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Home mechanical ventilation (HMV): Setup and outcome in Europe

Maxime Patout, Michelle Ramsay, Mike Mackie, Elodie Lhuillier, Nathalie Grey, Gill Arbane, Philip Marino, Joerg Steir, Antoine Cuvelier, Jean-François Muir, Patrick Brian Murphy, Nicholas Hart
European Respiratory Journal 2015 46: OA4780; DOI: 10.1183/13993003.congress-2015.OA4780
Maxime Patout
1Intensive Care Unit, Respiratory Department, Rouen University Hospital, Rouen, France
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Michelle Ramsay
2Lane Fox Respiratory Unit, Lane Fox Clinical Respiratory Physiology Research Centre, Guy's & St Thomas' NHS Foundation Trust, Division of Asthma, Allergy and Lung Biology, King's College, London, United Kingdom
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Mike Mackie
2Lane Fox Respiratory Unit, Lane Fox Clinical Respiratory Physiology Research Centre, Guy's & St Thomas' NHS Foundation Trust, Division of Asthma, Allergy and Lung Biology, King's College, London, United Kingdom
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Elodie Lhuillier
1Intensive Care Unit, Respiratory Department, Rouen University Hospital, Rouen, France
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Nathalie Grey
2Lane Fox Respiratory Unit, Lane Fox Clinical Respiratory Physiology Research Centre, Guy's & St Thomas' NHS Foundation Trust, Division of Asthma, Allergy and Lung Biology, King's College, London, United Kingdom
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Gill Arbane
2Lane Fox Respiratory Unit, Lane Fox Clinical Respiratory Physiology Research Centre, Guy's & St Thomas' NHS Foundation Trust, Division of Asthma, Allergy and Lung Biology, King's College, London, United Kingdom
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Philip Marino
2Lane Fox Respiratory Unit, Lane Fox Clinical Respiratory Physiology Research Centre, Guy's & St Thomas' NHS Foundation Trust, Division of Asthma, Allergy and Lung Biology, King's College, London, United Kingdom
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Joerg Steir
2Lane Fox Respiratory Unit, Lane Fox Clinical Respiratory Physiology Research Centre, Guy's & St Thomas' NHS Foundation Trust, Division of Asthma, Allergy and Lung Biology, King's College, London, United Kingdom
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Antoine Cuvelier
1Intensive Care Unit, Respiratory Department, Rouen University Hospital, Rouen, France
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Jean-François Muir
1Intensive Care Unit, Respiratory Department, Rouen University Hospital, Rouen, France
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Patrick Brian Murphy
2Lane Fox Respiratory Unit, Lane Fox Clinical Respiratory Physiology Research Centre, Guy's & St Thomas' NHS Foundation Trust, Division of Asthma, Allergy and Lung Biology, King's College, London, United Kingdom
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Nicholas Hart
2Lane Fox Respiratory Unit, Lane Fox Clinical Respiratory Physiology Research Centre, Guy's & St Thomas' NHS Foundation Trust, Division of Asthma, Allergy and Lung Biology, King's College, London, United Kingdom
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Abstract

Introduction: HMV is widely used to treat chronic respiratory failure. The aim of this study was to describe the initial HMV setup and subsequent outcome based on diagnostic group.

Methods: Retrospective study from bespoke prospective database entry, including all patients setup on HMV at the Lane Fox Respiratory Unit in London from 1st January 2008 to 31st December 2014.

Results: 1135 patients were set up on HMV. 22% (n:249) neuromuscular disease (NMD), 9% (n:99) chest wall disease (CWD); 23% (n:258) obstructive airway disease (OAD); 12% (n:139) hypercapnic obstructive sleep apnea (OSA); 28% (n:317) OSA-Obesity hypoventilation syndrome (OHS), 5% (n:60) COPD-OSA, 1% (n:13) other conditions. HMV setups increased from 116 in 2008 to 212 in 2014. Baseline data are reported in fig. 1.

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Cumulative survival differed with underlying disease.

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5 year survival was 57% for NMD, 59% for CWD, 31% for OAD, 79% for OSA-OHS, 73% for OSA, 63% for COPD-OSA, 26% for other conditions

Conclusion: Demand for HMV is increasing with OAD, having the poorest outcome and OSA-OHS having the best outcome at 5 years. Of clinical importance, COPD-OSA overlap patients have an improved outcome compared with COPD patients.

  • Non-invasive ventilation - long-term
  • Epidemiology
  • Chronic disease
  • Copyright ©ERS 2015
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Home mechanical ventilation (HMV): Setup and outcome in Europe
Maxime Patout, Michelle Ramsay, Mike Mackie, Elodie Lhuillier, Nathalie Grey, Gill Arbane, Philip Marino, Joerg Steir, Antoine Cuvelier, Jean-François Muir, Patrick Brian Murphy, Nicholas Hart
European Respiratory Journal Sep 2015, 46 (suppl 59) OA4780; DOI: 10.1183/13993003.congress-2015.OA4780

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Home mechanical ventilation (HMV): Setup and outcome in Europe
Maxime Patout, Michelle Ramsay, Mike Mackie, Elodie Lhuillier, Nathalie Grey, Gill Arbane, Philip Marino, Joerg Steir, Antoine Cuvelier, Jean-François Muir, Patrick Brian Murphy, Nicholas Hart
European Respiratory Journal Sep 2015, 46 (suppl 59) OA4780; DOI: 10.1183/13993003.congress-2015.OA4780
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