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Table of Contents

01 April 2016; volume 47, issue 4

Electronic resources

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    ERJ April Podcast: a new diagnostic tool for primary ciliary dyskinesia
    European Respiratory Journal 47 (4) E64; DOI: 10.1183/13993003.20164704.E64 Published 1 April 2016
    • ERJ Podcast

Editorials

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    The ERS Research Agency: the beginning
    Joan B. Soriano, James Paton, Fernando Martin Burrieza, Werner Bill, Carine Pannetier, Stefano Aliberti, Ian M. Adcock, Scott Wagers, Giovanni Battista Migliori
    European Respiratory Journal 47 (4) 1017-1023; DOI: 10.1183/13993003.02109-2015 Published 1 April 2016
    • Disclosures
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    A new perspective on COPD exacerbations: monitoring impact by measuring physical, psychological and social resilience
    Martijn A. Spruit, Frits M.E. Franssen, Erica P.A. Rutten, Suzan Wopereis, Emiel F.M. Wouters, Lowie E.G.W. Vanfleteren
    European Respiratory Journal 47 (4) 1024-1027; DOI: 10.1183/13993003.01645-2015 Published 1 April 2016
    • Disclosures
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    AIRWAYS-ICPs (European Innovation Partnership on Active and Healthy Ageing) from concept to implementation
    Jean Bousquet, Cristina Barbara, Eric Bateman, Elisabeth Bel, Mike Bewick, Niels H. Chavannes, Alvaro A. Cruz, Tari Haahtela, Peter W. Hellings, Nikolai Khaltaev, Karin Lodrup Carlsen, Antonella Muraro, Carlos Robalo Cordeiro, Jose Rosado-Pinto, Boleslaw Samolinski, Timo Strandberg, Arunas Valiulis, Arzu Yorgancioglu, Torsten Zuberbier the AIRWAYS-ICPs working group
    European Respiratory Journal 47 (4) 1028-1033; DOI: 10.1183/13993003.01856-2015 Published 1 April 2016
    • Disclosures
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    The lung microbiome: the perfect culprit for COPD exacerbations?
    Carine Gomez, Pascal Chanez
    European Respiratory Journal 47 (4) 1034-1036; DOI: 10.1183/13993003.00270-2016 Published 1 April 2016
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    Phenotyping bronchiectasis: is it all about sputum and infection?
    Daniel J. Smith
    European Respiratory Journal 47 (4) 1037-1039; DOI: 10.1183/13993003.00163-2016 Published 1 April 2016
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    Mast cells in asthma: biomarker and therapeutic target
    Laurent L. Reber, John V. Fahy
    European Respiratory Journal 47 (4) 1040-1042; DOI: 10.1183/13993003.00065-2016 Published 1 April 2016
    • Disclosures
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    Asthma management in primary care: caring, sharing and working together
    Sinthia Z. Bosnic-Anticevich
    European Respiratory Journal 47 (4) 1043-1046; DOI: 10.1183/13993003.00240-2016 Published 1 April 2016
    • Disclosures
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    Deriving information from external Big Databases and Big Data analytics: all that glitters is not gold
    Miguel Angel Martinez-Garcia, Anh Tuan Dinh-Xuan
    European Respiratory Journal 47 (4) 1047-1049; DOI: 10.1183/13993003.00060-2016 Published 1 April 2016
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    The puzzle of metabolic effects of obstructive sleep apnoea in children
    Oreste Marrone, Maria R. Bonsignore
    European Respiratory Journal 47 (4) 1050-1053; DOI: 10.1183/13993003.00115-2016 Published 1 April 2016
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    Have we found how to identify candidates for thrombolysis among normotensive patients with acute pulmonary embolism?
    Piotr Pruszczyk
    European Respiratory Journal 47 (4) 1054-1056; DOI: 10.1183/13993003.02007-2015 Published 1 April 2016
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    Idiopathic pulmonary fibrosis: securing a confident diagnosis for every patient
    Mark G. Jones, Simon L.F. Walsh, Kirk D. Jones, Luca Richeldi
    European Respiratory Journal 47 (4) 1057-1059; DOI: 10.1183/13993003.00265-2016 Published 1 April 2016
    • Disclosures
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    Reducing antibiotics use for ventilator-associated pneumonia in brain-injured patients
    Miquel Ferrer, Antoni Torres
    European Respiratory Journal 47 (4) 1060-1061; DOI: 10.1183/13993003.02190-2015 Published 1 April 2016

Original articles

  • Air pollution and asthma

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      Perinatal air pollution exposure and development of asthma from birth to age 10 years
      Hind Sbihi, Lillian Tamburic, Mieke Koehoorn, Michael Brauer
      European Respiratory Journal 47 (4) 1062-1071; DOI: 10.1183/13993003.00746-2015 Published 1 April 2016
      • Disclosures
      • Supplementary material
  • Bronchial hyperresponsiveness and smoking

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      Interaction between the DNAH9 gene and early smoke exposure in bronchial hyperresponsiveness
      Marie-Hélène Dizier, Rachel Nadif, Patricia Margaritte-Jeannin, Sheila J. Barton, Chloé Sarnowski, Valérie Gagné-Ouellet, Myriam Brossard, Nolwenn Lavielle, Jocelyne Just, Mark Lathrop, John W. Holloway, Catherine Laprise, Emmanuelle Bouzigon, Florence Demenais
      European Respiratory Journal 47 (4) 1072-1081; DOI: 10.1183/13993003.00849-2015 Published 1 April 2016
  • COPD

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      Lung microbiome dynamics in COPD exacerbations
      Zhang Wang, Mona Bafadhel, Koirobi Haldar, Aaron Spivak, David Mayhew, Bruce E. Miller, Ruth Tal-Singer, Sebastian L. Johnston, Mohammadali Yavari Ramsheh, Michael R. Barer, Christopher E. Brightling, James R. Brown
      European Respiratory Journal 47 (4) 1082-1092; DOI: 10.1183/13993003.01406-2015 Published 1 April 2016
      • Disclosures
      • Supplementary material
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      Enhanced monocyte migration to CXCR3 and CCR5 chemokines in COPD
      Claudia Costa, Suzanne L. Traves, Susan J. Tudhope, Peter S. Fenwick, Kylie B.R. Belchamber, Richard E.K. Russell, Peter J. Barnes, Louise E. Donnelly
      European Respiratory Journal 47 (4) 1093-1102; DOI: 10.1183/13993003.01642-2015 Published 1 April 2016
      • Disclosures
      • Supplementary material
  • Primary ciliary dyskinesia

    • Open Access
      PICADAR: a diagnostic predictive tool for primary ciliary dyskinesia
      Laura Behan, Borislav D. Dimitrov, Claudia E. Kuehni, Claire Hogg, Mary Carroll, Hazel J. Evans, Myrofora Goutaki, Amanda Harris, Samantha Packham, Woolf T. Walker, Jane S. Lucas
      European Respiratory Journal 47 (4) 1103-1112; DOI: 10.1183/13993003.01551-2015 Published 1 April 2016
      • Supplementary material
      • ERJ Podcast
  • Bronchiectasis

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      Clinical phenotypes in adult patients with bronchiectasis
      Stefano Aliberti, Sara Lonni, Simone Dore, Melissa J. McDonnell, Pieter C. Goeminne, Katerina Dimakou, Thomas C. Fardon, Robert Rutherford, Alberto Pesci, Marcos I. Restrepo, Giovanni Sotgiu, James D. Chalmers
      European Respiratory Journal 47 (4) 1113-1122; DOI: 10.1183/13993003.01899-2015 Published 1 April 2016
      • Supplementary material
      • Disclosures
  • Asthma

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      Sputum mast cell subtypes relate to eosinophilia and corticosteroid response in asthma
      Gang Wang, Katherine J. Baines, Juan Juan Fu, Lisa G. Wood, Jodie L. Simpson, Vanessa M. McDonald, Douglas C. Cowan, D. Robin Taylor, Jan O. Cowan, Peter G. Gibson
      European Respiratory Journal 47 (4) 1123-1133; DOI: 10.1183/13993003.01098-2015 Published 1 April 2016
      • Disclosures
      • Supplementary material
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      Pharmacists' interventions on clinical asthma outcomes: a systematic review
      Victoria Garcia-Cardenas, Carol Armour, Shalom I. Benrimoj, Fernando Martinez-Martinez, Inajara Rotta, Fernando Fernandez-Llimos
      European Respiratory Journal 47 (4) 1134-1143; DOI: 10.1183/13993003.01497-2015 Published 1 April 2016
      • Supplementary material
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      Fertility outcomes in asthma: a clinical study of 245 women with unexplained infertility
      Elisabeth Juul Gade, Simon Francis Thomsen, Svend Lindenberg, Vibeke Backer
      European Respiratory Journal 47 (4) 1144-1151; DOI: 10.1183/13993003.01389-2015 Published 1 April 2016
      • Supplementary material
  • Sleep and paediatric pulmonology

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      Impact of obstructive sleep apnoea on insulin resistance in nonobese and obese children
      Dorit Koren, David Gozal, Mona F. Philby, Rakesh Bhattacharjee, Leila Kheirandish-Gozal
      European Respiratory Journal 47 (4) 1152-1161; DOI: 10.1183/13993003.01430-2015 Published 1 April 2016
      • Supplementary material
  • Sleep

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      The effect of sex and age on the comorbidity burden of OSA: an observational analysis from a large nationwide US health claims database
      Babak Mokhlesi, Sandra A. Ham, David Gozal
      European Respiratory Journal 47 (4) 1162-1169; DOI: 10.1183/13993003.01618-2015 Published 1 April 2016
      • Disclosures
      • Supplementary material
  • Pulmonary vascular diseases

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      Comparison of risk assessment strategies for not-high-risk pulmonary embolism
      Lukas Hobohm, Kristian Hellenkamp, Gerd Hasenfuß, Thomas Münzel, Stavros Konstantinides, Mareike Lankeit
      European Respiratory Journal 47 (4) 1170-1178; DOI: 10.1183/13993003.01605-2015 Published 1 April 2016
      • Supplementary material
      • Disclosures
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      Age-related upper limits of normal for maximum upright exercise pulmonary haemodynamics
      Rudolf K.F. Oliveira, Manyoo Agarwal, Julie A. Tracy, Abbey L. Karin, Alexander R. Opotowsky, Aaron B. Waxman, David M. Systrom
      European Respiratory Journal 47 (4) 1179-1188; DOI: 10.1183/13993003.01307-2015 Published 1 April 2016
      • Supplementary material
  • Interstitial lung diseases

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      Radiologic–pathologic discordance in biopsy-proven usual interstitial pneumonia
      Kunihiro Yagihashi, Jason Huckleberry, Thomas V. Colby, Henry D. Tazelaar, Jordan Zach, Baskaran Sundaram, Sudhakar Pipavath, Marvin I. Schwarz, David A. Lynch for the Idiopathic Pulmonary Fibrosis Clinical Research Network (IPFnet)
      European Respiratory Journal 47 (4) 1189-1197; DOI: 10.1183/13993003.01680-2015 Published 1 April 2016
      • Supplementary material
      • Disclosures
  • Sarcoidosis

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      99mTc-anti-TNF-α antibody for the imaging of disease activity in pulmonary sarcoidosis
      Roeland Vis, Gaurav Malviya, Alberto Signore, Jan C. Grutters, Bob Meek, Ewoudt M.W. van de Garde, Ruth G.M. Keijsers
      European Respiratory Journal 47 (4) 1198-1207; DOI: 10.1183/13993003.01352-2015 Published 1 April 2016
  • Respiratory infections

    • Open Access
      Effects of PCV7 and PCV13 on invasive pneumococcal disease and carriage in Stockholm, Sweden
      Ilias Galanis, Ann Lindstrand, Jessica Darenberg, Sarah Browall, Priyanka Nannapaneni, Karin Sjöström, Eva Morfeldt, Pontus Naucler, Margareta Blennow, Åke Örtqvist, Birgitta Henriques-Normark
      European Respiratory Journal 47 (4) 1208-1218; DOI: 10.1183/13993003.01451-2015 Published 1 April 2016
      • Supplementary material
  • Respiratory infections and intensive care

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      Empiric antimicrobial therapy for ventilator-associated pneumonia after brain injury
      Antoine Roquilly, Fanny Feuillet, Philippe Seguin, Sigismond Lasocki, Raphael Cinotti, Yoann Launey, Lise Thioliere, Ronan Le Floch, Pierre Joachim Mahe, Nicolas Nesseler, Tanguy Cazaubiel, Bertrand Rozec, Didier Lepelletier, Véronique Sebille, Yannick Malledant, Karim Asehnoune for the ATLANREA group
      European Respiratory Journal 47 (4) 1219-1228; DOI: 10.1183/13993003.01314-2015 Published 1 April 2016
      • Supplementary material
      • Disclosures
  • Tuberculosis

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      Pharmacokinetics of ertapenem in patients with multidrug-resistant tuberculosis
      Sander P. van Rijn, Richard van Altena, Onno W. Akkerman, Dick van Soolingen, Tridia van der Laan, Wiel C.M. de Lange, Jos G.W. Kosterink, Tjip S. van der Werf, Jan-Willem C. Alffenaar
      European Respiratory Journal 47 (4) 1229-1234; DOI: 10.1183/13993003.01654-2015 Published 1 April 2016
      • Disclosures
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      Effectiveness and safety of meropenem/clavulanate-containing regimens in the treatment of MDR- and XDR-TB
      Simon Tiberi, Marie-Christine Payen, Giovanni Sotgiu, Lia D'Ambrosio, Valentina Alarcon Guizado, Jan Willem Alffenaar, Marcos Abdo Arbex, Jose A. Caminero, Rosella Centis, Saverio De Lorenzo, Mina Gaga, Gina Gualano, Aurora Jazmín Roby Arias, Anna Scardigli, Alena Skrahina, Ivan Solovic, Giorgia Sulis, Marina Tadolini, Onno W. Akkerman, Edith Alarcon Arrascue, Alena Aleska, Vera Avchinko, Eduardo Henrique Bonini, Félix Antonio Chong Marín, Lorena Collahuazo López, Gerard de Vries, Simone Dore, Heinke Kunst, Alberto Matteelli, Charalampos Moschos, Fabrizio Palmieri, Apostolos Papavasileiou, Antonio Spanevello, Dante Vargas Vasquez, Pietro Viggiani, Veronica White, Alimuddin Zumla, Giovanni Battista Migliori
      European Respiratory Journal 47 (4) 1235-1243; DOI: 10.1183/13993003.02146-2015 Published 1 April 2016

Review

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    Pulmonary mucosa-associated lymphoid tissue lymphoma revisited
    Raphael Borie, Marie Wislez, Martine Antoine, Christiane Copie-Bergman, Catherine Thieblemont, Jacques Cadranel
    European Respiratory Journal 47 (4) 1244-1260; DOI: 10.1183/13993003.01701-2015 Published 1 April 2016
    • Disclosures

Agora

  • Research letters

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      Inspiratory muscle training improves breathing pattern during exercise in COPD patients
      Noppawan Charususin, Rik Gosselink, Alison McConnell, Heleen Demeyer, Marko Topalovic, Marc Decramer, Daniel Langer
      European Respiratory Journal 47 (4) 1261-1264; DOI: 10.1183/13993003.01574-2015 Published 1 April 2016
      • Disclosures
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      Assessing small airway impairment in mild-to-moderate smoking asthmatic patients
      Marco Contoli, Federico Bellini, Luca Morandi, Giacomo Forini, Stefano Bianchi, Giulia Gnesini, Brunilda Marku, Klaus F. Rabe, Alberto Papi
      European Respiratory Journal 47 (4) 1264-1267; DOI: 10.1183/13993003.01708-2015 Published 1 April 2016
      • Disclosures
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      Decreased breath excretion of redox active iron in COPD: a protective failure?
      Sharon Mumby, Junpei Saito, Ian M. Adcock, Kian Fan Chung, Gregory J. Quinlan
      European Respiratory Journal 47 (4) 1267-1270; DOI: 10.1183/13993003.01710-2015 Published 1 April 2016
      • Disclosures
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      Proposed new definition of exercise pulmonary hypertension decreases false-positive cases
      Gabor Kovacs, Alexander Avian, Horst Olschewski
      European Respiratory Journal 47 (4) 1270-1273; DOI: 10.1183/13993003.01394-2015 Published 1 April 2016
      • Disclosures
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      Tuberculosis in migrants from 106 countries to Italy, 2008–2014
      Lanfranco Fattorini, Alessandro Mustazzolu, Emanuele Borroni, Giovanni Piccaro, Federico Giannoni, Daniela Maria Cirillo, the Italian Multicentre Study on Resistance to Antituberculosis Drugs (SMIRA) Group
      European Respiratory Journal 47 (4) 1273-1276; DOI: 10.1183/13993003.01844-2015 Published 1 April 2016
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      Interleukin-22 receptor is overexpressed in nonsmall cell lung cancer and portends a poor prognosis
      Antoine Guillon, Fabien Gueugnon, Konstantinos Mavridis, Emilie Dalloneau, Youenn Jouan, Patrice Diot, Nathalie Heuzé-Vourc'h, Yves Courty, Mustapha Si-Tahar
      European Respiratory Journal 47 (4) 1277-1280; DOI: 10.1183/13993003.01580-2015 Published 1 April 2016
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      Idelalisib-related pneumonitis
      Eglantine Haustraete, Julie Obert, Samia Diab, Sarah Abbes, Jean-Marc Zini, Sandrine Valade, Nathalie Lerolle, Nicolas Albin, Bertrand Arnulf, Jean-David Bouaziz, Claire Hussenet, Abdellatif Tazi, Anne Bergeron
      European Respiratory Journal 47 (4) 1280-1283; DOI: 10.1183/13993003.01670-2015 Published 1 April 2016
      • Disclosures
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      High-flow nasal oxygen for bronchoalveolar lavage in acute respiratory failure patients
      Béatrice La Combe, Jonathan Messika, Vincent Labbé, Keyvan Razazi, Bernard Maitre, Benjamin Sztrymf, Didier Dreyfuss, Muriel Fartoukh, Jean-Damien Ricard
      European Respiratory Journal 47 (4) 1283-1286; DOI: 10.1183/13993003.01883-2015 Published 1 April 2016
      • Disclosures
  • Correspondence

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      Is there still room for therapeutic drug monitoring of linezolid in patients with tuberculosis?
      Dario Cattaneo, Cristina Gervasoni, Emilio Clementi
      European Respiratory Journal 47 (4) 1287-1288; DOI: 10.1183/13993003.01913-2015 Published 1 April 2016
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      Is there still room for therapeutic drug monitoring of linezolid in patients with tuberculosis?
      Mathieu S. Bolhuis, Simon Tiberi, Giovanni Sotgiu, Saverio De Lorenzo, Jos G. Kosterink, Tjip S. van der Werf, Giovanni Battista Migliori, Jan-Willem Alffenaar
      European Respiratory Journal 47 (4) 1288-1290; DOI: 10.1183/13993003.02185-2015 Published 1 April 2016
      • Disclosures
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      Inclusion of children with airway disease for the development of spirometry reference data
      Anke Hüls, Ursula Krämer, Antje Schuster, Monika Gappa, Matthias Wisbauer, Christine Müller-Brandes, Tamara Schikowski, Barbara Hoffmann, Andrea von Berg, Dietrich Berdel
      European Respiratory Journal 47 (4) 1290-1292; DOI: 10.1183/13993003.01465-2015 Published 1 April 2016
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      Inclusion of children with airway disease for the development of spirometry reference data
      Sooky Lum, Janet Stocks
      European Respiratory Journal 47 (4) 1292-1293; DOI: 10.1183/13993003.02028-2015 Published 1 April 2016
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      Interstitial pneumonia with autoimmune features: the new consensus-based definition for this cohort of patients should be broadened
      Bridget Collins, Ganesh Raghu
      European Respiratory Journal 47 (4) 1293-1295; DOI: 10.1183/13993003.02084-2015 Published 1 April 2016
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      Interstitial pneumonia with autoimmune features: the new consensus-based definition for this cohort of patients should be broadened
      Aryeh Fischer, Harold R. Collard, Vincent Cottin on behalf of the “ERS/ATS Task Force on Undifferentiated Forms of Connective Tissue Disease-associated Interstitial Lung Disease”.
      European Respiratory Journal 47 (4) 1295-1296; DOI: 10.1183/13993003.00019-2016 Published 1 April 2016
      • Disclosures

Author correction

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    “Lung cancer survival in Norway, 1997–2011: from nihilism to optimism.” Yngvar Nilssen, Trond Eirik Strand, Lars Fjellbirkeland, Kristian Bartnes and Bjørn Møller. Eur Respir J 2016; 47: 275–287.
    European Respiratory Journal 47 (4) 1297; DOI: 10.1183/13993003.50650-2015 Published 1 April 2016
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European Respiratory Journal: 47 (4)
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