Abstract
Background: Pathological diagnosis is an integral part for diagnosis of diffuse lung diseases with failed diagnosis by less invasive facilities.
Objectives: Evaluate safety& diagnostic yield of lung biopsy by VAMT in cases of diffuse pulmonary infiltrates.
Methods: Prospective study of VAMT lung biopsy in cases with diffuse pulmonary infiltrates (during 2014) including (18) patient (mean age 45.56 - 66.7% females).after failed diagnosis by less invasive facility with follow up for any complication
Results: Convenient biopsy specimens were obtained in all patients -Number of biopsies taken in each patient ranges from (2) to (6)-mean 2.93 ±1.16 SD-Duration of ICT ranged from (1) day to (7) days mean 3.11 ± 1.68 SD.–diagnostic yield was 100% -UIP pattern was the commonest diagnosis (38.9%).followed by adenocarcinoma (22.2%). 11.1% for NSIP- (5.6% for each of BOOP,SILCOSIS,lymphoma, RB-ILD and TB .No major complication(no respiratory failure requiring ICU admission and no mortality ).minor bleeding at biopsy site in50 % surgical emphysema in 27.8%-infection in 5.6%.
Conclusion: Lung sampling can be performed safely by VAMT with good diagnostic yield in cases of diffuse lung infiltrates of unknown origin and represent agood alternative for VATS & open biopsy.
- Copyright ©ERS 2015
