Skip to main content

Main menu

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • COVID-19 submission information
    • Peer reviewer login
  • Alerts
  • Podcasts
  • Subscriptions
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

User menu

  • Log in
  • Subscribe
  • Contact Us
  • My Cart

Search

  • Advanced search
  • ERS Publications
    • European Respiratory Journal
    • ERJ Open Research
    • European Respiratory Review
    • Breathe
    • ERS Books
    • ERS publications home

Login

European Respiratory Society

Advanced Search

  • Home
  • Current issue
  • ERJ Early View
  • Past issues
  • Authors/reviewers
    • Instructions for authors
    • Submit a manuscript
    • Open access
    • COVID-19 submission information
    • Peer reviewer login
  • Alerts
  • Podcasts
  • Subscriptions

Changes in the incidence, prevalence and mortality of bronchiectasis in the UK from 2004 to 2013: a population-based cohort study

Jennifer K. Quint, Elizabeth R.C. Millett, Miland Joshi, Vidya Navaratnam, Sara L. Thomas, John R. Hurst, Liam Smeeth, Jeremy S. Brown
European Respiratory Journal 2016 47: 186-193; DOI: 10.1183/13993003.01033-2015
Jennifer K. Quint
1Dept of Respiratory Epidemiology, Occupational Medicine and Public Health, National Heart and Lung Institute, Imperial College London, London, UK
2Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: j.quint@imperial.ac.uk
Elizabeth R.C. Millett
2Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Miland Joshi
1Dept of Respiratory Epidemiology, Occupational Medicine and Public Health, National Heart and Lung Institute, Imperial College London, London, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Vidya Navaratnam
3Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sara L. Thomas
2Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
John R. Hurst
4Centre for Inflammation and Tissue Repair, UCL Respiratory, University College London, London, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Liam Smeeth
2Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jeremy S. Brown
4Centre for Inflammation and Tissue Repair, UCL Respiratory, University College London, London, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • PDF
Loading

Figures

  • Tables
  • Additional Files
  • FIGURE 1
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIGURE 1

    Incidence of bronchiectasis in the UK from 2004 to 2013 stratified by age in a) men and b) women.

  • FIGURE 2
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIGURE 2

    Prevalence of bronchiectasis in the UK from 2004 to 2013 stratified by age in a) men and b) women.

Tables

  • Figures
  • Additional Files
  • TABLE 1

    Incidence of bronchiectasis in 2004 and 2013 stratified by sex and age group

    Age yearsMenWomenOverall
    200420132004201320042013
    18–292.44 (0.696–8.56)1.48 (0.296–7.41)1.54 (0.317–7.47)1.55 (0.321–7.482)2.01 (0.51–8.01)1.52 (0.31–7.45)
    30–393.08 (1.01–9.41)4.14 (1.58–10.85)3.18 (1.06–9.55)5.36 (2.30–12.50)3.13 (1.03–9.47)4.75 (1.93–11.68)
    40–497.74 (3.29–15.66)9.28 (4.88–17.66)8.95 (4.65–17.23)13.63 (8.02–23.18)8.34 (4.23–16.44)11.44 (6.41–20.42)
    50–5919.91 (12.83–30.89)26.36 (18.00–38.61)29.51 (20.57–42.33)35.96 (25.94–49.86)24.66 (16.62–36.59)31.13 (21.91–44.24)
    60–6949.68 (37.62–65.60)58.06 (44.90–75.09)60.55 (47.07–77.89)86.07 (69.69–106.3)55.17 (42.38–71.82)72.31 (57.43–91.05)
    70–7973.82 (58.77–92.73)126.66 (106.43–150.74)66.32 (52.14–84.36)124.94 (104.86–148.87)69.72 (55.14–88.16)125.74 (105.59–149.74)
    ≥8077.68 (62.20–97.02)117.47 (98.05–140.74)41.57 (30.68–56.34)97.85 (80.27–119.28)54.02 (41.38–70.52)105.38 (87.08–127.54)
    • Data are presented as incidence rate (95% CI), per 100 000 person-years.

  • TABLE 2

    Prevalence of bronchiectasis in 2004 and 2013 stratified by sex and age group

    Age yearsMenWomenOverall
    200420132004201320042013
    18–2928.8 (20.2–33.3)43.3 (32.2–58.3)29.7 (20.8–42.5)43.6 (32.4–58.6)29.3 (20.4–41.9)43.4 (32.3–58.4)
    30–3938.7 (28.3–53.0)58.2 (45.0–75.2)53.4 (40.8–69.8)79.3 (63.7–98.8)46.0 (34.5–61.4)68.8 (54.3–87.0)
    40–4985.2 (68.9–105.3)97.4 (79.9–118.7)110.7 (91.9–133.3)142.1 (120.6–167.4)98.0 (80.4–119.4)119.8 (100.2–143.2)
    50–59286.9 (255.6–322.0)224.0 (196.5–255.3)391.1 (354.3–431.7)285.9 (254.6–321.0)339.0 (304.8–377.0)254.9 (225.5–288.2)
    60–69477.4 (436.5–522.1)629.3 (582.1–680.2)638.4 (590.9–689.7)866.0 (810.4–925.3)557.9 (513.6–606.0)747.7 (696.1–803.0)
    70–79608.0 (561.7–658.1)1109.0 (1045.9–1175.8)698.1 (648.4–751.6)1370.3 (1300.1–1444.2)653.0 (605.0–704.9)1239.7 (1172.9–1310.1)
    ≥80583.0 (537.7–632.1)1236.9 (1170.2–1307.3)532.3 (489.1–579.3)1175.6 (1110.6–1244.3)557.7 (513.4–605.8)1206.3 (1140.5–1275.8)
    • Data are presented as prevalence (95% CI), per 100 000.

  • TABLE 3

    Baseline characteristics of the bronchiectasis study population

    Study population18 793
    Age at diagnosis years61.8 (47.5–72.2)
    Length of time in study years7.2 (3.6–7.9)
    Sex
     Male7798 (41.5)
     Female10 995 (58.5)
    Smoking habit#
     Never-smoker/not recorded6003 (31.9)
     Ex-smoker7118 (37.9)
     Current smoker5672 (30.2)
    Index of multiple deprivation
     1 (least deprived)3082 (16.4)
     23013 (16.0)
     32243 (11.9)
     41935 (10.3)
     5 (most deprived)1728 (9.2)
     Unavailable6792 (36.1)
    • Data are presented as n, median (interquartile range) or n (%). #: ever, closest to diagnosis date.

  • TABLE 4

    Coexisting diagnoses associated with bronchiectasis#

    Study population18 793
    Asthma7988 (42.5)
    Chronic obstructive pulmonary disease6774 (36.1)
    HIV1300 (6.9)
    Rheumatoid arthritis1163 (6.2)
    Other connective tissue diseases969 (5.2)
    Inflammatory bowel disease527 (2.8)
    Bone marrow transplant20 (0.11)
    Hypogammaglobulinaemia172 (0.9)
    Allergic bronchopulmonary aspergillosis339 (1.8)
    None of these comorbidities6422 (34.2)
    • Data are presented as n or n (%). #: some patients had multiple comorbidities.

  • TABLE 5

    Crude mortality rates by age group in 2010

    Age yearsMenWomen
    General populationBronchiectasis cohortGeneral populationBronchiectasis cohort
    18–491.3 (1.3–1.4)13.1 (3.4–22.8)0.8 (0.7–0.8)6.4 (0.8–12.0)
    50–595.1 (5.0–5.2)10.0 (2.6–17.3)3.4 (3.4–3.5)7.8 (2.4–13.2)
    60–6912.5 (12.3–12.6)29.5 (20.6–38.4)7.9 (7.8–8.0)16.0 (10.6–21.5)
    70–7933.77 (33.4–33.9)58.6 (46.4–70.7)22.8 (22.6–23.0)43.9 (34.9–52.8)
    ≥80111.8 (111.1–112.5)144.6 (115.4–173.9)98.9 (98.4–99.4)160.1 (136.1–184.1)
    • Data are presented as mortality rate (95% CI), per 1000 population. Rates have been calculated using a mid-year population estimate for 2010.

Additional Files

  • Figures
  • Tables
  • Disclosures

    • J.R. Hurst
    • J.K. Quint
    • L. Smeeth
  • Supplementary material

    Please note: supplementary material is not edited by the Editorial Office, and is uploaded as it has been supplied by the author.

    • Supplementary material - Read codes for bronchiectasis
PreviousNext
Back to top
View this article with LENS
Vol 47 Issue 1 Table of Contents
European Respiratory Journal: 47 (1)
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
Email

Thank you for your interest in spreading the word on European Respiratory Society .

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Changes in the incidence, prevalence and mortality of bronchiectasis in the UK from 2004 to 2013: a population-based cohort study
(Your Name) has sent you a message from European Respiratory Society
(Your Name) thought you would like to see the European Respiratory Society web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
Citation Tools
Changes in the incidence, prevalence and mortality of bronchiectasis in the UK from 2004 to 2013: a population-based cohort study
Jennifer K. Quint, Elizabeth R.C. Millett, Miland Joshi, Vidya Navaratnam, Sara L. Thomas, John R. Hurst, Liam Smeeth, Jeremy S. Brown
European Respiratory Journal Jan 2016, 47 (1) 186-193; DOI: 10.1183/13993003.01033-2015

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Changes in the incidence, prevalence and mortality of bronchiectasis in the UK from 2004 to 2013: a population-based cohort study
Jennifer K. Quint, Elizabeth R.C. Millett, Miland Joshi, Vidya Navaratnam, Sara L. Thomas, John R. Hurst, Liam Smeeth, Jeremy S. Brown
European Respiratory Journal Jan 2016, 47 (1) 186-193; DOI: 10.1183/13993003.01033-2015
del.icio.us logo Digg logo Reddit logo Technorati logo Twitter logo CiteULike logo Connotea logo Facebook logo Google logo Mendeley logo
Full Text (PDF)

Jump To

  • Article
    • Abstract
    • Abstract
    • Introduction
    • Methods
    • Results
    • Discussion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • PDF

Subjects

  • CF and non-CF bronchiectasis
  • Tweet Widget
  • Facebook Like
  • Google Plus One

More in this TOC Section

Original Articles

  • Systematic assessment of respiratory health in illness susceptible athletes
  • Identifying early PAH biomarkers in systemic sclerosis
  • Viable virus aerosol propagation by PAP circuit leak
Show more Original Articles

Bronchiectasis

  • Tiotropium treatment for bronchiectasis
  • Heterogeneity of treatment response in bronchiectasis
  • Psychometrics of HRQoL questionnaires in bronchiectasis
Show more Bronchiectasis

Related Articles

Navigate

  • Home
  • Current issue
  • Archive

About the ERJ

  • Journal information
  • Editorial board
  • Reviewers
  • Press
  • Permissions and reprints
  • Advertising

The European Respiratory Society

  • Society home
  • myERS
  • Privacy policy
  • Accessibility

ERS publications

  • European Respiratory Journal
  • ERJ Open Research
  • European Respiratory Review
  • Breathe
  • ERS books online
  • ERS Bookshop

Help

  • Feedback

For authors

  • Instructions for authors
  • Publication ethics and malpractice
  • Submit a manuscript

For readers

  • Alerts
  • Subjects
  • Podcasts
  • RSS

Subscriptions

  • Accessing the ERS publications

Contact us

European Respiratory Society
442 Glossop Road
Sheffield S10 2PX
United Kingdom
Tel: +44 114 2672860
Email: journals@ersnet.org

ISSN

Print ISSN:  0903-1936
Online ISSN: 1399-3003

Copyright © 2022 by the European Respiratory Society