Abstract
Background: Tuberculosis drug resistance is a Global treat now a days. The impact of Multi drug resistant tuberculosis is dangerous especially in resource limited countries like Ethiopia because of its financial and skilled human power required for diagnosis and management.
Objective: To determine risk factor and resistance pattern of MDR TB among case suspected clients in Oromia Regional State, Oromia, Ethiopia.
Methods: The study was conducted by employing a case control study design to determine the predictors of MDR TB among case confirmed in Oromia Regional State.
Results: Of 265 samples confirmed to have Mycobacterium tuberculosis and subjected to drug susceptibility testing 33. 22% were MDR-Mycobacterium tuberculosis while 66.79% were non MDR-Mycobacterium tuberculosis. Accordingly 88 case and 177 control data were considered for processing. Bi-variate analysis reveals rural residence, tertiary education, alcoholism and anti-acid use for gastritis during TB treatment are statistically associated with MDR TB. In the multi-variate analysis; four exposure variables namely occupation/farmer/ AOR= 4.8%, TB patient contact history AOR= 6.6% HIV infection AOR= 1.4% and pervious TB treatment outcome AOR 3.5%were found to be independent risk factors of MDR TB after adjusting for other variables.
Conclusion: TB patient contact history should considered not only as the source of infection but also MD RT affecting factor, HIV infected patients and previously treated TB patients should screened for MDR TB.
- Copyright ©ERS 2015