European Respiratory Journal: 46 (4)

01 October 2015; volume 46, issue 4

Electronic Resources

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ERJ October Podcast: new guidelines for diagnosis and treatment of pulmonary hypertension
European Respiratory Journal 46 (4) E58; DOI: 10.1183/13993003.20154604.E58 Published 30 September 2015
ERJ Podcast

Editorials

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The 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: a practical chronicle of progress
Edmund M.T. Lau, Yuichi Tamura, Michael D. McGoon, Olivier Sitbon

European Respiratory Journal 46 (4) 879-882; DOI: 10.1183/13993003.01177-2015 Published 30 September 2015
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The 2015 guidelines for idiopathic pulmonary fibrosis: an important chapter in the evolution of the management of patients with IPF
Kevin C. Wilson, Ganesh Raghu

European Respiratory Journal 46 (4) 883-886; DOI: 10.1183/13993003.01335-2015 Published 30 September 2015
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Classification of antituberculosis drugs: a new proposal based on the most recent evidence
Jose A. Caminero, Anna Scardigli

European Respiratory Journal 46 (4) 887-893; DOI: 10.1183/13993003.00432-2015 Published 30 September 2015
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Multitasking basal cells: combining stem cell and innate immune duties
Renat Shaykhiev

European Respiratory Journal 46 (4) 894-897; DOI: 10.1183/13993003.00521-2015 Published 30 September 2015
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The double-edged sword of neutrophilic inflammation in bronchiectasis
Miguel Ángel Martínez-García, Concepción Prados Sánchez, Rosa María Girón Moreno

European Respiratory Journal 46 (4) 898-900; DOI: 10.1183/13993003.00961-2015 Published 30 September 2015
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Should COPD stand for “comorbidity-related obstructive pulmonary disease”?
Don D. Sin

European Respiratory Journal 46 (4) 901-902; DOI: 10.1183/13993003.01112-2015 Published 30 September 2015
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ESC/ERS Guidelines

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2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
Nazzareno Galiè, Marc Humbert, Jean-Luc Vachiery, Simon Gibbs, Irene Lang, Adam Torbicki, Gérald Simonneau, Andrew Peacock, Anton Vonk Noordegraaf, Maurice Beghetti, Ardeschir Ghofrani, Miguel Angel Gomez Sanchez, Georg Hansmann, Walter Klepetko, Patrizio Lancellotti, Marco Matucci, Theresa McDonagh, Luc A. Pierard, Pedro T. Trindade, Maurizio Zompatori, Marius Hoeper

European Respiratory Journal 46 (4) 903-975; DOI: 10.1183/13993003.01032-2015 Published 30 September 2015
Supplementary material
Disclosures
ERJ Podcast
Erratum

ERS/ATS Task Force

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An official European Respiratory Society/American Thoracic Society research statement: interstitial pneumonia with autoimmune features
Aryeh Fischer, Katerina M. Antoniou, Kevin K. Brown, Jacques Cadranel, Tamera J. Corte, Roland M. du Bois, Joyce S. Lee, Kevin O. Leslie, David A. Lynch, Eric L. Matteson, Marta Mosca, Imre Noth, Luca Richeldi, Mary E. Strek, Jeffrey J. Swigris, Athol U. Wells, Sterling G. West, Harold R. Collard, Vincent Cottin

European Respiratory Journal 46 (4) 976-987; DOI: 10.1183/13993003.00150-2015 Published 30 September 2015
Disclosures
Supplementary material

Original Articles

COPD

Open Access
The PROactive instruments to measure physical activity in patients with chronic obstructive pulmonary disease
Elena Gimeno-Santos, Yogini Raste, Heleen Demeyer, Zafeiris Louvaris, Corina de Jong, Roberto A. Rabinovich, Nicholas S. Hopkinson, Michael I. Polkey, Ioannis Vogiatzis, Maggie Tabberer, Fabienne Dobbels, Nathalie Ivanoff, Willem I. de Boer, Thys van der Molen, Karoly Kulich, Ignasi Serra, Xavier Basagaña, Thierry Troosters, Milo A. Puhan, Niklas Karlsson, Judith Garcia-Aymerich

European Respiratory Journal 46 (4) 988-1000; DOI: 10.1183/09031936.00183014 Published 30 September 2015
Supplementary material
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Molecular and clinical diseasome of comorbidities in exacerbated COPD patients
Rosa Faner, Alba Gutiérrez-Sacristán, Ady Castro-Acosta, Solène Grosdidier, Wenqi Gan, Milagros Sánchez-Mayor, Jose Luis Lopez-Campos, Francisco Pozo-Rodriguez, Ferran Sanz, David Mannino, Laura I. Furlong, Alvar Agusti

European Respiratory Journal 46 (4) 1001-1010; DOI: 10.1183/13993003.00763-2015 Published 30 September 2015
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Asthma

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Gender differences in adult-onset asthma: results from the Swiss SAPALDIA cohort study
Sofie Hansen, Nicole Probst-Hensch, Dirk Keidel, Julia Dratva, Robert Bettschart, Marco Pons, Luc Burdet, Pierre-Olivier Bridevaux, Tamara Schikowski, Christian Schindler, Thierry Rochat, Elisabeth Zemp

European Respiratory Journal 46 (4) 1011-1020; DOI: 10.1183/13993003.02278-2014 Published 30 September 2015
Supplementary material
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Bronchiectasis

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A randomised, placebo-controlled study of the CXCR2 antagonist AZD5069 in bronchiectasis
Anthony De Soyza, Ian Pavord, J. Stuart Elborn, David Smith, Heather Wray, Margareta Puu, Bengt Larsson, Robert Stockley

European Respiratory Journal 46 (4) 1021-1032; DOI: 10.1183/13993003.00148-2015 Published 30 September 2015
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Cystic fibrosis

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Short-chain fatty acids affect cystic fibrosis airway inflammation and bacterial growth
Peyman Ghorbani, Prisila Santhakumar, Qingda Hu, Pascal Djiadeu, Thomas M.S. Wolever, Nades Palaniyar, Hartmut Grasemann

European Respiratory Journal 46 (4) 1033-1045; DOI: 10.1183/09031936.00143614 Published 30 September 2015
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Supplementary material
Open Access
Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis
Helen L. Barr, Nigel Halliday, Miguel Cámara, David A. Barrett, Paul Williams, Douglas L. Forrester, Rebecca Simms, Alan R. Smyth, David Honeybourne, Joanna L. Whitehouse, Edward F. Nash, Jane Dewar, Andrew Clayton, Alan J. Knox, Andrew W. Fogarty

European Respiratory Journal 46 (4) 1046-1054; DOI: 10.1183/09031936.00225214 Published 30 September 2015
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Supplementary material
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Lung clearance index in cystic fibrosis subjects treated for pulmonary exacerbations
Nicole Sonneveld, Sanja Stanojevic, Reshma Amin, Paul Aurora, Jane Davies, J. Stuart Elborn, Alex Horsley, Philipp Latzin, Katherine O'Neill, Paul Robinson, Emma Scrase, Hiran Selvadurai, Padmaja Subbarao, Liam Welsh, Sophie Yammine, Felix Ratjen

European Respiratory Journal 46 (4) 1055-1064; DOI: 10.1183/09031936.00211914 Published 30 September 2015
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Sleep

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Biomarkers of oxidative stress following continuous positive airway pressure withdrawal: data from two randomised trials
John R. Stradling, Esther I. Schwarz, Christian Schlatzer, Ari R. Manuel, Regent Lee, Charalambos Antoniades, Malcolm Kohler

European Respiratory Journal 46 (4) 1065-1071; DOI: 10.1183/09031936.00023215 Published 30 September 2015
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Human intermittent hypoxia-induced respiratory plasticity is not caused by inflammation
Andrew E. Beaudin, Xavier Waltz, Matiram Pun, Katherine E. Wynne-Edwards, Sofia B. Ahmed, Todd J. Anderson, Patrick J. Hanly, Marc J. Poulin

European Respiratory Journal 46 (4) 1072-1083; DOI: 10.1183/09031936.00007415 Published 30 September 2015
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Supplementary material

Pulmonary vascular disease

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Chymase: a multifunctional player in pulmonary hypertension associated with lung fibrosis
Djuro Kosanovic, Himal Luitel, Bhola Kumar Dahal, Teodora Cornitescu, Wiebke Janssen, A.H. Jan Danser, Ingrid M. Garrelds, Jo G.R. De Mey, Gregorio Fazzi, Paul Schiffers, Marc Iglarz, Walter Fischli, Hossein Ardeschir Ghofrani, Norbert Weissmann, Friedrich Grimminger, Werner Seeger, Irwin Reiss, Ralph Theo Schermuly

European Respiratory Journal 46 (4) 1084-1094; DOI: 10.1183/09031936.00018215 Published 30 September 2015
Supplementary material

Tuberculosis

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Biomarkers for risk of developing active tuberculosis in contacts of TB patients: a prospective cohort study
Niaina Rakotosamimanana, Vincent Richard, Vaomalala Raharimanga, Brigitte Gicquel, T. Mark Doherty, Alimuddin Zumla, Voahangy Rasolofo Razanamparany

European Respiratory Journal 46 (4) 1095-1103; DOI: 10.1183/13993003.00263-2015 Published 30 September 2015
Supplementary material
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Tuberculosis associates with both airflow obstruction and low lung function: BOLD results
André F.S. Amaral, Sonia Coton, Bernet Kato, Wan C. Tan, Michael Studnicka, Christer Janson, Thorarinn Gislason, David Mannino, Eric D. Bateman, Sonia Buist, Peter G.J. Burney

European Respiratory Journal 46 (4) 1104-1112; DOI: 10.1183/13993003.02325-2014 Published 30 September 2015
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Interstitial and orphan lung disease

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Comorbidities in idiopathic pulmonary fibrosis patients: a systematic literature review
Ganesh Raghu, Valeria C. Amatto, Jürgen Behr, Susanne Stowasser

European Respiratory Journal 46 (4) 1113-1130; DOI: 10.1183/13993003.02316-2014 Published 30 September 2015
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Lung cancer

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Time trends in surgery for lung cancer in France from 2005 to 2012: a nationwide study
Marie-Catherine Morgant, Pierre-Benoit Pagès, Bastien Orsini, Pierre-Emmanuel Falcoz, Pascal-Alexandre Thomas, Françoise Le Pimpec Barthes, Marcel Dahan, Alain Bernard

European Respiratory Journal 46 (4) 1131-1139; DOI: 10.1183/13993003.00354-2015 Published 30 September 2015

Endobronchial ultrasound

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Simulator training for endobronchial ultrasound: a randomised controlled trial
Lars Konge, Paul Frost Clementsen, Charlotte Ringsted, Valentina Minddal, Klaus Richter Larsen, Jouke T. Annema

European Respiratory Journal 46 (4) 1140-1149; DOI: 10.1183/13993003.02352-2015 Published 30 September 2015
Supplementary material

Mechanisms of lung disease

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Preclinical validation and imaging of Wnt-induced repair in human 3D lung tissue cultures
Franziska E. Uhl, Sarah Vierkotten, Darcy E. Wagner, Gerald Burgstaller, Rita Costa, Ina Koch, Michael Lindner, Silke Meiners, Oliver Eickelberg, Melanie Königshoff

European Respiratory Journal 46 (4) 1150-1166; DOI: 10.1183/09031936.00183214 Published 30 September 2015
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Review

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Potassium channels in pulmonary arterial hypertension
Olivier Boucherat, Sophie Chabot, Fabrice Antigny, Frédéric Perros, Steeve Provencher, Sébastien Bonnet

European Respiratory Journal 46 (4) 1167-1177; DOI: 10.1183/13993003.00798-2015 Published 30 September 2015

Series

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Pulmonary vascular resistance and compliance relationship in pulmonary hypertension
Denis Chemla, Edmund M.T. Lau, Yves Papelier, Pierre Attal, Philippe Hervé

European Respiratory Journal 46 (4) 1178-1189; DOI: 10.1183/13993003.00741-2015 Published 30 September 2015

Agora

Research letters

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End-of-life care in oxygen-dependent COPD and cancer: a national population-based study
Zainab Ahmadi, Staffan Lundström, Christer Janson, Peter Strang, Margareta Emtner, David C. Currow, Magnus Ekström

European Respiratory Journal 46 (4) 1190-1193; DOI: 10.1183/09031936.00035915 Published 30 September 2015
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Effects of ageing and smoking on pulmonary computed tomography scans using parametric response mapping
Ilse M. Boudewijn, Dirkje S. Postma, Eef D. Telenga, Nick H.T. ten Hacken, Wim Timens, Matthijs Oudkerk, Brian D. Ross, Craig J. Galbán, Maarten van den Berge

European Respiratory Journal 46 (4) 1193-1196; DOI: 10.1183/09031936.00009415 Published 30 September 2015
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Accuracy of chest high-resolution computed tomography in diagnosing diffuse cystic lung diseases
Nishant Gupta, Riffat Meraj, Daniel Tanase, Laura E. James, Kuniaki Seyama, David A. Lynch, Masanori Akira, Cristopher A. Meyer, Stephen J. Ruoss, Charles D. Burger, Lisa R. Young, Khalid F. Almoosa, Srihari Veeraraghavan, Alan F. Barker, Augustine S. Lee, Daniel F. Dilling, Yoshikazu Inoue, Corey J. Cudzilo, Muhammad A. Zafar, Francis X. McCormack

European Respiratory Journal 46 (4) 1196-1199; DOI: 10.1183/13993003.00570-2015 Published 30 September 2015
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Blood stem cell transplantation to treat cystic lung light chain deposition disease
Aurélie Le Borgne, Grégoire Prévot, Isabelle Rouquette, Anne Huynh, Laurent Têtu, Fabrice Projetti, Miguel Carreiro, Raphaël Borie, Arnaud Jaccard, Christian Recher, Alain Didier

European Respiratory Journal 46 (4) 1199-1202; DOI: 10.1183/13993003.00577-2014 Published 30 September 2015
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Reversal of central sleep apnoea with change from methadone to buprenorphine-naloxone: a case report
David Wang, Nicholas Lintzeris, Stefanie Leung, Paul S. Haber, Brendon J. Yee, Ronald R. Grunstein

European Respiratory Journal 46 (4) 1202-1205; DOI: 10.1183/09031936.00051315 Published 30 September 2015
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Linezolid tolerability in multidrug-resistant tuberculosis: a retrospective study
Mathieu S. Bolhuis, Simon Tiberi, Giovanni Sotgiu, Saverio De Lorenzo, Jos G.W. Kosterink, Tjip S. van der Werf, Giovanni Battista Migliori, Jan-Willem C. Alffenaar

European Respiratory Journal 46 (4) 1205-1207; DOI: 10.1183/13993003.00606-2015 Published 30 September 2015
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Airway bacteria and respiratory symptoms are common in ambulatory HIV-positive UK adults
Camus Nimmo, Santino Capocci, Isobella Honeyborne, James Brown, Janey Sewell, Sarah Thurston, Margaret Johnson, Timothy D. McHugh, Marc Lipman

European Respiratory Journal 46 (4) 1208-1211; DOI: 10.1183/13993003.00361-2015 Published 30 September 2015
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Nasal decongestant exposure in patients with pulmonary arterial hypertension: a pilot study
Swanny Perrin, David Montani, Caroline O'Connell, Sven Günther, Barbara Girerd, Laurent Savale, Christophe Guignabert, Olivier Sitbon, Gerald Simonneau, Marc Humbert, Marie-Camille Chaumais

European Respiratory Journal 46 (4) 1211-1214; DOI: 10.1183/13993003.00051-2015 Published 30 September 2015
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Pulmonary tumour thrombotic microangiopathy: unclassifiable pulmonary hypertension?
Neelam Kumar, Laura C. Price, M. Angeles Montero, Konstantinos Dimopoulos, Athol U. Wells, S. John Wort

European Respiratory Journal 46 (4) 1214-1217; DOI: 10.1183/13993003.00052-2015 Published 30 September 2015
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Switching to nintedanib after discontinuation of pirfenidone due to adverse events in IPF
Katrin Milger, Nikolaus Kneidinger, Claus Neurohr, Frank Reichenberger, Jürgen Behr

European Respiratory Journal 46 (4) 1217-1221; DOI: 10.1183/13993003.00584-2015 Published 30 September 2015
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Correspondence

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Pulse oximetry oxygen saturation during the 6-min walk test: a limit for stopping the test without resuming it
Giancarlo Piaggi, Simone Gambazza, Riccardo Guarise, Manuela Piran

European Respiratory Journal 46 (4) 1222-1223; DOI: 10.1183/13993003.00670-2015 Published 30 September 2015
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Guidance for the regulatory status of allergen extracts in clinical trials
Zuzana Diamant, Maurits van Maaren, Roy Gerth van Wijk, Jacobus R.B.J. Brouwers, Herman Pieterse

European Respiratory Journal 46 (4) 1223-1225; DOI: 10.1183/13993003.00729-2015 Published 30 September 2015
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Erratum

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“Dead space: the physiology of wasted ventilation.” H. Thomas Robertson. Eur Respir J 2015; 45: 1704–1716.
European Respiratory Journal 46 (4) 1226; DOI: 10.1183/09031936.50137614 Published 30 September 2015

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Table of Contents

Electronic Resources

Editorials

ESC/ERS Guidelines

ERS/ATS Task Force

Original Articles

COPD

Asthma

Bronchiectasis

Cystic fibrosis

Sleep

Pulmonary vascular disease

Tuberculosis

Interstitial and orphan lung disease

Lung cancer

Endobronchial ultrasound

Mechanisms of lung disease

Review

Series

Agora

Research letters

Correspondence

Erratum

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