Abstract
Predicted postoperative (PPO) underestimate lung function and exercise capacity after resection in patients with lung cancer. Prediction is also very important for patients with symptomatic bronchiectasis.
Methods: Prospective study to evaluate the accuracy of ppo FEV1, DLCO and VO2 prediction in patients with bronchiectasis who undergo anatomic lung resection.
Results: After 9 months we analyzed 44 patients. Data comparing PPO FEV1, DLCO, VO2max and the observed after surgery is summarized in . When we evaluate the difference in percentage of the observed values after surgery, we found that the majority (± 77%) had values above the PPO. Using the preoperative predictive values of FEV1, DLCO and VO2max as zero, we can note the number of patients above this baseline and how much (%) they are over the PPO.
| FEV1 (L) | PPO | 3M | 9M |
| (n 44) | 1,7 (0,7) | 1,9 (0,8) a | 2,0 (0,8) b |
| DLCO mL/min/mmHg | PPO | 3M | 9M |
| (n 37) | 18,0 (6,6) | 21,5 (5,6) c | 21,7 (8,2) d |
| VO2 mL/Kg/min | PPO | 3M | max 9M |
| (n 44) | 16,2 (6,8) | 19,3 (6,4) e | 20,2 (8,0) f |
mean values (standard deviation) and p values compares PPO to 3 and 9 months: a p 0,216 / b p 0,109 / c p 0,026 / d p 0,049 / e p 0,035 / f p 0,016
Conclusion: PPO underestimates the postoperative DLCO and VO2 values, the two most related parameters with the morbidity and mortality in patients with bronchiectasis who undergo resection.
- Copyright ©ERS 2015
