Abstract
Background: The importance of pulmonary hypertension [PHT] is newly recognised entity among hemodialysis [HD] patients and its prevelanceis reported 30 to 60%.
Aim and Objectives: We aimed to investigate the relationship between fluid status and PHT in HD patients
Methods: A total of 77 HD patients were enrolled in the study.Multifrequency bioimpedance analysis [BIA] was used to assess fluid status and performed just before and 30 minutes after the midweek HD.Fluid overload was defined as a OH/ECW ≥7%. Echocardiographic examinations were performed. PHT was defined as systolic pulmonary artery pressure [sPAP] higher than 35 mmHg at rest.
Results: sPAP, OH/ECW levels and the frequency of PHT were significanly reduced after HD . OH/ECW and the frequency of fluid overload were significantly higher in patients with PHT than in those without, whereas serum albumin and haemoglobin levels were significantly lower .
Conclusion: This study revealed that fluid overload is closely associated with PHT. Intervention to reduce excess volume in this patient cohort can reduce pulmonary hypertension.
- Copyright ©ERS 2015
