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Prevalence of COPD in vascular diseases

BV Muralimohan, Gayatri Ekbote, Syed Zulkharnain Tousheed, Ranganath Ramanjenaya
European Respiratory Journal 2015 46: PA1131; DOI: 10.1183/13993003.congress-2015.PA1131
BV Muralimohan
1Pulmonology, Narayana Health, Bangalore, Karnataka India
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Gayatri Ekbote
1Pulmonology, Narayana Health, Bangalore, Karnataka India
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Syed Zulkharnain Tousheed
1Pulmonology, Narayana Health, Bangalore, Karnataka India
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Ranganath Ramanjenaya
1Pulmonology, Narayana Health, Bangalore, Karnataka India
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Abstract

Introduction: Cardiovascular disease (CVD) [comprising coronary artery disease (CAD), cerebro-vascular disease (CeVD), peripheral vascular disease (PVD)] and chronic obstructive pulmonary disease (COPD) are major health problems. COPD may contribute to the disease severity in patients with CVD.

The COPD-CVD association occurs not by chance, but due to shared risk factors and a common pro-inflammatory predisposition. Most studies describe the prevalence of CVD in COPD; this study looked for COPD in patients with CVD.

Objectives:

  1. To study the occurrence of COPD among patients with proven CVD

  2. To study the association of COPD severity and co-morbid CVD.

Study design: This study was conducted at Narayana Health City, among 501 consecutive subjects with proven CVD. COPD was diagnosed by a screening questionnaire and confirmed by spirometry.

Results: There were 501 cases of CVD, 419 [82%] males, 82 [16.4%] females (mean age 66.74 years). COPD was diagnosed in 113 [23%], higher than expected for the general population.There were equal numbers in the GOLD low (Group A +B) and high risk (Groups C+D) groups. Smoking was the commonest risk factor.Of 99 patients had >1 vascular disease, 48.48% had COPD.

COPD did not occur more frequently in those with CAD alone (p= 0.782), but was significantly associated with CeVD [n=8 (12.3%, p = 0.034)], and with PVD [n=17 26.2%, p = 0.047)].

Conclusions:

  1. COPD contributes to morbidity, and perhaps mortality in CVD patients.

  2. Co-existing COPD is commoner in those with >1 vasculopathy.

  3. Patients with vascular diseases should be screened for COPD.

References

  1. McGarvey LP, et al. Ascertainment of causespecific mortality in COPD: operations of the TORCH ClinicalEndpoint Committee. Thorax 2007; 62: 411–15.

  2. GOLD 2012.

  • Comorbidities
  • COPD - diagnosis
  • Smoking
  • Copyright ©ERS 2015
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Prevalence of COPD in vascular diseases
BV Muralimohan, Gayatri Ekbote, Syed Zulkharnain Tousheed, Ranganath Ramanjenaya
European Respiratory Journal Sep 2015, 46 (suppl 59) PA1131; DOI: 10.1183/13993003.congress-2015.PA1131

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Prevalence of COPD in vascular diseases
BV Muralimohan, Gayatri Ekbote, Syed Zulkharnain Tousheed, Ranganath Ramanjenaya
European Respiratory Journal Sep 2015, 46 (suppl 59) PA1131; DOI: 10.1183/13993003.congress-2015.PA1131
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