collapse phenomenon during Chartis collateral ventilation assessment
      Wolfgang Gesierich, Konstantinos Samitas, Frank Reichenberger, Juergen Behr
      European Respiratory Journal 47 (6) 1657-1667; DOI: 10.1183/13993003.01973-2015 Published 31 May 2016
      • Supplementary material
      • Disclosures
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      Real-life assessment of the multidimensional nature of dyspnoea in COPD outpatients
      Capucine Morélot-Panzini, Hélène Gilet, Bernard Aguilaniu, Philippe Devillier, Alain Didier, Thierry Perez, Christophe Pignier, Benoit Arnould, Thomas Similowski
      European Respiratory Journal 47 (6) 1668-1679; DOI: 10.1183/13993003.01998-2015 Published 31 May 2016
      • Supplementary material
      • Disclosures
  • Asthma and bronchiectasis

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      Asthma and bronchiectasis exacerbation
      Bei Mao, Jia-Wei Yang, Hai-Wen Lu, Jin-Fu Xu
      European Respiratory Journal 47 (6) 1680-1686; DOI: 10.1183/13993003.01862-2015 Published 31 May 2016
  • Paediatric pulmonology

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      Tidal flow variability measured by impedance pneumography relates to childhood asthma risk
      Ville-Pekka Seppä, Anna S. Pelkonen, Anne Kotaniemi-Syrjänen, Jari Viik, Mika J. Mäkelä, L. Pekka Malmberg
      European Respiratory Journal 47 (6) 1687-1696; DOI: 10.1183/13993003.00989-2015 Published 31 May 2016
      • Disclosures
      • Supplementary material
  • Cystic fibrosis

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      Forecasting US ivacaftor outcomes and cost in cystic fibrosis patients with the G551D mutation
      Piyameth Dilokthornsakul, Ryan N. Hansen, Jonathan D. Campbell
      European Respiratory Journal 47 (6) 1697-1705; DOI: 10.1183/13993003.01444-2015 Published 31 May 2016
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      Multicentre chest computed tomography standardisation in children and adolescents with cystic fibrosis: the way forward
      Wieying Kuo, Mariette P.C. Kemner-van de Corput, Adria Perez-Rovira, Marleen de Bruijne, Isabelle Fajac, Harm A.W.M. Tiddens, Marcel van Straten  on behalf of the ECFS-CTN/SCIFI CF study group
      European Respiratory Journal 47 (6) 1706-1717; DOI: 10.1183/13993003.01601-2015 Published 31 May 2016
      • Disclosures
      • Supplementary material
  • Sleep

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      Pharyngeal collapsibility during sleep is elevated in insulin-resistant females with morbid obesity
      Oscar L. Llanos, Panagis Galiatsatos, Edmarie Guzmán-Vélez, Susheel P. Patil, Philip L. Smith, Thomas Magnuson, Michael Schweitzer, Kimberley Steele, Vsevolod Y. Polotsky, Alan R. Schwartz
      European Respiratory Journal 47 (6) 1718-1726; DOI: 10.1183/13993003.00918-2015 Published 31 May 2016
  • Pulmonary vascular diseases

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      Initial dual oral combination therapy in pulmonary arterial hypertension
      Olivier Sitbon, Caroline Sattler, Laurent Bertoletti, Laurent Savale, Vincent Cottin, Xavier Jaïs, Pascal De Groote, Ari Chaouat, Céline Chabannes, Emmanuel Bergot, Hélène Bouvaist, Claire Dauphin, Arnaud Bourdin, Fabrice Bauer, David Montani, Marc Humbert, Gérald Simonneau
      European Respiratory Journal 47 (6) 1727-1736; DOI: 10.1183/13993003.02043-2015 Published 31 May 2016
      • Disclosures
      • Disclosures
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      Vascular effects of sildenafil in patients with pulmonary fibrosis and pulmonary hypertension: an ex vivo/in vitro study
      Javier Milara, Juan Escrivá, José Luis Ortiz, Gustavo Juan, Enrique Artigues, Esteban Morcillo, Julio Cortijo
      European Respiratory Journal 47 (6) 1737-1749; DOI: 10.1183/13993003.01259-2015 Published 31 May 2016
      • Disclosures
      • Supplementary material
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      Follow-up of pulmonary right-to-left shunt in hereditary haemorrhagic telangiectasia
      Veronique M.M. Vorselaars, Sebastiaan Velthuis, Repke J. Snijder, Cornelis J.J. Westermann, Jan A. Vos, Johannes J. Mager, Martijn C. Post
      European Respiratory Journal 47 (6) 1750-1757; DOI: 10.1183/13993003.01588-2015 Published 31 May 2016
  • Tuberculosis

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      Comparison of effectiveness and safety of imipenem/clavulanate- versus meropenem/clavulanate-containing regimens in the treatment of MDR- and XDR-TB
      Simon Tiberi, Giovanni Sotgiu, Lia D'Ambrosio, Rosella Centis, Marcos Abdo Arbex, Edith Alarcon Arrascue, Jan Willem Alffenaar, Jose A. Caminero, Mina Gaga, Gina Gualano, Alena Skrahina, Ivan Solovic, Giorgia Sulis, Marina Tadolini, Valentina Alarcon Guizado, Saverio De Lorenzo, Aurora Jazmín Roby Arias, Anna Scardigli, Onno W. Akkerman, Alena Aleksa, Janina Artsukevich, Vera Auchynka, Eduardo Henrique Bonini, Félix Antonio Chong Marín, Lorena Collahuazo López, Gerard de Vries, Simone Dore, Heinke Kunst, Alberto Matteelli, Charalampos Moschos, Fabrizio Palmieri, Apostolos Papavasileiou, Marie-Christine Payen, Andrea Piana, Antonio Spanevello, Dante Vargas Vasquez, Pietro Viggiani, Veronica White, Alimuddin Zumla, Giovanni Battista Migliori
      European Respiratory Journal 47 (6) 1758-1766; DOI: 10.1183/13993003.00214-2016 Published 31 May 2016
  • Interstitial lung diseases

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      Characterisation of patients with interstitial pneumonia with autoimmune features
      Justin M. Oldham, Ayodeji Adegunsoye, Eleanor Valenzi, Cathryn Lee, Leah Witt, Lena Chen, Aliya N. Husain, Steven Montner, Jonathan H. Chung, Vincent Cottin, Aryeh Fischer, Imre Noth, Rekha Vij, Mary E. Strek
      European Respiratory Journal 47 (6) 1767-1775; DOI: 10.1183/13993003.01565-2015 Published 31 May 2016
      • Disclosures
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      Unfavourable effects of medically indicated oral anticoagulants on survival in idiopathic pulmonary fibrosis
      Michael Kreuter, Marlies S. Wijsenbeek, Martina Vasakova, Paolo Spagnolo, Martin Kolb, Ulrich Costabel, Derek Weycker, Klaus-Uwe Kirchgaessler, Toby M. Maher
      European Respiratory Journal 47 (6) 1776-1784; DOI: 10.1183/13993003.02087-2015 Published 31 May 2016
      • Disclosures
      • Supplementary material
      • ERJ Podcast
  • Orphan lung disease

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      Recurrent NRAS mutations in pulmonary Langerhans cell histiocytosis
      Samia Mourah, Alexandre How-Kit, Véronique Meignin, Dominique Gossot, Gwenaël Lorillon, Emmanuelle Bugnet, Florence Mauger, Celeste Lebbe, Sylvie Chevret, Jörg Tost, Abdellatif Tazi
      European Respiratory Journal 47 (6) 1785-1796; DOI: 10.1183/13993003.01677-2015 Published 31 May 2016
      • Supplementary material
      • Disclosures
  • Beryllium-induced lung disease

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      Beryllium-induced lung disease exhibits expression profiles similar to sarcoidosis
      Li Li, Lori J. Silveira, Nabeel Hamzeh, May Gillespie, Peggy M. Mroz, Annyce S. Mayer, Tasha E. Fingerlin, Lisa A. Maier
      European Respiratory Journal 47 (6) 1797-1808; DOI: 10.1183/13993003.01469-2015 Published 31 May 2016
      • Disclosures
      • Supplementary material
  • Lung cancer

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      In-hospital mortality following lung cancer resection: nationwide administrative database
      Pierre-Benoit Pagès, Jonathan Cottenet, Anne-Sophie Mariet, Alain Bernard, Catherine Quantin
      European Respiratory Journal 47 (6) 1809-1817; DOI: 10.1183/13993003.00052-2016 Published 31 May 2016
  • Dyspnoea and amyotrophic lateral sclerosis

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      Cortical drive to breathe in amyotrophic lateral sclerosis: a dyspnoea-worsening defence?
      Marjolaine Georges, Elise Morawiec, Mathieu Raux, Jésus Gonzalez-Bermejo, Pierre-François Pradat, Thomas Similowski, Capucine Morélot-Panzini
      European Respiratory Journal 47 (6) 1818-1828; DOI: 10.1183/13993003.01686-2015 Published 31 May 2016

Review

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    Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia syndrome
    Giulio Rossi, Alberto Cavazza, Paolo Spagnolo, Nicola Sverzellati, Lucia Longo, Agita Jukna, Gloria Montanari, Cristiano Carbonelli, Giada Vincenzi, Giuseppe Bogina, Renato Franco, Marcello Tiseo, Vincent Cottin, Thomas V. Colby
    European Respiratory Journal 47 (6) 1829-1841; DOI: 10.1183/13993003.01954-2015 Published 31 May 2016

Back to Basics

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    “Scar-cinoma”: viewing the fibrotic lung mesenchymal cell in the context of cancer biology
    Jeffrey C. Horowitz, John J. Osterholzer, Antonia Marazioti, Georgios T. Stathopoulos
    European Respiratory Journal 47 (6) 1842-1854; DOI: 10.1183/13993003.01201-2015 Published 31 May 2016

Agora

  • Research letters

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      Airflow obstruction is associated with increased smooth muscle extracellular matrix
      Robyn L. Jones, Peter B. Noble, John G. Elliot, Howard W. Mitchell, Peter K. McFawn, James C. Hogg, Alan L. James
      European Respiratory Journal 47 (6) 1855-1857; DOI: 10.1183/13993003.01709-2015 Published 31 May 2016
      • Disclosures
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      An outreaching model of tertiary difficult asthma care reduces adverse asthma outcomes and healthcare utilisation costs
      Veeresh K. Patil, Christine Townshend, Frances Mitchell, Ramesh J. Kurukulaaratchy
      European Respiratory Journal 47 (6) 1857-1860; DOI: 10.1183/13993003.01689-2015 Published 31 May 2016
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      Use of the modified Borg scale and numerical rating scale to measure chronic breathlessness: a pooled data analysis
      Miriam J. Johnson, Lucy Close, Suzie C. Gillon, Alex Molassiotis, Paul H. Lee, Morag C. Farquhar on behalf of the Breathlessness Research Interest Group (BRIG)
      European Respiratory Journal 47 (6) 1861-1864; DOI: 10.1183/13993003.02089-2015 Published 31 May 2016
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      Asthmatics with high levels of serum surfactant protein D have more severe disease
      Alida Benfante, Salvatore Battaglia, Stefania Principe, Chiara Di Mitri, Alessandra Paternò, Mario Spatafora, Nicola Scichilone
      European Respiratory Journal 47 (6) 1864-1867; DOI: 10.1183/13993003.02142-2015 Published 31 May 2016
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      Incorporating therapeutic drug monitoring into the World Health Organization hierarchy of tuberculosis diagnostics
      Samiksha Ghimire, Mathieu S. Bolhuis, Marieke G.G. Sturkenboom, Onno W. Akkerman, Wiel C.M. de Lange, Tjip S. van der Werf, Jan-Willem C. Alffenaar
      European Respiratory Journal 47 (6) 1867-1869; DOI: 10.1183/13993003.00040-2016 Published 31 May 2016
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      Low yield of screening asylum seekers from countries with a tuberculosis incidence of <50 per 100 000 population
      Gerard de Vries, Job van Rest, Wieneke Meijer, Bert Wolters, Rob van Hest
      European Respiratory Journal 47 (6) 1870-1872; DOI: 10.1183/13993003.00099-2016 Published 31 May 2016
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      A 380-gene meta-signature of active tuberculosis compared with healthy controls
      Simon Blankley, Christine M. Graham, Joe Levin, Jacob Turner, Matthew P.R. Berry, Chloe I. Bloom, Zhaohui Xu, Virgina Pascual, Jacques Banchereau, Damien Chaussabel, Ronan Breen, George Santis, Derek M. Blankenship, Marc Lipman, Anne O'Garra
      European Respiratory Journal 47 (6) 1873-1876; DOI: 10.1183/13993003.02121-2015 Published 31 May 2016
      • Disclosures
    • Open Access
      Implementation of digital technology solutions for a lung health trial in rural Malawi
      Blessings Chisunkha, Hastings Banda, Rachael Thomson, S. Bertel Squire, Kevin Mortimer
      European Respiratory Journal 47 (6) 1876-1879; DOI: 10.1183/13993003.00045-2016 Published 31 May 2016
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      Somatic DICER1 mutations in adult-onset pulmonary blastoma
      Leanne de Kock, Ismaël Bah, Joan Brunet, Harriet Druker, Itziar Astigarraga, Joaquim Bosch-Barrera, Dorothée Bouron-Dal Soglio, Van-Hung Nguyen, David Malkin, John R. Priest, William D. Foulkes
      European Respiratory Journal 47 (6) 1879-1882; DOI: 10.1183/13993003.00172-2016 Published 31 May 2016
      • Disclosures
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      Should lymphangioleiomyomatosis patients be permitted to donate blood?
      Anne F. Eder, Jay H. Ryu, Joel Moss
      European Respiratory Journal 47 (6) 1883-1884; DOI: 10.1183/13993003.00410-2016 Published 31 May 2016
  • Correspondence

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      Risk of COPD in smokers with low transfer factor
      Martin R. Miller, Vito Brusasco
      European Respiratory Journal 47 (6) 1885-1886; DOI: 10.1183/13993003.02218-2015 Published 31 May 2016
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      The birth of a new lung syndrome?
      Philip H. Quanjer
      European Respiratory Journal 47 (6) 1886-1888; DOI: 10.1183/13993003.00155-2016 Published 31 May 2016
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      Progression to COPD in smokers with normal spirometry/low DLCO using different methods to determine normal levels
      Ben-Gary Harvey, Yael Strulovici-Barel, Robert J. Kaner, Abraham Sanders, Thomas L. Vincent, Jason G. Mezey, Ronald G. Crystal
      European Respiratory Journal 47 (6) 1888-1889; DOI: 10.1183/13993003.00435-2016 Published 31 May 2016
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      Sensitivity to chemotherapy/tyrosine kinase inhibitors of mucinous lepidic adenocarcinoma should be tested in a phase III trial?
      Jacques Cadranel, Marie Wislez, Alexandra Langlais, Franck Morin, Gérard Zalcman
      European Respiratory Journal 47 (6) 1890-1891; DOI: 10.1183/13993003.01936-2015 Published 31 May 2016
      • Disclosures

Author Corrections

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    “Blood basophil activation is a reliable biomarker of allergic bronchopulmonary aspergillosis in cystic fibrosis.” Yael Gernez, Jeffrey Waters, Bojana Mirković, Gillian M. Lavelle, Colleen E. Dunn, Zoe A. Davies, Cassie Everson, Rabindra Tirouvanziam, Elana Silver, Sylvan Wallenstein, Sanjay H. Chotirmall, Noel G. McElvaney, Leonore A. Herzenberg and Richard B. Moss. Eur Respir J 2016; 47: 177–185.
    European Respiratory Journal 47 (6) 1892; DOI: 10.1183/13993003.51068-2015 Published 31 May 2016
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    “Asthma inhaler adherence determinants in adults: systematic review of observational data.” Alexandra L. Dima, Gimena Hernandez, Oriol Cunillera, Montserrat Ferrer, Marijn de Bruin and the ASTRO-LAB group. Eur Respir J 2015; 45: 994–1018.
    European Respiratory Journal 47 (6) 1892; DOI: 10.1183/09031936.50172114 Published 31 May 2016
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European Respiratory Journal: 47 (6)
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