Table of Contents

Original Articles

• COPD

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    Benefits of physical activity on COPD hospitalisation depend on intensity

    David Donaire-Gonzalez, Elena Gimeno-Santos, Eva Balcells, Jordi de Batlle, Maria A. Ramon, Esther Rodriguez, Eva Farrero, Marta Benet, Stefano Guerra, Jaume Sauleda, Antoni Ferrer, Jaume Ferrer, Joan A. Barberà, Robert Rodriguez-Roisin, Joaquim Gea, Alvar Agustí, Josep M. Antó, Judith Garcia-Aymerich, the PAC-COPD Study Group

    European Respiratory Journal 46 (5) 1281-1289; DOI: 10.1183/13993003.01699-2014 Published 31 October 2015

    • Disclosures
    • Supplementary material

• Asthma and occupational lung disease

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    Incidence of rhinitis and asthma related to welding in Northern Europe

    Torgeir Storaas, Jan-Paul Zock, Ana Espinosa Morano, Mathias Holm, Eythor Bjørnsson, Bertil Forsberg, Thorarinn Gislason, Christer Janson, Dan Norback, Ernst Omenaas, Vivi Schlünssen, Kjell Torén, Cecilie Svanes

    European Respiratory Journal 46 (5) 1290-1297; DOI: 10.1183/13993003.02345-2014 Published 31 October 2015

• Asthma

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    A repeated short educational intervention improves asthma control and quality of life

    Vicente Plaza, Meritxell Peiró, Montserrat Torrejón, Monica Fletcher, Antolín López-Viña, José María Ignacio, José Antonio Quintano, Santiago Bardagí, Ignasi Gich on behalf of the PROMETHEUS Study Group

    European Respiratory Journal 46 (5) 1298-1307; DOI: 10.1183/13993003.00458-2015 Published 31 October 2015
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    Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort

    Dominick E. Shaw, Ana R. Sousa, Stephen J. Fowler, Louise J. Fleming, Graham Roberts, Julie Corfield, Ioannis Pandis, Aruna T. Bansal, Elisabeth H. Bel, Charles Auffray, Chris H. Compton, Hans Bisgaard, Enrica Bucchioni, Massimo Caruso, Pascal Chanez, Barbro Dahlén, Sven-Erik Dahlen, Kerry Dyson, Urs Frey, Thomas Geiser, Maria Gerhardsson de Verdier, David Gibeon, Yi-ke Guo, Simone Hashimoto, Gunilla Hedlin, Elizabeth Jeyasingham, Pieter-Paul W. Hekking, Tim Higenbottam, Ildikó Horváth, Alan J. Knox, Norbert Krug, Veit J. Erpenbeck, Lars X. Larsson, Nikos Lazarinis, John G. Matthews, Roelinde Middelveld, Paolo Montuschi, Jacek Musial, David Myles, Laurie Pahus, Thomas Sandström, Wolfgang Seibold, Florian Singer, Karin Strandberg, Jorgen Vestbo, Nadja Vissing, Christophe von Garnier, Ian M. Adcock, Scott Wagers, Anthony Rowe, Peter Howarth, Ariane H. Wagener, Ratko Djukanovic, Peter J. Sterk, Kian Fan Chung on behalf of the U-BIOPRED Study Group

    European Respiratory Journal 46 (5) 1308-1321; DOI: 10.1183/13993003.00779-2015 Published 31 October 2015

    • Supplementary material
    • Disclosures
    • ERJ Podcast

• Asthma and paediatric pulmonology

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    The burden of severe asthma in childhood and adolescence: results from the paediatric U-BIOPRED cohorts

    Louise Fleming, Clare Murray, Aruna T. Bansal, Simone Hashimoto, Hans Bisgaard, Andrew Bush, Urs Frey, Gunilla Hedlin, Florian Singer, Wim M. van Aalderen, Nadja H. Vissing, Zaraquiza Zolkipli, Anna Selby, Stephen Fowler, Dominick Shaw, Kian Fan Chung, Ana R. Sousa, Scott Wagers, Julie Corfield, Ioannis Pandis, Anthony Rowe, Elena Formaggio, Peter J. Sterk, Graham Roberts on behalf of the U-BIOPRED Study Group

    European Respiratory Journal 46 (5) 1322-1333; DOI: 10.1183/13993003.00780-2015 Published 31 October 2015

    • Disclosures
    • Supplementary material
    • ERJ Podcast

• Paediatric pulmonology

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    Infant respiratory infections and later respiratory hospitalisation in childhood

    Hannah C. Moore, Graham L. Hall, Nicholas de Klerk

    European Respiratory Journal 46 (5) 1334-1341; DOI: 10.1183/13993003.00587-2015 Published 31 October 2015

    • Supplementary material
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    Maternal body mass index, neonatal lung function and respiratory symptoms in childhood

    Jacobien B. Eising, Cuno S.P.M. Uiterwaal, Cornelis K. van der Ent

    European Respiratory Journal 46 (5) 1342-1349; DOI: 10.1183/13993003.00784-2014 Published 31 October 2015

    • Disclosures
    • Supplementary material

• Cystic fibrosis

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    miR-17 overexpression in cystic fibrosis airway epithelial cells decreases interleukin-8 production

    Irene K. Oglesby, Sebastian F. Vencken, Raman Agrawal, Kevin Gaughan, Kevin Molloy, Gerard Higgins, Paul McNally, Noel G. McElvaney, Marcus A. Mall, Catherine M. Greene

    European Respiratory Journal 46 (5) 1350-1360; DOI: 10.1183/09031936.00163414 Published 31 October 2015

    • Disclosures
    • Supplementary material

• Sleep

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    Association of short-term ozone and temperature with sleep disordered breathing

    Gerhard Weinreich, Thomas E. Wessendorf, Noreen Pundt, Gudrun Weinmayr, Frauke Hennig, Susanne Moebus, Stefan Möhlenkamp, Raimund Erbel, Karl-Heinz Jöckel, Helmut Teschler, Barbara Hoffmann on behalf of the Heinz Nixdorf Recall study group

    European Respiratory Journal 46 (5) 1361-1369; DOI: 10.1183/13993003.02255-2014 Published 31 October 2015

• Pulmonary vascular disease and interstitial lung disease

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    Pulmonary hypertension in idiopathic pulmonary fibrosis with mild-to-moderate restriction

    Ganesh Raghu, Steven D. Nathan, Juergen Behr, Kevin K. Brown, James J. Egan, Steven M. Kawut, Kevin R. Flaherty, Fernando J. Martinez, Athol U. Wells, Lixin Shao, Huafeng Zhou, Noreen Henig, Javier Szwarcberg, Hunter Gillies, Alan B. Montgomery, Thomas G. O'Riordan

    European Respiratory Journal 46 (5) 1370-1377; DOI: 10.1183/13993003.01537-2014 Published 31 October 2015

    • Disclosures
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    Severe pulmonary hypertension in lung disease: phenotypes and response to treatment

    Melanie J. Brewis, Alistair C. Church, Martin K. Johnson, Andrew J. Peacock

    European Respiratory Journal 46 (5) 1378-1389; DOI: 10.1183/13993003.02307-2014 Published 31 October 2015

    • Supplementary material
    • Disclosures

• Pulmonary vascular disease

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    New potential diagnostic biomarkers for pulmonary hypertension

    Svenja L. Tiede, Henning Gall, Oliver Dörr, Marina dos Santos Guilherme, Christian Troidl, Christoph Liebetrau, Sandra Voss, Robert Voswinckel, Ralph T. Schermuly, Werner Seeger, Friedrich Grimminger, Andreas M. Zeiher, Stefanie Dimmeler, Helge Möllmann, Christian W. Hamm, Hossein Ardeschir Ghofrani, Holger M. Nef

    European Respiratory Journal 46 (5) 1390-1396; DOI: 10.1183/13993003.00187-2015 Published 31 October 2015

    • Supplementary material
    • Disclosures

• Tuberculosis

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    Benefit of treatment of latent tuberculosis infection in individual patients

    Claudia C. Dobler, Andrew Martin, Guy B. Marks

    European Respiratory Journal 46 (5) 1397-1406; DOI: 10.1183/13993003.00577-2015 Published 31 October 2015

    • Supplementary material

• Respiratory infections

  • Open Access

    Cost-effectiveness of adult pneumococcal conjugate vaccination in the Netherlands

    Marie-Josée J. Mangen, Mark H. Rozenbaum, Susanne M. Huijts, Cornelis H. van Werkhoven, Douwe F. Postma, Mark Atwood, Anna M.M. van Deursen, Arie van der Ende, Diederick E. Grobbee, Elisabeth A.M. Sanders, Reiko Sato, Theo J.M. Verheij, Conrad E. Vissink, Marc J.M. Bonten, G. Ardine de Wit

    European Respiratory Journal 46 (5) 1407-1416; DOI: 10.1183/13993003.00325-2015 Published 31 October 2015

    • Disclosures
    • Supplementary material

• Interstitial and orphan lung disease

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    Increased alveolar soluble annexin V promotes lung inflammation and fibrosis

    Susan Buckley, Wei Shi, Wei Xu, Mark R. Frey, Rex Moats, Annie Pardo, Moises Selman, David Warburton

    European Respiratory Journal 46 (5) 1417-1429; DOI: 10.1183/09031936.00002115 Published 31 October 2015

    • Disclosures
    • Supplementary material

• Lung transplantation

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    Linking clinical phenotypes of chronic lung allograft dysfunction to changes in lung structure

    Stijn E. Verleden, Dragoş M. Vasilescu, John E. McDonough, David Ruttens, Robin Vos, Elly Vandermeulen, Hannelore Bellon, Rachel Geenens, Erik K. Verbeken, Johny Verschakelen, Dirk E. Van Raemdonck, Wim A. Wuyts, Youri Sokolow, Christiane Knoop, Joel D. Cooper, James C. Hogg, Geert M. Verleden, Bart M. Vanaudenaerde

    European Respiratory Journal 46 (5) 1430-1439; DOI: 10.1183/09031936.00010615 Published 31 October 2015

    • Supplementary material
    • Disclosures

• Lung cancer

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    Erlotinib versus carboplatin and paclitaxel in advanced lepidic adenocarcinoma: IFCT-0504

    Jacques Cadranel, Radj Gervais, Patrick Merle, Denis Moro-Sibilot, Virginie Westeel, Laurence Bigay-Game, Elisabeth Quoix, Sylvie Friard, Fabrice Barlesi, Claire Lethrosne, Lionel Moreau, Isabelle Monnet, Mathieu Salaun, Gérard Oliviero, Pierre-Jean Souquet, Martine Antoine, Alexandra Langlais, Franck Morin, Marie Wislez, Gérard Zalcman on behalf of the Intergroupe Francophone de Cancérologie Thoracique (IFCT)

    European Respiratory Journal 46 (5) 1440-1450; DOI: 10.1183/13993003.02358-2014 Published 31 October 2015

    • Disclosures
    • Supplementary material

• Lung biology and experimental studies

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    Disruption of pulmonary lipid homeostasis drives cigarette smoke-induced lung inflammation in mice

    Mathieu C. Morissette, Pamela Shen, Danya Thayaparan, Martin R. Stämpfli

    European Respiratory Journal 46 (5) 1451-1460; DOI: 10.1183/09031936.00216914 Published 31 October 2015

    • Disclosures