Abstract
Backround: Osteoporosis has an impact on the outcome of lung transplantation and therefore is considered as a relative contrindication. It is documented that bone mineral density(BMD) decreases 4-12% in the first 3-6 months after transplantation due to corticosteroids and immunosuppressive drugs. In this study we aim to investigate the prevalance of osteoporosis/osteopenia in patientswho applied to our department with end-staged lung disease.
Method: Bone mineral density was routinly measured as a part of preoperative investigations in patients who were candidates for lung transplantation. Depending on T-score, patients were grouped as osteopenia (T score between -1 and -2.5) and osteoporosis (T score below -2.5). Data was retrospectively analyised.
Results: During the study period (2012-14), total 134 patients were evaluated in our department. T- score determined osteopenia in 49 (37%) and osteoporosis in 58 (43%) patients. Subgroup of indications were reported in table 1.
Outcome: These findings determine that abnormal BMD is extremely common (80%) in patients presenting with end-staged lung disease. We suggest that the supportive treatment of these patients in the long term has to be revised in this regard. This is the only way to eleminate one of preventable co-morditidies along the course of lung transplantation.
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