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Table of Contents

01 February 2016; volume 47, issue 2

Electronic Resources

  • You have accessRestricted access
    ERJ February Podcast: precision medicine in chronic airway diseases
    European Respiratory Journal 47 (2) E62; DOI: 10.1183/13993003.20164702.E62 Published 31 January 2016
    • ERJ Podcast

Editorials

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    Chronic diseases like asthma and COPD: do they truly exist?
    Peter J. Sterk
    European Respiratory Journal 47 (2) 359-361; DOI: 10.1183/13993003.01930-2015 Published 31 January 2016
    • ERJ Podcast
  • You have accessRestricted access
    Asthma phenotypes in childhood: conceptual thoughts on stability and transition
    Ben Daniel Spycher, Claudia Elisabeth Kuehni
    European Respiratory Journal 47 (2) 362-365; DOI: 10.1183/13993003.02011-2015 Published 31 January 2016
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    Stressful sleep
    Jonathan C. Jun, Vsevolod Y. Polotsky
    European Respiratory Journal 47 (2) 366-368; DOI: 10.1183/13993003.01920-2015 Published 31 January 2016
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    Incidence of venous thromboembolism in COPD: linking inflammation and thrombosis?
    Mareike Lankeit, Matthias Held
    European Respiratory Journal 47 (2) 369-373; DOI: 10.1183/13993003.01679-2015 Published 31 January 2016
    • Disclosures
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    Optimising treatment for post-operative lung cancer recurrence
    Dragan Subotic, Paul Van Schil, Bogdan Grigoriu
    European Respiratory Journal 47 (2) 374-378; DOI: 10.1183/13993003.01490-2015 Published 31 January 2016
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    Ageing lungs and very elderly COPD: anytime and anywhere
    Joan B. Soriano, Samy Suissa
    European Respiratory Journal 47 (2) 379-381; DOI: 10.1183/13993003.01806-2015 Published 31 January 2016
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    The bronchiectasis severity index and FACED score for bronchiectasis
    Wei-jie Guan, Rong-chang Chen, Nan-shan Zhong
    European Respiratory Journal 47 (2) 382-384; DOI: 10.1183/13993003.01717-2015 Published 31 January 2016
    • Disclosures
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    Treating allergic bronchopulmonary aspergillosis: the way forward
    Richard B. Moss
    European Respiratory Journal 47 (2) 385-387; DOI: 10.1183/13993003.01816-2015 Published 31 January 2016
    • Disclosures
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    Genetic testing in pulmonary hypertension: how should our clinical practice reflect recent advances?
    Mark Toshner
    European Respiratory Journal 47 (2) 388-389; DOI: 10.1183/13993003.01858-2015 Published 31 January 2016
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    Sex differences in pulmonary hypertension: are we cleaning up the mess?
    Tim Lahm
    European Respiratory Journal 47 (2) 390-393; DOI: 10.1183/13993003.01999-2015 Published 31 January 2016
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    Bedaquiline and multidrug-resistant tuberculosis: a systematic and critical analysis of the evidence
    Emanuele Pontali, Giovanni Sotgiu, Lia D'Ambrosio, Rosella Centis, Giovanni Battista Migliori
    European Respiratory Journal 47 (2) 394-402; DOI: 10.1183/13993003.01891-2015 Published 31 January 2016
    • Disclosures
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    European IPF Patient Charter: an SOS to the world
    Bruno Crestani
    European Respiratory Journal 47 (2) 403-405; DOI: 10.1183/13993003.01902-2015 Published 31 January 2016
    • Disclosures
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    Prenatal stress and childhood asthma risk: taking a broader view
    Alison Lee, Rosalind J. Wright
    European Respiratory Journal 47 (2) 406-409; DOI: 10.1183/13993003.01921-2015 Published 31 January 2016

Perspective

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    Treatable traits: toward precision medicine of chronic airway diseases
    Alvar Agusti, Elisabeth Bel, Mike Thomas, Claus Vogelmeier, Guy Brusselle, Stephen Holgate, Marc Humbert, Paul Jones, Peter G. Gibson, Jørgen Vestbo, Richard Beasley, Ian D. Pavord
    European Respiratory Journal 47 (2) 410-419; DOI: 10.1183/13993003.01359-2015 Published 31 January 2016
    • Disclosures
    • ERJ Podcast

Task Force Reports

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    Report of the European Respiratory Society/European Cystic Fibrosis Society task force on the care of adults with cystic fibrosis
    J. Stuart Elborn, Scott C. Bell, Susan L. Madge, Pierre-Regis Burgel, Carlo Castellani, Steven Conway, Karleen De Rijcke, Birgit Dembski, Pavel Drevinek, Harry G.M. Heijerman, J. Alistair Innes, Anders Lindblad, Bruce Marshall, Hanne V. Olesen, Andreas L. Reimann, Ampara Solé, Laura Viviani, Thomas O.F. Wagner, Tobias Welte, Francesco Blasi
    European Respiratory Journal 47 (2) 420-428; DOI: 10.1183/13993003.00592-2015 Published 31 January 2016
    • Disclosures
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    Use of exercise testing in the evaluation of interventional efficacy: an official ERS statement
    Luis Puente-Maestu, Paolo Palange, Richard Casaburi, Pierantonio Laveneziana, François Maltais, J. Alberto Neder, Denis E. O'Donnell, Paolo Onorati, Janos Porszasz, Roberto Rabinovich, Harry B. Rossiter, Sally Singh, Thierry Troosters, Susan Ward
    European Respiratory Journal 47 (2) 429-460; DOI: 10.1183/13993003.00745-2015 Published 31 January 2016
    • Disclosures
    • Supplementary material

Original Articles

  • COPD and lung function

    • Open Access
      Incidence of airflow limitation in subjects 65–100 years of age
      Johannes A. Luoto, Sölve Elmståhl, Per Wollmer, Mats Pihlsgård
      European Respiratory Journal 47 (2) 461-472; DOI: 10.1183/13993003.00635-2015 Published 31 January 2016
      • Disclosures
  • COPD and venous thromboembolism

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      COPD and risk of venous thromboembolism and mortality in a general population
      Trond Børvik, Sigrid K. Brækkan, Kristin Enga, Henrik Schirmer, Ellen E. Brodin, Hasse Melbye, John-Bjarne Hansen
      European Respiratory Journal 47 (2) 473-481; DOI: 10.1183/13993003.00402-2015 Published 31 January 2016
      • Supplementary material
  • Bronchiectasis

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      Predicting mortality in bronchiectasis using bronchiectasis severity index and FACED scores: a 19-year cohort study
      Huw C. Ellis, Steven Cowman, Michele Fernandes, Robert Wilson, Michael R. Loebinger
      European Respiratory Journal 47 (2) 482-489; DOI: 10.1183/13993003.01312-2015 Published 31 January 2016
      • Supplementary material
  • Asthma

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      A randomised trial of glucocorticoids in acute-stage allergic bronchopulmonary aspergillosis complicating asthma
      Ritesh Agarwal, Ashutosh N. Aggarwal, Sahajal Dhooria, Inderpaul Singh Sehgal, Mandeep Garg, Biman Saikia, Digambar Behera, Arunaloke Chakrabarti
      European Respiratory Journal 47 (2) 490-498; DOI: 10.1183/13993003.01475-2015 Published 31 January 2016
      • Supplementary material
  • Paediatric pneumology

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      Change in the manifestations of asthma and asthma-related traits in childhood: a latent transition analysis
      Frances L. Garden, Judy M. Simpson, Craig M. Mellis, Guy B. Marks for the CAPS Investigators
      European Respiratory Journal 47 (2) 499-509; DOI: 10.1183/13993003.00284-2015 Published 31 January 2016
      • Supplementary material
      • Disclosures
    • You have accessRestricted access
      Childhood wheezing phenotypes influence asthma, lung function and exhaled nitric oxide fraction in adolescence
      Liesbeth Duijts, Raquel Granell, Jonathan A.C. Sterne, A. John Henderson
      European Respiratory Journal 47 (2) 510-519; DOI: 10.1183/13993003.00718-2015 Published 31 January 2016
      • Supplementary material
      • Disclosures
  • Cystic fibrosis

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      Vitamin D represses rhinovirus replication in cystic fibrosis cells by inducing LL-37
      Aline Schögler, Ricardo J. Muster, Elisabeth Kieninger, Carmen Casaulta, Caroline Tapparel, Andreas Jung, Alexander Moeller, Thomas Geiser, Nicolas Regamey, Marco P. Alves
      European Respiratory Journal 47 (2) 520-530; DOI: 10.1183/13993003.00665-2015 Published 31 January 2016
  • Sleep

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      Sleep apnoea and the hypothalamic–pituitary–adrenal axis in men and women: effects of continuous positive airway pressure
      Ilia Kritikou, Maria Basta, Alexandros N. Vgontzas, Slobodanka Pejovic, Julio Fernandez-Mendoza, Duanping Liao, Edward O. Bixler, Jordan Gaines, George P. Chrousos
      European Respiratory Journal 47 (2) 531-540; DOI: 10.1183/13993003.00319-2015 Published 31 January 2016
      • Disclosures
  • Pulmonary vascular diseases

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      Genetic counselling in a national referral centre for pulmonary hypertension
      Barbara Girerd, David Montani, Xavier Jaïs, Mélanie Eyries, Azzedine Yaici, Benjamin Sztrymf, Laurent Savale, Florence Parent, Florence Coulet, Laurent Godinas, Edmund M. Lau, Yuichi Tamura, Olivier Sitbon, Florent Soubrier, Gérald Simonneau, Marc Humbert
      European Respiratory Journal 47 (2) 541-552; DOI: 10.1183/13993003.00717-2015 Published 31 January 2016
      • Supplementary material
      • Disclosures
  • Right ventricle function

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      Oestradiol metabolism and androgen receptor genotypes are associated with right ventricular function
      Corey E. Ventetuolo, Nandita Mitra, Fei Wan, Ani Manichaikul, R. Graham Barr, Craig Johnson, David A. Bluemke, Joao A.C. Lima, Hari Tandri, Pamela Ouyang, Steven M. Kawut
      European Respiratory Journal 47 (2) 553-563; DOI: 10.1183/13993003.01083-2015 Published 31 January 2016
      • Disclosures
      • Supplementary material
  • Tuberculosis

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      Bedaquiline in the treatment of multidrug- and extensively drug-resistant tuberculosis
      Alexander S. Pym, Andreas H. Diacon, Shen-Jie Tang, Francesca Conradie, Manfred Danilovits, Charoen Chuchottaworn, Irina Vasilyeva, Koen Andries, Nyasha Bakare, Tine De Marez, Myriam Haxaire-Theeuwes, Nacer Lounis, Paul Meyvisch, Ben Van Baelen, Rolf P.G. van Heeswijk, Brian Dannemann on behalf of the TMC207-C209 Study Group
      European Respiratory Journal 47 (2) 564-574; DOI: 10.1183/13993003.00724-2015 Published 31 January 2016
      • Supplementary material
      • Disclosures
    • You have accessRestricted access
      Cost–benefit analysis of Xpert MTB/RIF for tuberculosis suspects in German hospitals
      Roland Diel, Albert Nienhaus, Doris Hillemann, Elvira Richter
      European Respiratory Journal 47 (2) 575-587; DOI: 10.1183/13993003.01333-2015 Published 31 January 2016
      • Supplementary material
      • Disclosures
  • Interstitial lung diseases

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      Predictors of mortality in rheumatoid arthritis-associated interstitial lung disease
      Joshua J. Solomon, Jonathan H. Chung, Gregory P. Cosgrove, M. Kristen Demoruelle, Evans R. Fernandez-Perez, Aryeh Fischer, Stephen K. Frankel, Stephen B. Hobbs, Tristan J. Huie, Jill Ketzer, Amar Mannina, Amy L. Olson, Gloria Russell, Yutaka Tsuchiya, Zulma X. Yunt, Pearlanne T. Zelarney, Kevin K. Brown, Jeffrey J. Swigris
      European Respiratory Journal 47 (2) 588-596; DOI: 10.1183/13993003.00357-2015 Published 31 January 2016
      • Supplementary material
      • Disclosures
    • You have accessRestricted access
      European IPF Patient Charter: unmet needs and a call to action for healthcare policymakers
      Francesco Bonella, Marlies Wijsenbeek, Maria Molina-Molina, Annette Duck, Rosalba Mele, Klaus Geissler, Wim Wuyts
      European Respiratory Journal 47 (2) 597-606; DOI: 10.1183/13993003.01204-2015 Published 31 January 2016
      • Supplementary material
      • Disclosures
  • Lung cancer

    • You have accessRestricted access
      Sequential multimodality bronchoscopic investigation of peripheral pulmonary lesions
      Daniel P. Steinfort, Asha Bonney, Katharine See, Louis B. Irving
      European Respiratory Journal 47 (2) 607-614; DOI: 10.1183/13993003.00786-2015 Published 31 January 2016
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      Clinical features of large cell neuroendocrine carcinoma: a population-based overview
      Jules L. Derks, Lizza E. Hendriks, Wieneke A. Buikhuisen, Harry J.M. Groen, Erik Thunnissen, Robert-Jan van Suylen, Ruud Houben, Ronald A. Damhuis, Ernst J.M. Speel, Anne-Marie C. Dingemans
      European Respiratory Journal 47 (2) 615-624; DOI: 10.1183/13993003.00618-2015 Published 31 January 2016

Review

  • Open Access
    A review of national guidelines for management of COPD in Europe
    Marc Miravitlles, Claus Vogelmeier, Nicolas Roche, David Halpin, João Cardoso, Alexander G. Chuchalin, Hannu Kankaanranta, Thomas Sandström, Paweł Śliwiński, Jaromir Zatloukal, Francesco Blasi
    European Respiratory Journal 47 (2) 625-637; DOI: 10.1183/13993003.01170-2015 Published 31 January 2016
    • Supplementary material
    • Disclosures

State of the Art

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    Inflammatory bowel diseases, chronic liver diseases and the lung
    Roberto Rodriguez-Roisin, Sonja D. Bartolome, Gérard Huchon, Michael J. Krowka
    European Respiratory Journal 47 (2) 638-650; DOI: 10.1183/13993003.00647-2015 Published 31 January 2016
    • Disclosures

Agora

  • Research letters

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      Lung function changes over time following withdrawal of inhaled corticosteroids in patients with severe COPD
      Helgo Magnussen, Kay Tetzlaff, Eric D. Bateman, Henrik Watz, Anne M. Kirsten, Emiel F.M. Wouters, Bernd Disse, Helen Finnigan, Roberto Rodriguez-Roisin, Peter M.A. Calverley
      European Respiratory Journal 47 (2) 651-654; DOI: 10.1183/13993003.01644-2015 Published 31 January 2016
      • Disclosures
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      Bacteraemia in outpatients with community-acquired pneumonia
      Catia Cillóniz, Albert Gabarrús, Jordi Almirall, Rosanel Amaro, Mariano Rinaudo, Chiara Travierso, Michael Niederman, Antoni Torres
      European Respiratory Journal 47 (2) 654-657; DOI: 10.1183/13993003.01308-2015 Published 31 January 2016
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      Improving end-of-life communication between primary and secondary care within respiratory medicine
      Alison C. Boland, Claire Hodgekiss, Fiona Hicks, Annette Edwards, Ian J. Clifton
      European Respiratory Journal 47 (2) 658-660; DOI: 10.1183/13993003.01549-2015 Published 31 January 2016
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      QuantiFERON-TB performance enhanced by novel Mycobacterium tuberculosis-specific antigens
      Monica Losi, Ashley J. Knights, Francesca Mariani, Alfonso M. Altieri, Gregorino Paone, Andre G. Loxton, Novel N. Chegou, John Kenneth, Mario G. Alma, Vittorio Colizzi, Gerhard Walzl, Cesare Saltini, Jeff Boyle, Massimo Amicosante
      European Respiratory Journal 47 (2) 660-664; DOI: 10.1183/13993003.01015-2015 Published 31 January 2016
      • Disclosures
    • You have accessRestricted access
      Tuberculosis elimination, patients' lives and rational use of new drugs: revisited
      Simon Tiberi, Lia D'Ambrosio, Saverio De Lorenzo, Pietro Viggiani, Rosella Centis, Giovanni Battista Migliori
      European Respiratory Journal 47 (2) 664-667; DOI: 10.1183/13993003.01297-2015 Published 31 January 2016
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      Tuberculosis in Germany: a declining trend coming to an end?
      Lena Fiebig, Barbara Hauer, Bonita Brodhun, Doris Altmann, Walter Haas
      European Respiratory Journal 47 (2) 667-670; DOI: 10.1183/13993003.01410-2015 Published 31 January 2016
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      Recruitment challenges for clinical trials with novel regimens for drug-resistant tuberculosis
      Sweetness Siwendu, Melissa Mitchell, Andreas H. Diacon, Florian von Groote-Bidlingmaier
      European Respiratory Journal 47 (2) 670-672; DOI: 10.1183/13993003.01330-2015 Published 31 January 2016
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      Pulmonary artery diameter to predict pulmonary hypertension in pulmonary sarcoidosis
      Marloes P. Huitema, Marcela Spee, Veronique M.M. Vorselaars, Sanne Boerman, Repke J. Snijder, Hendrik W. van Es, Herre J. Reesink, Jan C. Grutters, Marco C. Post
      European Respiratory Journal 47 (2) 673-676; DOI: 10.1183/13993003.01319-2015 Published 31 January 2016
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      Pulmonary hypertension associated with ponatinib therapy
      Fleur-Marie Quilot, Marjolaine Georges, Nicolas Favrolt, Guillaume Beltramo, Clément Foignot, Aurélie Grandvuillemin, David Montani, Philippe Bonniaud, Philippe Camus
      European Respiratory Journal 47 (2) 676-679; DOI: 10.1183/13993003.01110-2015 Published 31 January 2016
      • Disclosures
  • Correspondence

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      End TB with precision treatment!
      Evelien P.M. van der Burgt, Marieke G.G. Sturkenboom, Mathieu S. Bolhuis, Onno W. Akkerman, Jos G.W. Kosterink, Wiel C.M. de Lange, Frank G.J. Cobelens, Tjip S. van der Werf, Jan-Willem C. Alffenaar
      European Respiratory Journal 47 (2) 680-682; DOI: 10.1183/13993003.01285-2015 Published 31 January 2016
    • You have accessRestricted access
      β-blockers in pulmonary arterial hypertension: generation might matter
      Simon Malenfant, Frédéric Perros
      European Respiratory Journal 47 (2) 682-684; DOI: 10.1183/13993003.01244-2015 Published 31 January 2016
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      Cameroon's MDR-TB treatment programme jeopardised by cross-border migration
      Jürgen Noeske, Jean-Louis Abena Foe, Christopher Kuaban
      European Respiratory Journal 47 (2) 684-686; DOI: 10.1183/13993003.01324-2015 Published 31 January 2016
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      Cameroon's multidrug-resistant tuberculosis treatment programme jeopardised by cross-border migration
      Alberto Matteelli, Knut Lönnroth, Davide Mosca, Haileyesus Getahun, Rosella Centis, Lia D'Ambrosio, Ernesto Jaramillo, Giovanni Battista Migliori, Mario C. Raviglione
      European Respiratory Journal 47 (2) 686-688; DOI: 10.1183/13993003.01597-2015 Published 31 January 2016
      • Disclosures
    • You have accessRestricted access
      Is there hope of improving the prognosis of pulmonary tumour thrombotic microangiopathy?
      Mansouria Merad, Laurent Savale, Sami Antoun, François Vincent for the GrrrOH: Groupe de Recherche en Réanimation Respiratoire en Onco-Hématologie (Group for Research in Respiratory Intensive Care Onco-Hematology)
      European Respiratory Journal 47 (2) 688-690; DOI: 10.1183/13993003.01276-2015 Published 31 January 2016
    • You have accessRestricted access
      Earlier diagnosis and international registries may improve outcomes in pulmonary tumour thrombotic microangiopathy
      Laura C. Price, S. John Wort
      European Respiratory Journal 47 (2) 690-691; DOI: 10.1183/13993003.01736-2015 Published 31 January 2016

Erratum

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    “Cladribine improves lung cysts and pulmonary function in a child with histiocytosis.” Ralph Epaud, Hubert Ducou Le Pointe, Sylvie Fasola, Sandra Ploussard, Celine Delestrain, Chiara Sileo and Jean Donadieu. Eur Respir J 2015; 45: 831–833.
    European Respiratory Journal 47 (2) 692; DOI: 10.1183/09031936.50146114 Published 31 January 2016
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European Respiratory Journal: 47 (2)
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