Outcome and prognostic factors of patients with lung cancer admitted to intensive care unit

Abstract

Backgrounds: Lung cancer is the leading cause of cancer mortality worldwide and often needs for the intensive care. Although techniques of critical care are developing and expanding rapidly, Decision for intensive treatment of patients with lung cancer is difficult. We are evaluated outcome and prognostic factors of patients with lung cancer admitted to intensive care unit.

Methods: We retrospectively analyzed the clinical data of 123 patients with lung cancer admitted to intensive care unit (ICU) from October 2008 to January 2012.

Results: The median age of patients with lung cancer admitted to ICU was 68 years, and 79 patients were male. 74 patients with lung cancer were medical ICU and their ICU mortality was 42%. Cox's regression hazard model revealed that the use of vasopressor (HR 54.694 CI 5.549-539.060, p = 0.001) and admission from ward (HR 9.520, CI 1.287-74.441, p = 0.027) were independent predictive factors for mortality in patients with lung cancer admitted to the ICU.

Conclusion: The use of vasopressor and admission from ward should be considered when estimating prognosis and mortality in patients with lung cancer admitted to the ICU.